Results 201 to 210 of about 53,758 (224)
International Journal of Cosmetic Science, Volume 48, Issue 1, Page 186-199, February 2026.Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier +9 more
wiley +1 more source
Journal of Neurochemistry, Volume 170, Issue 2, February 2026.When mitochondria are damaged by MPP+, they produce excess reactive oxygen species (ROS) and release zinc (Zn2+) inside the cell. This surge in zinc overwhelms lysosomes—the cell's major zinc‐buffering organelles—causing their membranes to break down. Leaking lysosomal enzymes then trigger neuronal death. Treatments that reduce ROS, bind zinc, or block
Hyun‐Seung Lee +5 more
wiley +1 more source
Glial cells in the heart: Implications for their roles in health and disease
The Journal of Physiology, Volume 604, Issue 4, Page 1531-1546, 15 February 2026.Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya +2 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Mechanistic pathways of PIK3R1 in skin aging and rejuvenation were analyzed by bioinformatics approach and Gene Expression Omnibus database. Compared with young skin, PIK3R1 was differentially expressed in aged and IPL rejuvenated skin. Coexpression and network analyses revealed that PIK3R1 jointly participated in skin aging and rejuvenation via PI3K ...
Zhike Zhou +8 more
wiley +1 more source
Biochemical and Physiological Effects of Galanin in Health and Disease
The FASEB Journal, Volume 40, Issue 2, 31 January 2026.Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles +3 more
wiley +1 more source
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Nature Methods, 2010
Retroviral marking of single human embryonic stem cells shows that cultures of these cells contain subpopulations with distinct functional properties.
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Retroviral marking of single human embryonic stem cells shows that cultures of these cells contain subpopulations with distinct functional properties.
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2013
The molecular and phenotypic irreversibility of mammalian cell differentiation was a fundamental principle of developmental biology at least until the 1980s, despite numerous reports dating back to the 1950s of the induction of pluripotency in amphibian cells by nuclear transfer (NT).
Corey, Heffernan +6 more
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The molecular and phenotypic irreversibility of mammalian cell differentiation was a fundamental principle of developmental biology at least until the 1980s, despite numerous reports dating back to the 1950s of the induction of pluripotency in amphibian cells by nuclear transfer (NT).
Corey, Heffernan +6 more
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Nature, 2015
Stem cells self-renew and generate specialized progeny through differentiation, but vary in the range of cells and tissues they generate, a property called developmental potency. Pluripotent stem cells produce all cells of an organism, while multipotent or unipotent stem cells regenerate only specific lineages or tissues.
Alejandro, De Los Angeles +16 more
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Stem cells self-renew and generate specialized progeny through differentiation, but vary in the range of cells and tissues they generate, a property called developmental potency. Pluripotent stem cells produce all cells of an organism, while multipotent or unipotent stem cells regenerate only specific lineages or tissues.
Alejandro, De Los Angeles +16 more
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Nature Methods, 2009
A brief overview of methods for reprogramming to induced pluripotency and of the properties of induced pluripotent stem cells.
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A brief overview of methods for reprogramming to induced pluripotency and of the properties of induced pluripotent stem cells.
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