Results 61 to 70 of about 7,167 (241)
Frontiers in Immunology, 2020 In a previous study, we have reported an increased plasma midkine (MK) and pleiotrophin (PTN) concentrations in patients with systemic lupus erythematosus (SLE) and the increase in MK and PTN associated with inflammatory cytokines interleukin (IL)-17 ...
Peng Wang +11 more
doaj +1 more source
Methylcobalamin facilitates collateral sprouting of donor axons and innervation of recipient muscle in end-to-side neurorrhaphy in rats. [PDF]
PLoS ONE, 2013 Using ulnar nerve as donor and musculocutaneous nerve as recipient we found earlier that end-to-side neurorrhaphy resulted in weak functional reinnervation after lengthy survival.
Wen-Chieh Liao +3 more
doaj +1 more source
Targeting self-renewal pathways in myeloid malignancies [PDF]
, 2013 A fundamental property of hematopoietic stem cells (HSCs) is the ability to self-renew. This is a complex process involving multiple signal transduction cascades which control the fine balance between self-renewal and differentiation through ...
Copland, M., Sands, W.A., Wheadon, H.
core +2 more sources
Proteoglycans and neuronal migration in the cerebral cortex during development and disease [PDF]
, 2015 Chondroitin sulfate proteoglycans and heparan sulfate proteoglycans are major constituents of the extracellular matrix and the cell surface in the brain. Proteoglycans bind with many proteins including growth factors, chemokines, axon guidance molecules,
Nobuaki Maeda
core +2 more sources
Neuroscience Insights, 2023 Chondroitin sulfate proteoglycans (CSPGs), one of the major extracellular matrix components of the glial scar that surrounds central nervous system (CNS) injuries, are known to inhibit the regeneration of neurons.
Somnath J Gupta +3 more
semanticscholar +1 more source
A Comparative Analysis of Erythropoietin and Carbamoylated Erythropoietin Proteome Profiles
Life, 2021 In recent years, erythropoietin (EPO) has emerged as a useful neuroprotective and neurotrophic molecule that produces antidepressant and cognitive-enhancing effects in psychiatric disorders.
Neeraj K. Tiwari +3 more
doaj +1 more source
Non-Canonical Thinking for Targeting ALK-Fusion Onco-Proteins in Lung Cancer. [PDF]
, 2017 Anaplastic lymphoma kinase (ALK) gene rearrangements have been identified in lung cancer at 3-7% frequency, thus representing an important subset of genetic lesions that drive oncogenesis in this disease. Despite the availability of multiple FDA-approved
Bivona, Trever G +2 more
core +3 more sources
Gene Expression Profiling in Familial Adenomatous Polyposis Adenomas and Desmoid Disease [PDF]
, 2007 Gene expression profiling is a powerful method by which alterations in gene expression can be interrogated in a single experiment. The disease familial adenomatous polyposis (FAP) is associated with germline mutations in the APC gene, which result in ...
Nikola A Bowden +2 more
core +1 more source
Nature CommunicationsAstrocytes are closely linked to depression, and the prefrontal cortex (PFC) is an important brain region involved in major depressive disorder (MDD).
Dongmei Chi +11 more
semanticscholar +1 more source
Journal of Immunological Research, 2023 Midkine (MK) and pleiotrophin (PTN) belong to the same family of cytokines. They have similar sequences and functions. Both have important roles in cellular proliferation, tumors, and diseases. They regulate and are expressed by some immune cells.
E. Said +15 more
semanticscholar +1 more source