Results 131 to 140 of about 39,389 (304)

Isolation of cDNA encoding full‐length rat (Rattus norvegicus) poly(ADP‐ribose) polymerase [PDF]

, 1997
Sascha Beneke, Ralph G. Meyer, Alexander Bürkle   +2 more
openalex   +1 more source

Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres

Molecular and Cellular Biology, 2002
Brandoch D. Cook, Jasmin N. Dynek, William G Chang, Grigoriy A Shostak, Susan Smith   +4 more
semanticscholar   +1 more source

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

UroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

The role of poly(ADP-ribose) polymerases in manganese exposed Caenorhabditis elegans. [PDF]

J Trace Elem Med Biol, 2020
Neumann C, Baesler J, Steffen G, Nicolai MM, Zubel T, Aschner M, Bürkle A, Mangerich A, Schwerdtle T, Bornhorst J.   +9 more
europepmc   +1 more source

CADD-13. COMBINED INHIBITION OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND POLY (ADP-RIBOSE) POLYMERASE (PARP) IMPAIRS GLIOBLASTOMA CELL GROWTH [PDF]

, 2018
Lee Hwang, Yu-Ting Su, Michael Vogelbaum, Mark R. Gilbert, Jing Wu   +4 more
openalex   +1 more source

Biology of Poly(ADP-Ribose) Polymerases: The Factotums of Cell Maintenance.

Molecules and Cells, 2015
P. Bai
semanticscholar   +1 more source

Development and Real‐World Evaluation of a Statewide Mainstream Model of Germline Genetic Testing for BRCA1/2 and Mismatch Repair Gene Variants (Lynch Syndrome)

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This translational quality improvement study evaluated a statewide pathway for mainstream genetic testing in South Australia. Adoption of mainstream BRCA1/2 testing increased significantly, but not MMR testing. Findings highlight the need for tailored, context‐specific strategies to integrate genetic testing into routine care across diverse cancer ...
Cally A. Jennings, Kathryn Cornthwaite, Michael Osborn, Ganessan Kichenadasse, Eryn Dow   +4 more
wiley   +1 more source

Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells [PDF]

, 2015
Ahrum Min, Seock‐Ah Im, Debora Keunyoung Kim, Sang-Hyun Song, Hee Jun Kim, Kyung-Hun Lee, Tae‐Yong Kim, Sae‐Won Han, Do‐Youn Oh, Tae‐You Kim, Mark J. O’Connor, Yung‐Jue Bang   +11 more
openalex   +1 more source

Data from Oral Poly(ADP-Ribose) Polymerase-1 Inhibitor BSI-401 Has Antitumor Activity and Synergizes with Oxaliplatin against Pancreatic Cancer, Preventing Acute Neurotoxicity

, 2023
Davide Melisi, Valeria Ossovskaya, Cihui Zhu, Roberta Rosa, Jianhua Ling, Patrick M. Dougherty, Barry M. Sherman, James L. Abbruzzese, Paul J. Chiao   +8 more
openalex   +1 more source

Selective small molecule targeting of KDM4 as a therapeutic strategy to reduce proliferation of acute myeloid leukaemia

British Journal of Haematology, EarlyView.
Summary Acute myeloid leukaemia (AML) is an aggressive disease with poor survival and high relapse rates. Coupled with the complex mutational burden observed, there is an unmet clinical need for more targeted therapies. Epigenetic therapies have shown promise both as monotherapy and in combination strategies and specifically histone lysine demethylase,
Laura Monaghan, Roderick P. Bunschoten, Joana Bittencourt‐Silvestre, Taeju Park, Susan Gannon, Petrisor Alin Pirvan, Alex Hoose, Helen Wheadon, Robert M. J. Liskamp, Xu Huang, Heather G. Jørgensen   +10 more
wiley   +1 more source