Results 71 to 80 of about 3,430 (196)

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, Volume 9, Issue 9, September 2025.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Time-resolved fluoroimmunoassay improves sensitivity in the diagnosis of primary membranous nephropathy with low phospholipase A2 receptor antibody titer

Scientific Reports
To evaluate the diagnostic utility of time-resolved fluoroimmunoassay (TRFIA) for detecting serum anti-Phospholipase A2 Receptor (PLA2R) antibodies, specifically the IgG (PLA2R-IgG) and IgG4 subclass (PLA2R-IgG4).
Zhenling Deng, Yuanlin Qu, Yuting Liu, Tianyu Zheng, Yueming Gao, Biao Huang, Yue Wang, Danxia Zheng   +7 more
doaj   +1 more source

Serum phospholipase A2 receptor antibody is associated with thrombogenesis in patients with idiopathic membranous nephropathy

Kidney & Blood Pressure Research
Introduction: Patients with idiopathic membranous nephropathy (IMN) are particularly susceptible to thromboembolism (TE). The phospholipase A2 receptor (PLA2R) antibody (Ab) has been indicated to work as an independent risk predictor for venous TE in IMN.
Qinling Zhang, Guiling Liu
doaj   +1 more source

CARI Guidelines Commentary on the KDIGO Clinical Practice Guideline for the Management of Glomerular Diseases

Nephrology, Volume 30, Issue 9, September 2025.
ABSTRACT Aim The KDIGO 2021 Glomerular Disease Guidelines provide updated recommendations on the management of glomerular diseases (GD), with substantial advances made in diagnosis, treatment, and improvement of outcomes for people with GD. Methods The Caring for Australians and New Zealanders with kidney Impairment (CARI) Guidelines commentary ...
Bhadran Bose, Simon A. Carter, Mia E. Abdy, Nicole Scholes‐Robertson, Ieyesha Roberts, Tze Liang Goh, Vincent Lee, Emily See, Helen Coolican, Vanessa Cullen, Min Jun, Rathika Krishnasamy, Kelly Lambert, Jonathan Craig, Casey Light, Thu Nguyen, Carla Scuderi, David J. Tunnicliffe, Andrea K. Viecelli, Vincent Lee, Emily See, Helen Coolican, Vanessa Cullen, Min Jun, Kelly Lambert, Jonathan Craig, Casey Light, Thu Nguyen, Carla Scuderi   +28 more
wiley   +1 more source

Prevalence of Enhanced Granular Expression of Thrombospondin Type-1 Domain-Containing 7A in the Glomeruli of Japanese Patients with Idiopathic Membranous Nephropathy. [PDF]

PLoS ONE, 2015
Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults. Autoantibodies against M-type phospholipase A2 receptor (PLA2R) and thrombospondin type-1 domain-containing 7A (THSD7A), which mainly belong to the IgG4 subclass, were ...
Takamasa Iwakura, Naro Ohashi, Akihiko Kato, Satoshi Baba, Hideo Yasuda   +4 more
doaj   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, Volume 11, Issue 2, Page 89-104, June 2025.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

Analysis of Differentially Expressed Proteins Involved in Shrimp and Crab Allergies

Journal of Clinical Laboratory Analysis, Volume 39, Issue 12, June 2025.
Using proteomics techniques, we identified 90 differentially expressed proteins in children with shrimp and crab allergies compared to normal controls, with 82 upregulated and 8 downregulated proteins. Validation of MRC2 upregulation by ELISA in allergic patients highlights the potential role of this protein in the allergic response.
Ruhong Tan, Xiwen Wei, Jiacheng Zhong, Yuanbin Wang, Qing Yu   +4 more
wiley   +1 more source

Autoantibodies against phospholipase A2 receptor in Korean patients with membranous nephropathy. [PDF]

PLoS ONE, 2013
The data were presented in abstract form at the 45(th) meeting of the American Society of Nephrology, October 30-November 04 2012, San Diego, CA, USA. Circulating autoantibodies against M-type phospholipase A2 receptor (PLA2R) are important pathogenic ...
Yun Jung Oh, Seung Hee Yang, Dong Ki Kim, Shin-Wook Kang, Yon Su Kim   +4 more
doaj   +1 more source

Managing Pulmonary Embolism Associated With Renal Vein Thrombosis During Nephrotic Syndrome: Usefulness of Rivaroxaban Level Monitoring

Respirology Case Reports, Volume 13, Issue 6, June 2025.
This clinical experience confirms the efficacy and safety of rivaroxaban for the treatment of thromboembolic events in patients with nephrotic syndrome but also suggests the usefulness of monitoring drug levels when the embolic event occurs during a period of significant proteinuria, such as at the time of nephrotic syndrome diagnosis.
Gabriele De Masi De Luca, Alessandro Naticchia, Zefferino Palamà, Carlo Maisto, Simonetta Longo, Marzia Colopi, Francesca Barba, Giuseppe De Masi De Luca, Stefania Marazia, Silvio Romano, Luigi Sciarra   +10 more
wiley   +1 more source

Outcome of patients with PLA2R-related PMN.

, 2017
Outcome of patients with PLA2R-related PMN.
Isabelle Brocheriou (3812980), Franck Pourcine (3812968), Marine Cachanado (3812983), Fabrice Mihout (3812971), Karine Dahan (3812974), Pierre Ronco (534582), Hanna Debiec (3812977)   +6 more
core   +1 more source