Results 11 to 20 of about 6,165 (196)
Requirement of podocalyxin in TGF-beta induced epithelial mesenchymal transition. [PDF]
PLoS ONE, 2011 Epithelial mesenchymal transition (EMT) is characterized by the development of mesenchymal properties such as a fibroblast-like morphology with altered cytoskeletal organization and enhanced migratory potential.
Xiaobo Meng +2 more
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Podocalyxin and kidney diseases [PDF]
The Ukrainian Biochemical JournalSelectivity of blood filtration by the renal glomerulus is largely determined by the presence in its visceral epithelium of the terminally differentiated “octopus-like” cells called podocytes.
I. Kostovska
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Value of immunohistochemical expression of podocalyxin in active lupus nephritis
Nefrología (English Edition), 2018 Podocalyxin is an electronegative sialoglycoprotein that prevents the podocyte foot process from collapsing. The aim of this study was to detect an association between the glomerular immunohistochemical (IHC) expression of podocalyxin and the degree of ...
Maha Abdelmoneim Behairy +3 more
doaj +7 more sources
Role of urinary podocalyxin in early diagnosis of diabetic nephropathy [PDF]
Romanian Journal of Internal Medicine, 2020 Introduction. Podocyte injury has been reported as an early feature of DN therefore, the assessment of podocyte injury can be accomplished by estimation of podocalyxin in urine. This study aimed to estimate the urinary podocalyxin levels and to determine
Kostovska Irena +7 more
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Podocalyxin as a Prognostic Marker in Gastric Cancer.
PLoS ONE, 2015 BackgroundPodocalyxin-like 1 (PODXL) is a cell-adhesion glycoprotein associated with aggressive tumor phenotype and poor prognosis in several forms of cancer.
Alli Laitinen +6 more
doaj +4 more sources
Prediction of Possible Adverse Effects of Gestational Diabetes Mellitus on Maternal and Fetal Glomeruli by Urine and Amniotic Fluid Podocyte Degradation Products [PDF]
DiagnosticsObjectives: To compare the levels of podocyte damage markers nephrin and podocalyxin in urine samples taken at the time of gestational diabetes mellitus (GDM) diagnosis and at birth.
Fatma Tanilir Cagiran +3 more
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Assessment of urinary podocalyxin as a biomarker of early diagnosis of hypertensive nephropathy [PDF]
The Ukrainian Biochemical Journal, 2023 Chronically high blood pressure-related kidney injury is known as hypertensive nephropathy (HN). Podocyte damage in the pathogenesis of this disease can result in the release of the sialoglycoprotein podocalyxin into the urine, so podocalyxin may be ...
I. Kostovska +5 more
doaj +1 more source
Podocalyxin in Normal Tissue and Epithelial Cancer [PDF]
Cancers, 2021 Podocalyxin (PODXL), a glycosylated cell surface sialomucin of the CD34 family, is normally expressed in kidney podocytes, vascular endothelial cells, hematopoietic progenitors, mesothelium, as well as a subset of neurons. In the kidney, PODXL functions primarily as an antiadhesive molecule in podocyte epithelial cells, regulating adhesion and cell ...
Ngoc Le Tran, Yao Wang, Guiying Nie
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Scientific Reports, 2021 Podocalyxin overexpression associates with poor survival in pancreatic cancer (PDAC). We investigated whether podocalyxin expression correlates with treatment response or survival in neoadjuvant-treated PDAC.
Annika Eurola +6 more
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Podocalyxin in human haematopoietic cells [PDF]
British Journal of Haematology, 2004 SummaryPodocalyxin‐like protein (PCLP) is a sialomucin‐type membrane protein structurally related to CD34 and endoglycan. It was first described in glomerular podocytes and endothelial cells. In mice, PCLP is present in haemangioblasts, and in both chicken and mice it is a marker of early haematopoietic stem cells and lineage‐restricted haematopoietic ...
Laura, Kerosuo +5 more
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