Results 11 to 20 of about 6,232 (197)
Requirement of podocalyxin in TGF-beta induced epithelial mesenchymal transition. [PDF]
PLoS ONE, 2011 Epithelial mesenchymal transition (EMT) is characterized by the development of mesenchymal properties such as a fibroblast-like morphology with altered cytoskeletal organization and enhanced migratory potential.
Xiaobo Meng +2 more
doaj +3 more sources
Podocalyxin and kidney diseases [PDF]
The Ukrainian Biochemical JournalSelectivity of blood filtration by the renal glomerulus is largely determined by the presence in its visceral epithelium of the terminally differentiated “octopus-like” cells called podocytes.
I. Kostovska
doaj +2 more sources
Value of immunohistochemical expression of podocalyxin in active lupus nephritis
Nefrología (English Edition), 2018 Podocalyxin is an electronegative sialoglycoprotein that prevents the podocyte foot process from collapsing. The aim of this study was to detect an association between the glomerular immunohistochemical (IHC) expression of podocalyxin and the degree of ...
Maha Abdelmoneim Behairy +3 more
doaj +7 more sources
Role of urinary podocalyxin in early diagnosis of diabetic nephropathy [PDF]
Romanian Journal of Internal Medicine, 2020 Introduction. Podocyte injury has been reported as an early feature of DN therefore, the assessment of podocyte injury can be accomplished by estimation of podocalyxin in urine. This study aimed to estimate the urinary podocalyxin levels and to determine
Kostovska Irena +7 more
doaj +3 more sources
Podocalyxin as a Prognostic Marker in Gastric Cancer.
PLoS ONE, 2015 BackgroundPodocalyxin-like 1 (PODXL) is a cell-adhesion glycoprotein associated with aggressive tumor phenotype and poor prognosis in several forms of cancer.
Alli Laitinen +6 more
doaj +4 more sources
Podocalyxin in Normal Tissue and Epithelial Cancer [PDF]
Cancers, 2021 Podocalyxin (PODXL), a glycosylated cell surface sialomucin of the CD34 family, is normally expressed in kidney podocytes, vascular endothelial cells, hematopoietic progenitors, mesothelium, as well as a subset of neurons. In the kidney, PODXL functions primarily as an antiadhesive molecule in podocyte epithelial cells, regulating adhesion and cell ...
Ngoc Le Tran, Yao Wang, Guiying Nie
openaire +2 more sources
Scientific Reports, 2021 Podocalyxin overexpression associates with poor survival in pancreatic cancer (PDAC). We investigated whether podocalyxin expression correlates with treatment response or survival in neoadjuvant-treated PDAC.
Annika Eurola +6 more
doaj +1 more source
Podocalyxin in human haematopoietic cells [PDF]
British Journal of Haematology, 2004 SummaryPodocalyxin‐like protein (PCLP) is a sialomucin‐type membrane protein structurally related to CD34 and endoglycan. It was first described in glomerular podocytes and endothelial cells. In mice, PCLP is present in haemangioblasts, and in both chicken and mice it is a marker of early haematopoietic stem cells and lineage‐restricted haematopoietic ...
Laura, Kerosuo +5 more
openaire +2 more sources
Podocalyxin : A Marker of Blasts in Acute Leukemia [PDF]
American Journal of Clinical Pathology, 2005 Podocalyxin is a CD34 family member expressed by podocytes, vascular endothelium, mesothelium, and a subset of hematopoietic progenitors. Podocalyxin expression was not observed in the hematopoietic cells of normal adult bone marrow samples. However, podocalyxin was expressed by blasts in 30 (77%) of 39 cases of acute myeloid leukemia (AML), 22 (81 ...
Todd W, Kelley +4 more
openaire +2 more sources
Levels of serum podocalyxin in preeclampsia and relationship with maternal echocardiographic and doppler ultrasound parameters [PDF]
Folia Medica, 2022 Introduction: Podocalyxin (PCX) is an indicator of glomerular injury. Aside from the kidney, it is expressed in the endothelial cells of various organs.
Asparuh G. Nikolov +2 more
doaj +3 more sources