Results 201 to 210 of about 30,090 (224)

PML and PML nuclear bodies: Implications in antiviral defence

Biochimie, 2007
The establishment of an intracellular antiviral state is the defining activity of interferons (IFNs) as well as the property that permitted their discovery. Several pathways have been implicated in resistance to viral infection in IFN-treated cells, one of which implicates the ProMyelocytic Leukaemia (PML) protein and PML nuclear bodies (NBs, also ...
Everett, Roger, Chelbi-Alix, Mounira
openaire   +3 more sources

Performance of regular PML, CFS-PML, and second-order PML for waveguide problems

Microwave and Optical Technology Letters, 2006
The performance of regular, complex frequency shifted (CFS), and second-order perfectly matched layers (PMLs) is studied for the numerical simulation of waveguide problems. The limitations of each PML is clearly demonstrated. It is shown that the second-order PML is overall the best choice for a general problem, since the regular PML is incapable of ...
Davi Correia, Jian-Ming Jin
openaire   +1 more source

Opposing effects of PML and PML/RARα on STAT3 activity

Blood, 2003
Promyelocytic leukemia protein PML acts as a tumor suppressor, whereas its chimeric mutant promyelocytic leukemia/retinoic acid receptorα (PML/RARα) causes acute promyelocytic leukemia (APL). Because PML has been shown to form transcription-regulatory complexes with various molecules, we speculated that PML and/or PML/RARα might affect signal ...
Akira, Kawasaki, Itaru, Matsumura, Yoshihisa, Kataoka, Eri, Takigawa, Koichi, Nakajima, Yuzuru, Kanakura   +5 more
openaire   +2 more sources

A Cylindrical MRTD Algorithm With PML and Quasi-PML

IEEE Transactions on Microwave Theory and Techniques, 2013
In this paper, we develop an explicit multiresolution time-domain (MRTD) scheme based on Daubechies' scaling functions with a cylindrical grid for time-domain Maxwell's equations. The stability and dispersion property of the scheme is investigated and it is shown that larger cells decrease the numerical phase error, which makes it significantly lower ...
Yawen Liu, Yiwang Chen, Bin Chen, Xin Xu
openaire   +1 more source

PML-RARα and Its Phosphorylation Regulate PML Oligomerization and HIPK2 Stability

Cancer Research, 2013
Abstract The PML gene is frequently fused to the retinoic acid receptor α (RARα) gene in acute promyelocytic leukemia (APL), generating a characteristic PML-RARα oncogenic chimera. PML-RARα disrupts the discrete nuclear speckles termed nuclear bodies, which are formed in PML, suggesting that nuclear body disruption is involved in ...
Yutaka, Shima, Yuki, Honma, Issay, Kitabayashi   +2 more
openaire   +2 more sources

PML vaccines

Veterinary Record, 1987
  +7 more sources

Controlling senescence by PML and PML nuclear bodies

2017
Cellular senescence is a stress response wherein proliferating competent cells undergo a stable cell cycle arrest in response to a variety of intrinsic and extrinsic stimuli, including telomere shortening, oxidative stress, DNA damage or the constitutive activation of oncogenes among others. All these stimuli have in common the potential to initiate or
openaire   +1 more source

Progressive multifocal leukoencephalopathy (PML)

2013
Clinical History: A 50-year-old HIV positive male patient presented with deterioration of consciousness preceded by attacks of seizures and behavioural changes over a period of 2 weeks. His blood picture showed leukopaenia with neutrophil count < 400 cells/µL (Normal &... Final Diagnosis: Progressive multifocal leukoencephalopathy (PML)
openaire   +1 more source

Modal PML

IEEE Microwave and Guided Wave Letters, 1997
M. Okoniewski, M.A. Stuchly, M. Mrozowski, J. DeMoerloose   +3 more
openaire   +1 more source

PML

2008
openaire   +2 more sources