Results 51 to 60 of about 30,090 (224)

Atmospheric Correction Performance of Hyperspectral Airborne Imagery over a Small Eutrophic Lake under Changing Cloud Cover

open access: yesRemote Sensing, 2016
Atmospheric correction of remotely sensed imagery of inland water bodies is essential to interpret water-leaving radiance signals and for the accurate retrieval of water quality variables.
Lauri Markelin   +6 more
doaj   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang   +13 more
wiley   +1 more source

Effect of Milling Time and the Consolidation Process on the Properties of Al Matrix Composites Reinforced with Fe-Based Glassy Particles

open access: yesMetals, 2015
Al matrix composites reinforced with 40 vol% Fe50.1Co35.1Nb7.7B4.3Si2.8 glassy particles have been produced by powder metallurgy, and their microstructure and mechanical properties have been investigated in detail.
Özge Balcı   +7 more
doaj   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Promyelocytic leukemia (PML) protein plays important roles in regulating cell adhesion, morphology, proliferation and migration.

open access: yesPLoS ONE, 2013
PML protein plays important roles in regulating cellular homeostasis. It forms PML nuclear bodies (PML-NBs) that act like nuclear relay stations and participate in many cellular functions.
Mei Kuen Tang   +11 more
doaj   +1 more source

PML-II regulates ERK and AKT signal activation and IFNα-induced cell death

open access: yesCell Communication and Signaling, 2021
Background The requirement of promyelocytic leukaemia protein (PML) in interferon (IFN)-induced cell apoptosis is well-established. However, the exact mechanisms by which the multiple isoforms of PML protein participate in this process remain not well ...
Xueqiong Meng   +3 more
doaj   +1 more source

A Collaborative Approach to Addressing PML: The PML Consortium [PDF]

open access: yesJournal of Multiple Sclerosis, 2013
Progressive multifocal leukoencephalopathy (PML) is a rare but severe and often fatal disease of the central nervous system most commonly associated with severe immunodeficiency. PML occurs in many clinical conditions as shown in the table below (Table 1) [1-23]. The greatest number of PML cases occurs as a sequel to HIV infection.
William O. Iverson   +2 more
openaire   +1 more source

Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis

open access: yesAdvanced Materials, EarlyView.
Eutectozymes are sustainable hybrid materials that embed a GOx–HRP cascade within hydrophobic eutectogels featuring a dual supramolecular–covalent network. This architecture preserves native enzyme structure and stability, enables efficient heterogeneous biocatalysis in aqueous media, and positions eutectogels as robust platforms for next‐generation ...
Manuel Eduardo Martinez Cartagena   +10 more
wiley   +1 more source

The 10–23 DNAzyme in Biosensing and Diagnostics: Applications, Challenges, and Future Directions

open access: yesAngewandte Chemie, EarlyView.
This review focuses on the 10–23 DNAzyme in diagnostics, spanning unregulated and regulated target‐recognition modes, and their functionalization across colorimetric, fluorescent, electrochemical, electrochemiluminescent, and intracellular biosensing strategies.
Connor Nurmi   +5 more
wiley   +2 more sources

PML: Regulation and multifaceted function beyond tumor suppression

open access: yesCell & Bioscience, 2018
Promyelocytic leukemia protein (PML) was originally identified as a fusion partner of retinoic acid receptor alpha in acute promyelocytic leukemia patients with the (15;17) chromosomal translocation, giving rise to PML–RARα and RARα–PML fusion proteins ...
Kuo-Sheng Hsu, Hung-Ying Kao
doaj   +1 more source

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