Results 41 to 50 of about 7,167 (241)
Cells, 2020 Cotransplantation of mesenchymal stem cells (MSCs) with hematopoietic stem cells (HSCs) has been widely reported to promote HSC engraftment and enhance marrow stromal regeneration.
Yu-Hee Kim +7 more
doaj +1 more source
Frontiers in Neurology, 2021 Heparin-binding growth-associated molecule (pleiotrophin) is a neurite outgrowth-promoting secretory protein that lines developing fiber tracts in juvenile CNS (central nervous system).
Natalia Kulesskaya +6 more
doaj +1 more source
Effect of trophic factor on single vascular insult induced amyloid accumulation with AD mice [PDF]
Alzheimers DementAbstract Background Alzheimer's disease (AD) is always presented as mixed dementia including vascular pathology. It is very often seen in elderly population that subjects with high vascular risk factors is associated white matter changes leading to cognitive decline.
Pushpam M, Hussain R, Diwakar L.
europepmc +2 more sources
Relationship Between Serum Concentrations of the Growth Factor Pleiotrophin and Pleiotrophin-Positive Tumors [PDF]
JNCI: Journal of the National Cancer Institute, 1998 Growth factors produced by tumor cells are essential for tumor expansion and may be useful in monitoring tumor progression or therapeutic efficacy if the factors are released into the circulation. In this study, we measured serum levels of pleiotrophin, a secreted heparin-binding growth and angiogenesis factor, in mice bearing human tumor xenografts to
B, Souttou +7 more
openaire +2 more sources
A Pleiotrophin C-terminus peptide induces anti-cancer effects through RPTPβ/ζ
Molecular Cancer, 2010 Background Pleiotrophin, also known as HARP (Heparin Affin Regulatory Peptide) is a growth factor expressed in various tissues and cell lines. Pleiotrophin participates in multiple biological actions including the induction of cellular proliferation ...
Diamantopoulou Zoi +6 more
doaj +1 more source
Pleiotrophin serum level and metastasis occurrence in breast cancer patients. [PDF]
Breast DisBACKGROUND: Breast cancer (BC) cases in Makassar, Indonesia, are on the rise, with 2723 cases recorded in 2018. Tumor cells in the blood indicate metastasis, emphasizing the need for early diagnosis and monitoring.
Ikhlas M +7 more
europepmc +2 more sources
Pleiotrophin over-expression provides trophic support to dopaminergic neurons in parkinsonian rats
Molecular Neurodegeneration, 2011 Background Pleiotrophin is known to promote the survival and differentiation of dopaminergic neurons in vitro and is up-regulated in the substantia nigra of Parkinson's disease patients.
Pitossi Fernando J +6 more
doaj +1 more source
New molecular mediators in tumor angiogenesis [PDF]
, 2007 Angiogenesis is essential for tumor growth and progression. It has been demonstrated that tumor growth beyond a size 1 to 2 mm3 requires the induction of new vessels.
Beecken, Wolf-Dietrich +2 more
core +1 more source
Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degeneration [PDF]
, 2014 Introduction : The degenerate intervertebral disc (IVD) becomes innervated by sensory nerve fibres, and vascularised by blood vessels. This study aimed to identify neurotrophins, neuropeptides and angiogenic factors within native IVD tissue and to ...
Binch, Abbie L.A. +6 more
core +2 more sources
Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma
Pharmaceuticals, 2011 RNA interference (RNAi) allows the specific knockdown of tumor relevant genes. To induce RNAi, the delivery of small interfering RNAs (siRNAs) is of crucial importance. This is particularly challenging for their therapeutic applications in vivo.
Achim Aigner +3 more
doaj +1 more source