Results 31 to 40 of about 2,423,946 (178)

Distinct Complement Activation Profiles Between NELL1‐ and PLA2R‐Associated Membranous Nephropathy: A Clinicopathological and Proteomic Study [PDF]

Nephrology (Carlton)
We compared the clinicopathological features and complement activation profiles of PLA2R‐associated and NELL1‐associated membranous nephropathy. NELL1‐associated membranous nephropathy was associated with older age, more chronic histologic changes and less glomerular C3 and C4d deposition.
Suzuki T, Dedong K, Kawanishi K, Ueda M, Kajio Y, Kobayashi K, Kanazawa N, Takahashi‐Kobayashi M, Usui J, Baba M, Honda H, Honda K, Iyoda M.   +12 more
europepmc   +2 more sources

Anti-PLA2R Antibodies in Chinese Patients with Membranous Nephropathy [PDF]

Medical Science Monitor, 2016
BACKROUND ~This study used two standardized methods to evaluate anti-PLA2R antibody in serum of primary membranous nephropathy (PMN) among Chinese patients to determine  Anti-PLA2R antibody distribution and whether immunological reactivity reflected by antibody titer correlates with kidney function parameters.
Li, Xin, Wei, Dong, Zhou, Zhanmei, Wang, Baoguo, Xu, Ya, Pan, Jie, Yang, Chunli, Lu, Jie, Qiu, Yurong   +8 more
openaire   +2 more sources

The value of PLA2R antigen and IgG subclass staining relative to anti-PLA2R seropositivity in the differential diagnosis of membranous nephropathy [PDF]

, 2023
Background The diagnostic performance of PLA2R and IgG subclass staining of kidney biopsies relative to anti-PLA2R seropositivity in the differentiation of primary and secondary membranous nephropathy (pMN, sMN) was examined.
Béla Iványi, Dóra Bajcsi, Éva Kemény, Péter Légrády, László Bitó, Sándor Turkevi-Nagy, Tibor Nyári, György Ábrahám   +7 more
core   +2 more sources

Clinical usefulness of anti-M-type phospholipase-A-receptor antibodies in patients with membranous nephropathy and the comparison of three quantification methods

Immunological Medicine, 2020
Associations between anti-M-type phospholipase A2 receptor (PLA2R) antibodies and disease activity and prognosis have been suggested in primary membranous nephropathy (MN); however, more evidence is needed.
Yasuhiro Katsumata, Yuko Okamoto, Takahito Moriyama, Rina Moriyama, Manabu Kawamoto, Masanori Hanaoka, Keiko Uchida, Kosaku Nitta, Masayoshi Harigai   +8 more
doaj   +1 more source

Anti-PLA2R antibody positivity in adult minimal change disease with tuberculosis co-infection: A case report. [PDF]

Medicine (Baltimore)
Rationale: Anti-phospholipase A2 receptor (PLA2R) antibody is a highly specific serological marker for primary membranous nephropathy, with a detection rate of <2% in minimal change disease (MCD). This case represents the first report of PLA2R-positive adult MCD complicated by active pulmonary tuberculosis ...
Chen X, Li N, Yang Q, Ling H, Yin H.
europepmc   +3 more sources

Relationship between renal tissues phospholipase A2 receptor and its serum antibody and clinical condition and prognosis of idiopathic membranous nephropathy: a meta-analysis

BMC Nephrology, 2019
Objective To investigate the correlation of M-type phospholipase A2 receptor (PLA2R) expression and serum anti-PLA2R antibody with the clinical parameters and prognosis of patients with idiopathic membranous nephropathy (IMN). Methods A literature search
Dan Dong, Ting-ting Fan, Ying-ying Wang, Lu Zhang, Li Song, Li Zhang   +5 more
doaj   +1 more source

Anti-PLA2R antibody in primary and secondary forms of membranous glomerulopathy [PDF]

, 2023
INTRODUÇÃO: A glomerulopatia membranosa (GNM) é considerada a principal causa de síndrome nefrótica em adultos. A maioria dos casos é considerada primária, mas cerca de 20-30% das GNM são secundárias a uma condição clínica subjacente, como neoplasias ...
Gazeta, Cristina do Amaral [UNIFESP]
core  

The optimal anti-phospholipase A2 receptor cutoff for the diagnosis of idiopathic membranous nephropathy: a single-center retrospective study [PDF]

The Korean Journal of Internal Medicine, 2022
Background/Aims Anti-phospholipase A2 receptor (PLA2R) autoantibody is the main biomarker of idiopathic membranous nephropathy (IMN). We aimed to find a new cutoff value of anti-PLA2R for patients with IMN and to explore the relevance between this ...
Chaofan Li, Ping Li, Wenkai Guo, Lei Chen, Jiatong Li, Rong Wang, Bing Chen   +6 more
doaj   +1 more source

Prognostic value of PLA2R autoimmunity detected by measurement of anti-PLA2R antibodies combined with detection of PLA2R antigen in membranous nephropathy: A single-centre study over 14 years. [PDF]

, 2017
INTRODUCTION:Clinical course of membranous nephropathy (MN) is difficult to predict. Measurement of circulating anti-PLA2R autoantibodies (PLA2R-Ab) and detection in immune deposits of PLA2R antigen (PLA2R-Ag) are major advances in disease understanding.
Isabelle Brocheriou (3812980), Franck Pourcine, Pierre Ronco, Marine Cachanado (3812983), Fabrice Mihout (3812971), Ronco, Pierre, Mihout, Fabrice, Brocheriou, Isabelle, Karine Dahan, Hanna Debiec, Karine Dahan (3812974), Pierre Ronco (534582), Isabelle Brocheriou, Cachanado, Marine, Pourcine, Franck, Franck Pourcine (3812968), Dahan, Karine, Marine Cachanado, Fabrice Mihout, Debiec, Hanna, Hanna Debiec (3812977), Dahan Karine, Mihout Fabrice, Pourcine Franck, Brocheriou Isabelle, Ronco Pierre, Cachanado Marine, Debiec Hanna   +27 more
core   +1 more source

Anti-phospholipase A2 receptor antibody levels at diagnosis predicts outcome of TAC-based treatment for idiopathic membranous nephropathy patients

BMC Nephrology, 2022
Background Idiopathic membranous nephropathy (iMN) is recognized as an organ-specific autoimmune disease, mainly caused by anti-PLA2R antibody. This study aimed to study between anti-PLA2R antibody level at diagnosis and the response to tacrolimus (TAC ...
Bihua Wang, Zhidan Zhu, Feng Huang, Haowen Huang, Luxia Tu, Ying Wang, Linfeng Zheng, Jing Zhou, Xin Wei   +8 more
doaj   +1 more source