Results 71 to 80 of about 3,877 (197)

Serum phospholipase A2 receptor antibody is associated with thrombogenesis in patients with idiopathic membranous nephropathy

Kidney & Blood Pressure Research
Introduction: Patients with idiopathic membranous nephropathy (IMN) are particularly susceptible to thromboembolism (TE). The phospholipase A2 receptor (PLA2R) antibody (Ab) has been indicated to work as an independent risk predictor for venous TE in IMN.
Qinling Zhang, Guiling Liu
doaj   +1 more source

Presence of M-type Phospholipase A2 Receptor Antibody in Membranous Nephropathy

Turkish Journal of Nephrology, 2020
Objective: The presence of autoantibodies against M-type phospholipase A2 receptor (anti-PLA2R) is a characteristic of idiopathic membranous nephropathy (IMN).
Özgür Akın Oto, Halil Yazıcı, Yaşar Çalışkan, Ayşe Serra Artan, Mehmet Şükrü Sever, Egemen Cebeci, Savaş Öztürk, Aydın Türkmen   +7 more
doaj   +1 more source

Phospholipase A2 Receptor Antibodies and Clinical Prognosis in Patients with Idiopathic Membranous Nephropathy: An Updated Systematic Review and Meta-Analysis

Kidney & Blood Pressure Research, 2023
Background: Idiopathic membranous nephropathy (IMN) is the most common form of primary nephrotic syndrome in adults. Antibodies against the M-type phospholipase A2 receptor (PLA2R-ab) are considered as diagnostic biomarkers of IMN.
Jialing Zhang, Zhengjia Fan, Peixin Wang, Ai-Hua Zhang   +3 more
doaj   +1 more source

Membranous nephropathy PLA2R+ associated with Chagas disease

Autopsy and Case Reports, 2015
Chagas disease (CD) - a tropical parasitic disease caused by the protozoan Trypanosoma cruzi - is a major health problem in Latin America. The immune response against the parasite is responsible for chronic CD lesions. Currently, there are no reports of an association between CD and membranous nephropathy (MN).
José Cândido Caldeira Xavier-Júnior, Vanessa dos Santos Silva, Rosa Marlene Viero   +2 more
openaire   +3 more sources

A membranous nephropathy variant mimicking minimal change disease

The Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.
Abstract This study characterizes a novel disease pattern of membranous nephropathy (MN) that exhibits overlapping clinicopathological features with minimal change disease (MCD), termed ‘MCD‐like MN’. Patients with histologically confirmed MN showing sparse and segmental subepithelial electron‐dense deposits (EDD) but clinically resembling MCD were ...
Chuqi Pan, Silin Xiang, Mengya Jiang, Yuan Li, Biao Huang, Tian Ye, Yuanyuan Du, Xuanli Tang, Yuan Yuan   +8 more
wiley   +1 more source

IgG4‐Related Bilateral Renal Enlargement With Mild Dysfunction in a Patient With Non‐IgG4 Ulcerative Colitis: A Case Report

Case Reports in Medicine, Volume 2026, Issue 1, 2026.
Immunoglobulin G4–related disease (IgG4‐RD) is a chronic fibroinflammatory disorder affecting multiple organs, including the kidneys. Ulcerative colitis (UC) is an immune‐mediated colonic disease. Their coexistence is uncommon, especially when UC is not IgG4 associated.
Liping Xu, Xianfa Xuan, Yiqin Zhang, Pengcheng Yu, Semonti Nandi   +4 more
wiley   +1 more source

Always Consider a Repeat Kidney Biopsy: Acute Interstitial Nephritis Soon After Membranous Nephropathy

Case Reports in Nephrology, Volume 2026, Issue 1, 2026.
Introduction The heterogeneity of membranous nephropathy is well described in the literature, and its clinical course and response to treatment vary. Similarly, acute interstitial nephritis (AIN) can present in unexpected and unusual ways and should always be considered within the differential diagnosis of worsening renal function.
Jarrad Hopkins, James Nolan, Maleeka Ladhani, Chiang Lee, Poulami Jha   +4 more
wiley   +1 more source

Glomerulonephrite extramembraneuse anti-PLA2R+: 39 ans d’activite sans insuffisance renale!

, 2019
Objectif: Rapporter un cas de Glomérulonéphrite extra membraneuse anti-PLA2R+ évoluant depuis 39 ans, sans insuffisance rénale. Observation : Le diagnostic histologique de syndrome néphrotique à lésions glomérulaires minimes fut posé en 1980 chez une ...
Djibril, M.A., Tsevi, Y.M., Aydin, S, Jadoul, M, Djagadou, K.A., Nemi, K.D.   +5 more
core   +1 more source

Can use of the serum anti-PLA2R antibody negate the need for a renal biopsy in primary membranous nephropathy?

, 2023
Background Since the emergence of the anti-PLA2R antibody (PLA2R-Ab) test, nephrology practice has not changed dramatically, with most nephrologists still relying on a kidney biopsy to diagnose membranous nephropathy.
Vilma Rautemaa, Smith, A, Smith, Alison, Durga Kanigicherla, Brenchley, Paul; id_orcid, Hamilton, P, Paul Brenchley, Brenchley, P, Rautemaa, Vilma, Patrick Hamilton, Rautemaa, V, Ragy, O, Alison Smith, Hamilton, Patrick, Kanigicherla, Durga, Ragy, Omar, Kanigicherla, D, Omar Ragy   +17 more
core   +1 more source

Diagnostic Complexity in Differentiating Between Primary and Secondary Anti‐PLA2R–Positive Membranous Nephropathy in a Patient With Laryngeal Squamous Cell Carcinoma

Case Reports in Nephrology, Volume 2026, Issue 1, 2026.
Introduction The association between membranous nephropathy (MN) and malignant neoplasms has been extensively studied in recent decades and is well established in the literature. Although PLA2R is the main target antigen in primary MN, there remain uncertainties regarding a possible connection between malignancy and anti‐PLA2R positivity.
Fabiano Bichuette Custodio, Laura Penna Rocha, Luciana Botta Ribeiro, Marlene Antônia dos Reis, Juliana Reis Machado, Poorani Gurumallesh Prabu   +5 more
wiley   +1 more source