Results 11 to 20 of about 2,423,946 (178)

The significance of anti-PLA2R antibody in the diagnosis and treatment of primary membranous nephropathy

Linchuang shenzangbing zazhi, 2019
Primary membranous nephropathy(PMN) is a glomerulus-specific autoimmune disorder mainly caused by challenge of autoantibodies against the recently discovered antigens located on podocytes, such as the M-type phospholipase A2 receptor(PLA2R), the ...
XU Dong-mei, LIU Yi-peng
doaj   +2 more sources

Anti-PLA2R Antibody Levels and Clinical Risk Factors for Treatment Nonresponse in Membranous Nephropathy. [PDF]

Clin J Am Soc Nephrol, 2023
Background The 2021 Kidney Disease Improving Global Outcomes (KDIGO) guidelines recommend following anti-phospholipase A2 receptor (PLA2R) antibody levels as a marker of treatment response in membranous nephropathy; however, the optimal timing to evaluate antibody levels and how to combine them with other ...
Barbour SJ, Fervenza FC, Induruwage D, Brenchley PE, Rovin B, Hladunewich MA, Reich HN, Lafayette R, Aslam N, Appel GB, Zand L, Kiryluk K, Liu L, Cattran DC, MENTOR Trial Investigators.   +14 more
europepmc   +5 more sources

Retrospective study: clinicopathological features and prognosis of idiopathic membranous nephropathy with seronegative anti-phospholipase A2 receptor antibody [PDF]

PeerJ, 2020
Background To discuss the clinicopathological features and prognosis of patients with idiopathic membranous nephropathy (IMN) who are serum-negative for the anti-PLA2R antibody.
Wenkai Guo, Yan Zhang, Caifeng Gao, Jing Huang, Jiatong Li, Rong Wang, Bing Chen   +6 more
doaj   +3 more sources

The relationship of anti-phospholipase A2 receptor antibody and C5a complement with disease activity and short-term outcome in idiopathic membranous nephropathy

Journal of the Formosan Medical Association, 2019
Background: The binding of anti-phospholipase A2 receptor (anti-PLA2R) antibody to podocyte and complement activation is the mechanisms of idiopathic membranous nephropathy (IMN).
Jyun Ni Chi, Tai Shuan Lai, Ching Fang Wu, Tian Yi Fu, Yu Hsiang Chou, Yen Ling Chiu, Wei Chou Lin, Wen Chih Chiang, Yung Ming Chen, Ming Shiou Wu   +9 more
doaj   +2 more sources

Anti-Phospholipase A2 Receptor (PLA2R) Antibody and Glomerular PLA2R Expression in Japanese Patients with Membranous Nephropathy.

PLoS ONE, 2016
The phospholipase A2 receptor (PLA2R) is the major target antigen (Ag) in idiopathic membranous nephropathy (IMN). Recently, several types of immunoassay systems for anti-PLA2R antibody (Ab) have been developed.
Kei Hihara, Masayuki Iyoda, Shohei Tachibana, Ken Iseri, Tomohiro Saito, Yasutaka Yamamoto, Taihei Suzuki, Yukihiro Wada, Kei Matsumoto, Takanori Shibata   +9 more
doaj   +2 more sources

Anti-phospholipase A2 receptor antibody as a prognostic marker in patients with primary membranous nephropathy

Kidney Research and Clinical Practice, 2018
Background: Phospholipase A2 receptor (PLA2R) has been identified as a major autoantigen in primary membranous nephropathy (MN). We evaluated the association between anti-PLA2R antibodies and clinical outcome in Korean patients with primary MN.
Eun Joo Song, Kye Hwa Jeong, Young Ae Yang, Jeong-Hoon Lim, Hee-Yeon Jung, Ji-Young Choi, Jang-Hee Cho, Chan-Duck Kim, Yong-Lim Kim, Sun-Hee Park   +9 more
doaj   +2 more sources

Anti-phospholipase A2 receptor antibody in idiopathic membranous nephropathy: A report from Iranian population [PDF]

Journal of Nephropathology, 2013
Background: Idiopathic Membranous Nephropathy (iMN) is the most common cause of nephrotic syndrome in adults. Approximately one third of patients with iMN progress to end-stage renal disease.
MohammadReza Ardalan, Ali Ghafari, Fatemeh Hamzavi, Hamid Nasri, Behrooz Baradaran, Jafar Majidi, Behrooz Nikbin   +6 more
doaj   +3 more sources

Serum anti-PLA2R antibody and glomerular PLA2R deposition in Chinese patients with membranous nephropathy: A cross-sectional study. [PDF]

Medicine (Baltimore), 2017
M-type phospholipase A2 receptor (PLA2R) is the major target antigen in primary membranous nephropathy (PMN). Previous studies have evaluated the diagnostic value of serum anti-PLA2R antibody. However, the correlation of serum anti-PLA2R antibody and glomerular PLA2R deposition, and their association with clinical characteristics need to be further ...
Pang L, Zhang AM, Li HX, Du JL, Jiao LL, Duan N, Liu Y, Yu D.   +7 more
europepmc   +4 more sources

Serum phospholipase A2 receptor antibody is associated with thrombogenesis in patients with idiopathic membranous nephropathy [PDF]

Kidney & Blood Pressure Research
Introduction: Patients with idiopathic membranous nephropathy (IMN) are particularly susceptible to thromboembolism (TE). The phospholipase A2 receptor (PLA2R) antibody (Ab) has been indicated to work as an independent risk predictor for venous TE in IMN.
Qinling Zhang, Guiling Liu
doaj   +2 more sources

Primary antiphospholipid syndrome associated with anti-phospholipase A2 receptor antibody-positive membranous nephropathy

BMC Nephrology, 2020
Background The kidney is a major target in primary antiphospholipid syndrome. Several types of nephropathy have been reported, the most frequent being acute or chronic specific vascular nephropathies and membranous nephropathy.
Maxime Teisseyre, Hélène Perrochia, Pascal Reboul, Sylvain Cariou, Sophie Renaud, Cédric Aglae, Olivier Moranne   +6 more
doaj   +2 more sources