Results 111 to 120 of about 7,139 (201)
Effects of Quinazolinones on the Development of BALB/c Mice [PDF]
, 2009 Objective(s)Quinazolinones are heterocyclic components (able to form cyclized compounds) which have several medical effects such as anti-malarial, spasmolytic, anti-microbial, sedative, etc.
Daryush Minaei Tehrani +3 more
core
Full-length soluble urokinase plasminogen activator receptor down-modulates nephrin expression in podocytes [PDF]
, 2015 Increased plasma level of soluble urokinase-type plasminogen activator receptor (suPAR) was associated recently with focal segmental glomerulosclerosis (FSGS).
Alfano, Massimo +14 more
core +2 more sources
Active focal segmental glomerulosclerosis is associated with massive oxidation of plasma albumin [PDF]
, 2007 The basic mechanism for idiopathic FSGS still is obscure. Indirect evidence in humans and generation of FSGS by oxidants in experimental models suggest a role of free radicals.
BRUSCHI M +12 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2012 目的检测肥胖患者肾小球足细胞上Podocin的蛋白分布和表达,探讨Podocin在肥胖导致蛋白尿中的变化及意义。方法收集肾脏切除病理标本,取其相对正常肾脏皮质,体重指数(BMI)≥28kg/m2者16例作为肥胖组(Ob组 ...
杜娟 +5 more
doaj
Intravital imaging reveals angiotensin II–induced transcytosis of albumin by podocytes [PDF]
, 2015 Albuminuria is a hallmark of kidney disease of various etiologies and usually caused by deterioration of glomerular filtration barrier integrity. We recently showed that angiotensin II (Ang II) acutely increases albumin filtration in the healthy kidney.
Castrop, Hayo +6 more
core +1 more source
Autophagy in patients with lupus nephritis and its effect on podocyte related protein expression
Linchuang shenzangbing zazhi, 2020 Objective To investigate the autophagy in patients with lupus nephritis(LN)and its effect on podocyte related protein expression.Methods A total of 69 LN patients(LN group),including 50 cases of systemic lupus erythematosus(SLE group)and 50 patients with
LI Zhang-hong, ZHANG Rui-rui, LUO Qiu-ju
doaj
BMC Complementary and Alternative Medicine, 2019 Background Wenshen Jianpi recipe (WSJPR), a blended traditional Chinese medicine, is considered to have the possible beneficial effect on the progression of diabetic nephropathy (DN).
Xiaodan Cao +6 more
doaj +1 more source
Immunofluorescence laser micro-dissection of specific nephron segments in the mouse kidney allows targeted downstream proteomic analysis [PDF]
, 2015 Laser micro-dissection (LMD) is a very useful tool that allows the isolation of finite areas from tissue specimens for downstream analysis of RNA and protein.
El-Achkar, Tarek M. +2 more
core +1 more source
Mechanisms by which heme oxygenase rescue renal dysfunction in obesity
Redox Biology, 2014 Obesity and excessive inflammation/oxidative stress are pathophysiological forces associated with kidney dysfunction. Although we recently showed that heme-oxygenase (HO) improves renal functions, the mechanisms are largely unclear. Moreover, the effects
Joseph Fomusi Ndisang, Shuchita Tiwari
doaj +1 more source
Canadian Journal of Kidney Health and DiseaseBackground: Diabetic kidney disease (DKD) is the most common and deranging microvascular complication of diabetes mellitus (DM). Podocytopathy is a key component of glomerular damage in DKD. Micro RNA-21 (miRNA-21) is an epigenetic regulator that plays a
Pringgodigdo Nugroho +9 more
doaj +1 more source