An antibody that targets cell-surface glucose-regulated protein-78 inhibits expression of inflammatory cytokines and plasminogen activator inhibitors by macrophages. [PDF]
Gunner CB +6 more
europepmc +1 more source
CLINICAL SCIENCES Glutathione and Glutathione S-Transferases as Early Markers for Ovarian Carcinomas: Case Series [PDF]
Aim. To determine the activity of glutathione (GSH) and concentrations of glutathione S-transferases (GST), urokinase type plasminogen activator (uPA), and plasminogen activator inhibitor type 1 (PAI-1), and to evaluate their diagnostic and prognostic ...
Andreja Ambrioviae Ristov +8 more
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Design, synthesis, and biological evaluation of non-symmetric smal [PDF]
Plasminogen activator inhibitor-1 (PAI-1) is a member of the serpin family of proteins, a primary inhibitor of both tissue-type and urokinase-type plasminogen activators in plasma, and is a well-established risk factor in various disease conditions ...
Anumala, Himabindu
core +1 more source
Acute aortic occlusion after microendoscopic laminectomy in a patient with lumbar spinal stenosis: A case report. [PDF]
Inoue H +6 more
europepmc +1 more source
Suprachoroidal haemorrhage (SCH) drainage using suprachoroidal tissue plasminogen activator (t-PA) after complicated cataract extraction (two-staged procedure): early intervention could mean better vision. [PDF]
Akram H, Dowlut MS, Chandra A.
europepmc +1 more source
Single-chain urokinase-type plasminogen activator (scu-PA) is cleaved by thrombin, resulting in an inactive molecule called thrombin-cleaved two-chain urokinase-type plasminogen activator (tcu-PA/T). There is no knowledge about cell-mediated inactivation of scu-PA. We have studied whether scu-PA bound to cultured human umbilical vein endothelial cells (
Braat, E.A.M. +4 more
openaire +3 more sources
Angiotensin-Converting Enzyme Inhibitors and Other Medications Associated With Angioedema. [PDF]
Landry L +8 more
europepmc +1 more source
SummaryOvine prolactin (0.5 mg) was incubated for 2 hours at 37.5°C with human plasminogen with and without e-aminocaproic acid (EACA). Fibrinolytic activity (FA) and prolactin-inactivating activity (PIA) were increased by streptokinase (SK). EACA at 0.026 M (5.0 mg) and 0.26 M (50.0 mg) increased FA but did not increase PIA.
T F, HOPKINS, J, MEITES
openaire +2 more sources
The Effect of Protease-Activated Receptor-1 (PAR-1) Inhibition on Endothelial-Related Biomarkers in Patients with Coronary Artery Disease. [PDF]
Nilsen DWT +9 more
europepmc +1 more source
thesisMany haemorrhagic complications have been attributed to increased intravascular fibrinolytic activity. The degradation products resulting from fibrinolysis have been shown to interfere in fibrin polymerization and have been observed in defective ...
Maxwell, Molly Tucker
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