Results 181 to 190 of about 83,579 (259)

A feeder-free culture system supports long-term expansion and germline competence of bovine formative embryonic stem cells†. [PDF]

Biol Reprod
Chen L, Wang F, He J, Sun M, Wang Y, Wang Y, Wang S, An L, Xi G, Tian J.   +9 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, Volume 600, Issue 19, Page 2850-2873, October 2026.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

ERH elicits cell lineage restriction in mammalian preimplantation development and differentiation from pluripotency via H3K9me3-heterochromatin. [PDF]

Nat Commun
Katznelson A, Hernandez B, Tapia K, Fahning H, Burton A, Zhang J, Torres-Padilla ME, Plachta N, Zaret KS, McCarthy RL.   +9 more
europepmc   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, Volume 15, Issue 37, 9 October 2026.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Applied RNAi

Frontiers in Genetics, 2014
Bernard eMari, Barbara eBardoni
doaj   +1 more source

Understanding cancer as a systemic disease through comprehension of neural stemness as the core property of cancer cell and the basic rules it dictates. [PDF]

Front Cell Dev Biol
Cao Y.
europepmc   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, Volume 38, Issue 57, 13 October 2026.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Long-read RNA sequencing identifies non-coding isoform switching as a regulator of cell fate. [PDF]

Nat Commun
Fort V, Khelifi G, He R, Watters V, Pye M, Yamanaka N, Gertsenstein M, Lelong ÉIJ, Loehr J, Micha V, Lambert JP, Yamanaka Y, Wrana J, Hussein SMI.   +13 more
europepmc   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, Volume 13, Issue 56, 9 October 2026.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Signal-integrated control of immune and reparative programs establishes blood-derived fibrocytes reprogrammable toward induced pluripotency. [PDF]

Biol Open
Sylvester H, Koganti PP, Gurung S, Pillai VV, Selvaraj V.   +4 more
europepmc   +1 more source