Results 31 to 40 of about 1,205 (188)
Subcellular targeting and biosynthesis of cyclotides in plant cells [PDF]
American Journal of Botany, 2011 • Premise of the study: The cyclotide kalata B1 is found in the leaves of Oldenlandia affinis and is a potent insecticidal and nematocidal molecule. This peptide is cleaved from a precursor protein, Oak1, and ligation of the N‐ and C‐termini occurs to form a continuous peptide backbone. The subcellular location of the excision and cyclization reactions
Conlan, Brendon +3 more
openaire +3 more sources
The involvement of cyclotides in mutual interactions of violets and the two-spotted spider mite
Scientific Reports, 2022 Plants employ different chemicals to protect themselves from herbivory. These defenses may be constitutive or triggered by stress. The chemicals can be toxic, act as repellents, phagosuppressants and/or phago-deterrents.
Blazej Slazak +11 more
doaj +1 more source
Cyclotides Isolated From Violet Plants of Cameroon Are Inhibitors of Human Prolyl Oligopeptidase
Frontiers in Pharmacology, 2021 Traditional medicine and the use of herbal remedies are well established in the African health care system. For instance, Violaceae plants are used for antimicrobial or anti-inflammatory applications in folk medicine.
Jasmin Gattringer +5 more
doaj +1 more source
PLoS ONE, 2014 Cyclotides are a family of plant-derived proteins that are characterized by a cyclic backbone and a knotted disulfide topology. Their cyclic cystine knot (CCK) motif makes them exceptionally resistant to thermal, chemical, and enzymatic degradation ...
Sungkyu Park +2 more
doaj +1 more source
Frontiers in Plant Science, 2017 Cyclotides are a family of plant proteins that are characterized by a cyclic backbone and a knotted disulfide topology. Their cyclic cystine knot (CCK) motif makes them exceptionally resistant to thermal, chemical, and enzymatic degradation.
Sungkyu Park +7 more
doaj +1 more source
Frontiers in Pharmacology, 2017 Cyclotides are plant derived, cystine-knot stabilized peptides characterized by their natural abundance, sequence variability and structural plasticity. They are abundantly expressed in Rubiaceae, Psychotrieae in particular.
Mohsen Fahradpour +8 more
doaj +1 more source
مجلة مركز بحوث التقنيات الاحيائية, 2021 Traditionally medicinal plants are used for its potential chemotherapeutic action and for safety upon the continued use of these plants. Many medicinal plants are containing great bioactive components that reported to preventive and therapeutic role ...
ٍSura A. Saud
doaj +1 more source
Cytotoxic Cyclotides from Anchietea pyrifolia, a South American Plant Species
, 2022 Cyclotides are mini-proteins with potent bioactivities and outstanding potential for agricultural and pharmaceutical applications. More than 450 different plant cyclotides have been isolated from six angiosperm families. In Brazil, studies involving this
Larissa Costa de Almeida (13548497) +10 more
core +1 more source
Plant-Derived Antimicrobial Peptides as Potential Antiviral Agents in Systemic Viral Infections
Pharmaceuticals, 2021 Numerous studies have led to a better understanding of the mechanisms of action of viruses in systemic infections for the development of prevention strategies and very promising antiviral therapies.
Nour Mammari +5 more
doaj +1 more source
RaPID Selection of Backbone Macrocyclic Peptides Targeting Akt2
Angewandte Chemie, Volume 138, Issue 21, 18 May 2026.Backbone macrocyclic peptide library (BMP) library was screened against Akt2 via RaPID to discover potent BMPPakti‐3 (IC50 = 34 nM). ABSTRACT Backbone‐cyclic peptides (BMPs) are an attractive class of molecules appeared in diverse natural bioactive products. However, mRNA display technology coupled with ribosomal synthesis is intrinsically inapplicable
Koki Shinbara +4 more
wiley +2 more sources