Results 111 to 120 of about 7,104 (202)

Activation of podocyte Notch mediates early Wt1 glomerulopathy [PDF]

, 2018
The Wilms' tumor suppressor gene, WT1, encodes a zinc finger protein that regulates podocyte development and is highly expressed in mature podocytes. Mutations in the WT1 gene are associated with the development of renal failure due to the formation of ...
Alex K. Virasami, Aoife M. Waters, Barbaux, Barua, Bharathavikru, Boyer, Bruckner, Bruening, Cassady, Chau, Chen, Cheng, Cheng, Chernin, Chung, Dale Moulding, Denamur, Denys, Eve V. Miller-Hodges, Hartwig, Hastie, Hayashi, Jack Bellerby, Johns, Kakuda, Kann, Klamt, Krebs, Lefebvre, Lipska, Liu, Livak, Mona M. Tahoun, Morimoto, Murea, Neil J. Sebire, Niranjan, O'Brien, Okajima, Patek, Pelletier, Pelletier, Peter Hohenstein, Peter J. Scambler, Piscione, Rheault, Robert D. Sampson, Rowan I. Asfahani, Saran, Schiffer, Shigehara, Sweetwyne, Taelman, Toska, Totaro, Waters, Waters, White, Yang   +58 more
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自然発症高血圧ラットにおける七物降下湯の腎保護作用 [PDF]

, 2015
富山大学・富医薬博甲第177号・馬躍・2015/09/28・★論文非公開 ...
馬 躍
core   +1 more source

Full-length soluble urokinase plasminogen activator receptor down-modulates nephrin expression in podocytes [PDF]

, 2015
Increased plasma level of soluble urokinase-type plasminogen activator receptor (suPAR) was associated recently with focal segmental glomerulosclerosis (FSGS).
Alfano, Massimo, Cinque, Paola, Giusti, Guido, Proietti, Silvia, Nebuloni, Manuela, Danese, Silvio, D'Alessio, Silvia, Genua, Marco, Portale, Federica, Lo Porto, Manuela, Singhal, Pravin C, Rastaldi, Maria Pia, Saleem, Moin A, Mavilio, Domenico, Mikulak, Joanna   +14 more
core   +2 more sources

Immunofluorescence laser micro-dissection of specific nephron segments in the mouse kidney allows targeted downstream proteomic analysis [PDF]

, 2015
Laser micro-dissection (LMD) is a very useful tool that allows the isolation of finite areas from tissue specimens for downstream analysis of RNA and protein.
El-Achkar, Tarek M., Khan, Shehnaz, Micanovic, Radmila   +2 more
core   +1 more source

Autophagy in patients with lupus nephritis and its effect on podocyte related protein expression

Linchuang shenzangbing zazhi, 2020
Objective To investigate the autophagy in patients with lupus nephritis(LN)and its effect on podocyte related protein expression.Methods A total of 69 LN patients(LN group),including 50 cases of systemic lupus erythematosus(SLE group)and 50 patients with
LI Zhang-hong, ZHANG Rui-rui, LUO Qiu-ju
doaj  

Renal tubular Sirt1 attenuates diabetic albuminuria by epigenetically suppressing Claudin-1 overexpression in podocytes [PDF]

, 2013
Sirtuin 1 (Sirt1), a NAD[superscript +]-regulated deacetylase with numerous known positive effects on cellular and whole-body metabolism, is expressed in the renal cortex and medulla.
A Leelahavanichkul, A Purushotham, A Zorzano, AC Huby, B Clodfelder-Miller, C Dai, CD Cohen, DM Gibb, Eiji Kubota, F Fuks, H Rincon-Choles, Hirobumi Tokuyama, Hiroshi Itoh, Hitoshi Minakuchi, HM O'Hagan, HM Taha, J Turek-Plewa, J Zhang, JT Rodgers, JV Bonventre, K Asanuma, K Hasegawa, K Hasegawa, K Terasawa, K Tikoo, KA Moynihan, Kazuhiro Hasegawa, Keiko Fujimura, KM Ramsey, Koichi Hayashi, Kozi Hosoya, L Bordone, L Formentini, L Peng, L Peng, Leonard Guarente, LW Lai, M Kitada, M Kitada, M Orimo, MJ Moeller, Motoaki Komatsu, P Dhawan, P Wang, P Wang, PD Leotlela, Petra Simic, Q Zhang, RE Gilbert, RH Wang, S Boireau, S Kume, SA Roxburgh, SH Sung, Shu Wakino, T Nedachi, T Ohse, T Ohse, Takeshi Kanda, VS Vaidya, W He, Y Kohda, Y Nakahata, Y Xu, Y Zhang, Yuka Kaneko, Yusuke Sakamaki, Z Zhang   +67 more
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The Correlation of MicroRNA-21 With the Nephrin, Podocin, and Urinary Albumin-Creatinine Ratio in Patients With Type 2 Diabetes and Albuminuria: A Cross-Sectional Study

Canadian Journal of Kidney Health and Disease
Background: Diabetic kidney disease (DKD) is the most common and deranging microvascular complication of diabetes mellitus (DM). Podocytopathy is a key component of glomerular damage in DKD. Micro RNA-21 (miRNA-21) is an epigenetic regulator that plays a
Pringgodigdo Nugroho, Tri Hadi Susanto, Maruhum Bonar, Aulia Rizka, Aida Lydia, Soekamto Koesno, Pradana Soewondo, Hamzah Shatri, Carissa Cornelia Chundiawan, Fidel Hermanto   +9 more
doaj   +1 more source

厄贝沙坦对早期糖尿病肾脏疾病大鼠足细胞nephrin和podocin表达的影响

Linchuang shenzangbing zazhi, 2014
目的 观察厄贝沙坦（irbesartan）对糖尿病肾脏疾病（diabetic kidney disease,DKD）大鼠足细胞裂孔隔膜蛋白分子（nephrin和podocin）表达的影响,探讨厄贝沙坦对DKD的防治作用。方法 以高脂高糖喂养8周联合小剂量链脲佐菌素（30 rmg/kg）建立DKD大鼠模型,将DKD大鼠模型随机分为2组:厄贝沙坦组及模型对照组;另设正常对照组。厄贝沙坦组给予厄旦沙坦(50 mg·kg-1·d-1),另外2组每日给予等量0.9%生理盐水灌胃。各组于治疗前及药物干预后第4、8 ...
岳少姮
doaj  

Correlation of Asymmetric Dimethylarginine With Podocytopathy Markers in Diabetic Kidney Disease Patients

International Journal of Nephrology and Renovascular Disease
Pringgodigdo Nugroho,1 Riahdo Juliarman Saragih,2 Aida Lydia,1 Muhadi Muhadi,3 Harry Isbagio,4,5 Hamzah Shatri,6 Carissa Cornelia Chundiawan,1 Fidel Hermanto1 1Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine,
Nugroho P, Saragih RJ, Lydia A, Muhadi M, Isbagio H, Shatri H, Chundiawan CC, Hermanto F   +7 more
doaj  

Evaluation of urinary podocin and nephrin as markers of podocyturia in dogs with leishmaniosis

Parasites & Vectors
Background Renal disease is the main cause of death in canine leishmaniosis. Detection of an active glomerular injury is important to identify early renal damage and to prevent the development of chronic kidney disease.
Valeria Pantaleo, Tommaso Furlanello, Erika Carli, Laura Ventura, Laia Solano-Gallego   +4 more
doaj   +1 more source