Results 31 to 40 of about 3,511 (163)

Relationship between Elevated Maternal Serum Podocalyxin Concentrations with Blood Pressure Values and Routine Laboratory Parameters in Preeclampsia [PDF]

Journal of Biomedical & Clinical Research, 2021
Podocalyxin (PCX) is a glycoprotein member of the CD34 transmembrane sialomucin family and covers the surface of podocytes. It is assumed to be a marker of glomerular endothelial injury. In conditions, podocalyxin excretion in the urine is increased as a
Nikola Popovski, Asparuh Nikolov, Yordan Popov, Svetla Blazheva   +3 more
doaj   +3 more sources

A tumor-restricted glycoform of podocalyxin is a highly selective marker of immunologically cold high-grade serous ovarian carcinoma

Frontiers in Oncology, 2023
IntroductionTargeted-immunotherapies such as antibody-drug conjugates (ADC), chimeric antigen receptor (CAR) T cells or bispecific T-cell engagers (eg, BiTE®) all aim to improve cancer treatment by directly targeting cancer cells while sparing healthy ...
Julyanne Brassard, Michael R. Hughes, Pamela Dean, Diana Canals Hernaez, Shelby Thornton, Allyson C. Banville, Julian Smazynski, Mary Warren, Kevin Zhang, Katy Milne, C. Blake Gilks, Anne-Marie Mes-Masson, David G. Huntsman, David G. Huntsman, Brad H. Nelson, Calvin D. Roskelley, Kelly M. McNagny   +16 more
doaj   +1 more source

Urinary and Kidney Podocalyxin and Podocin Levels in Diabetic Kidney Disease: A Kidney Biopsy StudyPlain-Language Summary

Kidney Medicine, 2023
Rationale & Objective: Diabetic kidney diseases (DKDs) are the most common cause of dialysis-dependent kidney disease around the world. Previous studies have suggested that urinary level of podocyte-associated molecules may predict the prognosis of ...
Lingfeng Zeng, Winston Wing-Shing Fung, Gordon Chun-Kau Chan, Jack Kit-Chung Ng, Kai-Ming Chow, Cheuk-Chun Szeto   +5 more
doaj   +1 more source

Release of podocalyxin into the extracellular space. Role of metalloproteinases.

Biochimica et biophysica acta, 2011
Peer ...
Fernández, Darío, Larrucea, Susana, Nowakowski, Adam, Pericacho, Miguel, Parrilla, Roberto L., Sánchez Ayuso, Matilde   +5 more
openaire   +4 more sources

Serum podocalyxin levels in patients with obesity and carbohydrates disorders [PDF]

Pharmacia
Background: Podocalyxin is expressed not only in glomerular podocytes but also on the endothelial cell surface outside the kidney. The aim of this cross-sectional study is to evaluate the role of serum podocalyxin as an early marker for vascular injury ...
Iveta Nedeva, Vera Karamfilova, Vlayko Vodenicharov, Antonina Gerganova, Tsvetelina Velikova, Yavor Assyov   +5 more
doaj   +3 more sources

SGLT2抑制剂对糖尿病肾病患者的影响:基于尿足细胞的初步研究

Journal of Diabetes, 2022
Background The aim of this study was to investigate the effects of sodium glucose cotransporter 2 inhibitors (SGLT2i) on the glomerulus through the evaluation of podocyturia in patients with diabetic kidney disease (DKD). Methods The study population was
Emre Durcan, Serbay Ozkan, Halil Ibrahim Saygi, Mevlut Tamer Dincer, Ozge Polat Korkmaz, Serdar Sahin, Cebrail Karaca, Cem Sulu, Alev Bakir, Hande Mefkure Ozkaya, Sinan Trabulus, Elif Guzel, Nurhan Seyahi, Mustafa Sait Gonen   +13 more
doaj   +1 more source

Glycan Epitopes on 201B7 Human-Induced Pluripotent Stem Cells Using R-10G and R-17F Marker Antibodies

Biomolecules, 2021
We developed two human-induced pluripotent stem cell (hiPSC)/human embryonic stem cell (hESC)-specific glycan-recognizing mouse antibodies, R-10G and R-17F, using the Tic (JCRB1331) hiPSC line as an antigen. R-10G recognizes a low-sulfate keratan sulfate,
Yuko Nagai, Hiromi Nakao, Aya Kojima, Yuka Komatsubara, Yuki Ohta, Nana Kawasaki, Nobuko Kawasaki, Hidenao Toyoda, Toshisuke Kawasaki   +8 more
doaj   +1 more source

Urinary Nephrin and Podocalyxin Levels as Predictors of Pre-eclampsia in High-Risk Pregnant Women [PDF]

Folia Medica, 2021
Introduction: Pre-eclampsia (PE) is characterized by new-onset hypertension and proteinuria. Damage of podocyte cells has been reported in pre-eclamptic women, thus podocyte specific proteins such as nephrin and podocalyxin could be useful biomarkers in ...
Irena Kostovska, Katerina Tosheska Trajkovska, Ognen Kostovski, Danica Labudovic   +3 more
doaj   +3 more sources

Podocalyxin is a marker of poor prognosis in colorectal cancer [PDF]

BMC Cancer, 2014
Over two decades ago, a proposal was that two different colorectal cancer (CRC) entities existed, based on tumour location either proximal (right) or distal (left) of the splenic flexure. Proximal and distal tumours exhibit different clinical, epidemiological, and biological characteristics.
Haglund Caj, Boeckelman Camilla, Mustonen Harri, Hagstroem Jaana, Böckelman Camilla, Haglund Caj, Boeckelman Camilla, Mustonen Harri, Hagstroem Jaana   +8 more
openaire   +4 more sources

Podocalyxin as a Prognostic Marker in Gastric Cancer

PLOS ONE, 2015
Podocalyxin-like 1 (PODXL) is a cell-adhesion glycoprotein associated with aggressive tumor phenotype and poor prognosis in several forms of cancer. The aim of this study was to investigate PODXL expression in gastric cancer by use of two different antibodies.By tumor-tissue microarrays and immunohistochemistry we evaluated PODXL expression in tumor ...
Laitinen, Alli, Bockelman, Camilla, Hagstrom, Jaana, Kokkola, Arto, Fermer, Christian, Nilsson, Olle, Haglund, Caj   +6 more
openaire   +5 more sources