Results 11 to 20 of about 28,516 (205)

Contribution of plasminogen activation towards the pathogenic potential of oral streptococci. [PDF]

open access: yesPLoS ONE, 2010
Oral streptococci are a heterogeneous group of human commensals, with a potential to cause serious infections. Activation of plasminogen has been shown to increase the virulence of typical human pathogenic streptococci such as S. pneumoniae.
Andreas Itzek   +6 more
doaj   +1 more source

Proteolytic enzyme and adiponectin receptors as potential targets for COVID-19 therapy

open access: yesКардиоваскулярная терапия и профилактика, 2021
The coronavirus disease 2019 (COVID-19) pandemic requires not only the creation of vaccines to prevent the spread of the disease, but also the development of novel drugs aimed at reducing viral load, suppressing an excessive immune response and ...
K. A. Rubina   +5 more
doaj   +1 more source

Repeat reteplase therapy in a patient with recurrent prosthetic tricuspid valve thrombosis after trido multiple valve replacement

open access: yesAnnals of Cardiac Anaesthesia, 2020
Prosthetic valve thrombosis (PVT) is a rare but life-threatening complication. It has an incidence of 6.1% in developing countries and 0.3%–1.3% in developed countries.
Hasan Haghaninejad   +2 more
doaj   +1 more source

Location, location, location: Fibrin, cells, and fibrinolytic factors in thrombi

open access: yesFrontiers in Cardiovascular Medicine, 2023
Thrombi are heterogenous in nature with composition and structure being dictated by the site of formation, initiating stimuli, shear stress, and cellular influences. Arterial thrombi are historically associated with high platelet content and more tightly
Anuj Narwal   +2 more
doaj   +1 more source

Fibrinolysis and bleeding of unknown cause

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Patients with bleeding of unknown cause (BUC) present with a variety of mild to moderate bleeding symptoms, but no hemostatic abnormalities can be found. Hyperfibrinolysis is rarely evaluated as the underlying cause for bleeding in clinical practice, and
Dino Mehic   +3 more
doaj   +1 more source

Assessment of serum levels of monocyte chemoattractant protein 1 (MCP 1) in patients with periodontitis and atherosclerotic cardiovascular disease

open access: yesJournal of Baghdad College of Dentistry, 2022
Background: Monocyte chemotactic protein-1 (MCP-1) is a chemokine expressed by inflammatory and endothelial cells. It has a crucial role in initiating, regulating, and mobilizing monocytes to active sites of periodontal inflammation.
Safa A Hamad , Maha S Mahmood
doaj   +1 more source

The X-ray Crystal Structure of Full-Length Human Plasminogen

open access: yesCell Reports, 2012
Plasminogen is the proenzyme precursor of the primary fibrinolytic protease plasmin. Circulating plasminogen, which comprises a Pan-apple (PAp) domain, five kringle domains (KR1-5), and a serine protease (SP) domain, adopts a closed, activation-resistant
Ruby H.P. Law   +13 more
doaj   +1 more source

Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. [PDF]

open access: yes, 1989
Human fetal development depends on the embryo rapidly gaining access to the maternal circulation. The trophoblast cells that form the fetal portion of the human placenta have solved this problem by transiently exhibiting certain tumor-like properties ...
Cui, TY   +7 more
core   +3 more sources

Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]

open access: yes, 2017
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila   +5 more
core   +2 more sources

Home - About - Disclaimer - Privacy