Results 191 to 200 of about 62,870 (256)

Naïve human iPSCs obtained by culturing the ICGi022-A cell line with primed pluripotency in HENSM medium efficiently differentiate into endothelial derivatives. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Arssan MA, Shevchenko AI, Zakian SM, Zakharova IS.   +3 more
europepmc   +1 more source

Establishment of Human Formative Pluripotent Stem Cell‐Like Cells Exhibiting Amniotic Differentiation Potentials

Cell Proliferation, Volume 59, Issue 8, August 2026.
The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang, Qizhi Wang, Yu Wu, Chen Gu, Mingfei Li, Yong Fan, Xiangjin Kang, Lei Li, Zheng Gao, Mingyan Hei, Jianqiao Liu, Lei Li   +11 more
wiley   +1 more source

Enhancing reprogramming towards induced human expanded pluripotency through substitution of SOX2 with engineered SOX17 transcription factors. [PDF]

Commun Biol
Hu H, Ho DHH, Yeung SW, Tan Y, Ho SY, Weng M, Ruan D, Jauch R.   +7 more
europepmc   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, Volume 59, Issue 8, August 2026.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

NSD1 governs H3K36me2-mediated DNA methylation and drives endo-mesodermal differentiation of human iPSCs. [PDF]

Clin Epigenetics
Hansknecht A, Mankarious M, Baranda MV, Torlak ED, Wagner W, Zeevaert K, Puri D.   +6 more
europepmc   +1 more source

Immunophenotypic assessment of pure embryonal carcinoma and yolk sac tumour suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche

Histopathology, Volume 89, Issue 2, Page 303-311, August 2026.
Immunohistochemical analysis of transcription factors in GCNIS associated with pure EC and YST suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche. In these tumors, reprogramming may occur immediately upon invasion of the stroma or within seminiferous tubules but outside the spermatogonial niche (i.e., in intratubular ...
Daisy Maharjan, Květoslava Michalová, Joao Lobo, Jennifer Gordetsky, Fiona MacLean, Ankur R Sangoi, Daniel Berney, Chia‐Sui Kao, Costantino Ricci, Adeboye O Osunkoya, Maria Rosaria Raspollini, Geert JLH van Leenders, Muhammad T Idrees, Lee Ann Baldridge, Thomas M Ulbright, Andres M Acosta   +15 more
wiley   +1 more source

Stem cell research and regenerative medicine: meeting report from the Royan International Stem Cell Congress 2025. [PDF]

J Biol Eng
Bajool N, Abdolazimi M, Razzaznian M, Zakerian Z, Moradi S.   +4 more
europepmc   +1 more source

EMF2 deficiency disrupts epigenetic and chromatin organization landscapes, blocking root regeneration competence in Arabidopsis

New Phytologist, Volume 251, Issue 4, Page 1792-1810, August 2026.
EMF2 mutation alters transcriptomic profiles in Arabidopsis calli while retaining responsiveness during root induction. Summary Plant de novo organogenesis depends on callus formation, yet the epigenetic mechanisms governing organ regeneration remain poorly understood.
Zhidan Wang, May Avraham, Tali Mandel, Leor Eshed Williams, Chang Liu   +4 more
wiley   +1 more source

Strategies for the Selection and Application of Biological Scaffolds in Organ‐on‐a‐Chip Systems

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Organ‐on‐a‐chip (OoC) serves as a promising microphysiological platform for drug screening, disease modeling, and toxicity assessment. Biomimetic scaffolds are core components that determine the performance of OoC systems by mimicking the in vivo extracellular microenvironment.
Yichi Zhang, Ning Zhang, Linkai Jiang, Zhilong Zhou, Yuwei Zhang, Yuwen Wang, Yiting Lei, Ning Hu, Zhong Alan Li   +8 more
wiley   +1 more source

Revisiting viral reprogramming: Measles virus as a robust platform for high-quality iPSC generation. [PDF]

Mol Ther Adv
Moutaoufik MT, Chahine M.
europepmc   +1 more source