Results 31 to 40 of about 5,277,200 (190)
Mechanosensitive localization of Diversin highlights its function in vertebrate morphogenesis and planar cell polarity. [PDF]
Biol OpenVelayudhan SS, Chu CW, Itoh K, Sokol SY.
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Biology Open, 2021 Coordinated polarization of cells in the tissue plane, known as planar cell polarity (PCP), is associated with a signaling pathway critical for the control of morphogenetic processes. Although the segregation of PCP components to opposite cell borders is
Pamela Mancini +2 more
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Nature Communications, 2021 Ommatidial rotation in the Drosophila eye is a regulated process and a Planar Cell Polarity (PCP) cell motility model. Here, the authors show that tissue fluidity via junctional remodeling, as regulated by the PCP effector kinase Nemo, is critical for ...
Nabila Founounou +5 more
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PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration. [PDF]
PLoS Genetics, 2016 The planar cell polarity (PCP) pathway is a cell-contact mediated mechanism for transmitting polarity information between neighboring cells. PCP "core components" (Vangl, Fz, Pk, Dsh, and Celsr) are essential for a number of cell migratory events ...
Crystal F Davey +2 more
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Conserved and Divergent Principles of Planar Polarity Revealed by Hair Cell Development and Function
Frontiers in Neuroscience, 2021 Planar polarity describes the organization and orientation of polarized cells or cellular structures within the plane of an epithelium. The sensory receptor hair cells of the vertebrate inner ear have been recognized as a preeminent vertebrate model ...
Michael R. Deans, Michael R. Deans
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Planar cell polarity in the larval epidermis of Drosophila and the role of microtubules [PDF]
Open Biology, 2020 We investigate planar cell polarity (PCP) in the Drosophila larval epidermis. The intricate pattern of denticles depends on only one system of PCP, the Dachsous/Fat system.
Stefano Pietra +3 more
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Frontiers in Cell and Developmental Biology, 2021 During development, sensory hair cells (HCs) in the cochlea assemble a stereociliary hair bundle on their apical surface with planar polarized structure and orientation.
Andre Landin Malt +8 more
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Biology Open, 2015 The vertebrate neural tube forms as a result of complex morphogenetic movements, which require the functions of several core planar cell polarity (PCP) proteins, including Vangl2 and Prickle.
Olga Ossipova +2 more
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Wnt proteins can direct planar cell polarity in vertebrate ectoderm
eLife, 2016 The coordinated orientation of cells across the tissue plane, known as planar cell polarity (PCP), is manifested by the segregation of core PCP proteins to different sides of the cell.
Chih-Wen Chu, Sergei Y Sokol
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A novel, PCP-dependent tissue organising principle coordinating morphogenesis between embryonic skin epidermal layers. [PDF]
J Anat‘Outside‐in’ expression of Fz6 across multiple layers of mouse embryo epidermis is connected to Fz6 asymmetry in the basal layer plane. Fz6 loss‐of‐function correlated with failure to: coordinate axial bias of cell long axis orientation across epidermal layers, switch axial cell long axis orientation during suprabasal layer development and establish ...
Formstone CJ.
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