Results 51 to 60 of about 6,165 (196)

Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion [PDF]

open access: yes, 2012
Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum. Here, we show that
Hodgson, Lorna   +3 more
core   +2 more sources

Evaluation of human umbilical cord blood as a source of embryonic stem cells [PDF]

open access: yes, 2013
Human umbilical cord blood (HUCB) has been poorly characterised as a source of embryonic stem cells (ESCs). The aim of this study, therefore, was to evaluate HUCB as source of mesenchymal stem cells (MSCs) with embryonic characteristics.
El-Sheemy, Mohamed   +3 more
core   +2 more sources

The CD34-related molecule podocalyxin is a potent inducer of microvillus formation.

open access: yesPLoS ONE, 2007
BackgroundPodocalyxin is a CD34-related transmembrane protein involved in hematopoietic cell homing, kidney morphogenesis, breast cancer progression, and epithelial cell polarization.
Julie S Nielsen   +5 more
doaj   +1 more source

Atypical focal segmental glomerulosclerosis associated with a new PODXL nonsense variant

open access: yesMolecular Genetics & Genomic Medicine, 2021
Background Podocalyxin (PODXL) is a highly sialylated adhesion glycoprotein that plays an important role in podocyte's physiology. Recently, missense and nonsense dominant variants in the PODXL gene have been associated with focal segmental ...
David Marx   +10 more
doaj   +1 more source

Podocalyxin enhances the adherence of cells to platelets

open access: yesCellular and Molecular Life Sciences, 2007
Podocalyxin (PODXL) is a mucin protein of the CD34 family expressed in kidney glomerular podocytes, vascular endothelium, progenitor bone marrow and tumor cells. It is assumed that PODXL plays an anti-adherent role in kidney podocytes. CHO cells stably expressing human PODXL (CHO-PODXL) or human tumor cells (Tera-1) inherently expressing PODXL showed ...
Larrucea, Susana   +6 more
openaire   +3 more sources

Markers of kidney injury, lipid metabolism, and carbonyl stress in patients with type 1 diabetes and different levels of albuminuria

open access: yesБюллетень сибирской медицины, 2022
The aim of this work was to study the levels of podocalyxin and β-2-microglobulin and parameters of lipid metabolism and carbonyl stress in type 1 diabetes mellitus (T1DM) patients with different levels of albuminuria.Materials and methods.
M. A. Darenskaya   +6 more
doaj   +1 more source

Editorial overview: Membrane traffic and cell polarity [PDF]

open access: yes, 2016
No abstract ...
Bryant, David M., Yap, Alpha S.
core   +1 more source

Long term follow up of biomarkers of podocyte damage and renal function in patients with and without preeclampsia

open access: yesBrazilian Journal of Nephrology, 2018
Introduction: preeclampsia can be associated with future renal disease. Objectives: To measure changes in renal function overtime in patients with preeclampsia.
Ylbe Palacios de Franco   +6 more
doaj   +1 more source

Environmental factors and risk of aggressive prostate cancer among a population of New Zealand men - a genotypic approach [PDF]

open access: yes, 2017
Prostate cancer is one of the most significant health concerns for men worldwide. Numerous researchers carrying out molecular diagnostics have indicated that genetic interactions with biological and behavioral factors play an important role in the ...
Bishop, Karen S.   +15 more
core   +2 more sources

Urinary Podocalyxin as a Biomarker to Diagnose Membranous Nephropathy

open access: yesPLOS ONE, 2016
A non-invasive diagnostic marker of membranous nephropathy (MN) is desirable. The urinary level of podocalyxin (PCX) is higher in various glomerular diseases, including MN. The aim of this study was to construct a diagnostic model of MN with the combination of urinary PCX and clinical parameters.We performed this cross-sectional study to construct the ...
Takahiro Imaizumi   +9 more
openaire   +4 more sources

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