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Induction of Pluripotency

2013
The molecular and phenotypic irreversibility of mammalian cell differentiation was a fundamental principle of developmental biology at least until the 1980s, despite numerous reports dating back to the 1950s of the induction of pluripotency in amphibian cells by nuclear transfer (NT).
Corey, Heffernan   +6 more
openaire   +2 more sources

Frontiers of Pluripotency

2019
Humans develop from a unique group of pluripotent cells in early embryos that can produce all cells of the human body. While pluripotency is only transiently manifest in the embryo, scientists have identified conditions that sustain pluripotency indefinitely in the laboratory.
openaire   +2 more sources

Advances in Reprogramming to Pluripotency

Current Stem Cell Research & Therapy, 2015
Pluripotent stem cells (PSCs) derived from somatic cells represent a powerful experimental tool for investigating the molecular mechanisms underlying the disease phenotype; with prospects to advance medical therapies. They also have significant potential as a renewable source of autologous cells for cellular therapy.
Alateeq, Suad   +2 more
openaire   +5 more sources

Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency

Cell Stem Cell, 2021
Sabine Dietmann   +2 more
exaly  

Ground rules of the pluripotency gene regulatory network

Nature Reviews Genetics, 2017
Mo Li   +2 more
exaly  

Molecular coupling of Tsix regulation and pluripotency

Nature, 2010
Nicola Festuccia   +2 more
exaly  

Remodelling for pluripotency

Nature Reviews Molecular Cell Biology, 2010
Kim Baumann, Baumann Kim
exaly  

Deconstructing the pluripotency gene regulatory network

Nature Cell Biology, 2018
Mo Li   +2 more
exaly  

A bioinformatic assay for pluripotency in human cells

Nature Methods, 2011
Jeanne F Loring   +2 more
exaly  

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