Results 221 to 230 of about 62,870 (256)
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2013
The molecular and phenotypic irreversibility of mammalian cell differentiation was a fundamental principle of developmental biology at least until the 1980s, despite numerous reports dating back to the 1950s of the induction of pluripotency in amphibian cells by nuclear transfer (NT).
Corey, Heffernan +6 more
openaire +2 more sources
The molecular and phenotypic irreversibility of mammalian cell differentiation was a fundamental principle of developmental biology at least until the 1980s, despite numerous reports dating back to the 1950s of the induction of pluripotency in amphibian cells by nuclear transfer (NT).
Corey, Heffernan +6 more
openaire +2 more sources
2019
Humans develop from a unique group of pluripotent cells in early embryos that can produce all cells of the human body. While pluripotency is only transiently manifest in the embryo, scientists have identified conditions that sustain pluripotency indefinitely in the laboratory.
openaire +2 more sources
Humans develop from a unique group of pluripotent cells in early embryos that can produce all cells of the human body. While pluripotency is only transiently manifest in the embryo, scientists have identified conditions that sustain pluripotency indefinitely in the laboratory.
openaire +2 more sources
Advances in Reprogramming to Pluripotency
Current Stem Cell Research & Therapy, 2015Pluripotent stem cells (PSCs) derived from somatic cells represent a powerful experimental tool for investigating the molecular mechanisms underlying the disease phenotype; with prospects to advance medical therapies. They also have significant potential as a renewable source of autologous cells for cellular therapy.
Alateeq, Suad +2 more
openaire +5 more sources
Capture of Mouse and Human Stem Cells with Features of Formative Pluripotency
Cell Stem Cell, 2021Sabine Dietmann +2 more
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Ground rules of the pluripotency gene regulatory network
Nature Reviews Genetics, 2017Mo Li +2 more
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Control of ground-state pluripotency by allelic regulation of Nanog
Nature, 2012Maria-Elena Torres-Padilla
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Deconstructing the pluripotency gene regulatory network
Nature Cell Biology, 2018Mo Li +2 more
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A bioinformatic assay for pluripotency in human cells
Nature Methods, 2011Jeanne F Loring +2 more
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