Results 201 to 210 of about 83,579 (259)

Weighted Single‐Step GWAS Reveals Genetic Mechanisms Underlying Pregnancy Loss in Early Nellore Heifers

Animal Genetics, Volume 57, Issue 5, October 2026.
ABSTRACT Pregnancy loss (PL) affects reproductive efficiency in beef cattle, yet its genetic architecture remains poorly understood in Bos indicus populations. Here, PL was defined as failure from pregnancy diagnosis to calving, capturing a window approximately 60 days after the breeding season.
Flávia C. Bis, Nedenia Bonvino Stafuzza, Elisângela Chicaroni de Mattos, Angélica Simone Cravo Pereira, José Bento Sterman Ferraz, Fernando Baldi, Sabrina T. Amorim   +6 more
wiley   +1 more source

Generation and characterization of induced pluripotent stem cells from a patient with classic Fabry disease. [PDF]

Intractable Rare Dis Res
Li G, Luan J, Li Z, Yang Y, Shao C, Wang J, Han Z, Wang Q, Zhu Y, Yu C, Cui Y, Han J.   +11 more
europepmc   +1 more source

Brains for dementia research at 18: Commitment to impact the value of human post‐mortem tissue

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract The Brains for Dementia Research (BDR) project was established to provide high quality, neuropathologically characterized post‐mortem brain tissue from a cohort of participants longitudinally assessed for outcomes that are relevant for research in relation to dementia.
Keeley J. Brookes, Nicola Barnett, Johanna S. Jackson, Emma J Kidd, Debra J. Lett, Jillian Madine, Ben Middlehurst, Laura E. Palmer, Laura Parkkinen, Andrew C. Robinson, Rebecca Sims, Lindsey Sinclair, Alexandra Stolzing, Philip Tinkler, Claire Troakes, Lauren Walker, The BDR Collaborative, Alan Thomas, Patrick G. Kehoe   +18 more
wiley   +1 more source

High-throughput Phosphoproteomics Reveals the Role of Phosphorylation in Pluripotency and Phase Separation. [PDF]

Proteomics
Tang Y, Huang H, Wu T, Du J, Pang L, Yang H, Li H, Wei J, Ma Q.   +8 more
europepmc   +1 more source

Modulation of Endoplasmic Reticulum Stress via CEBPB: A Potential Molecular Link to Therapeutic Action in Substance Use Disorders

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
We identified endoplasmic reticulum (ER) stress modulation as a convergent transcription signature across fentanyl and multiple substance use disorder (SUD)‐relevant treatments. Key ER stress genes, including TRIB3, XBP1, and DDIT3, were downregulated, while CEBPB emerged as a shared upstream regulator linked to ER stress–related proteins.
Cheng Zhang, Hu Li, Ming‐Fen Ho
wiley   +1 more source

Cancer-Associated STAT3 Mutations Maintain ES Cell Self-Renewal Through Phosphorylation-Independent Mechanisms. [PDF]

Genes Cells
Akagi T, Nakamura S, Tamaru T, Ueda A, Yokota T.   +4 more
europepmc   +1 more source

Stem Cell and EV/sEV Strategies for Neuroimmune Niche Reprogramming in Selected CNS Disorders: Mechanisms, Engineered Delivery, and Translational Readiness

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Stem cell‐ and EV/sEV‐based interventions may reprogram the CNS neuroimmune niche by suppressing glial inflammation, enhancing trophic and synaptic support, stabilizing BBB communication, and improving metabolic resilience. Clinical translation will require mechanism‐linked potency assays, MISEV‐aligned EV reporting, biodistribution, GMP manufacturing,
Wenjing Lu, Junqiang Yan, Hongfang Feng
wiley   +1 more source