Results 91 to 100 of about 66,094 (222)

Ere, a Family of Short Interspersed Elements in the Genomes of Odd-Toed Ungulates (Perissodactyla)

Animals
Short Interspersed Elements (SINEs) are eukaryotic retrotransposons transcribed by RNA polymerase III (pol III). Many mammalian SINEs (T+ SINEs) contain a polyadenylation signal (AATAAA), a pol III transcription terminator, and an A-rich tail in their 3′-
Ilia G. Ustyantsev, Sergey A. Kosushkin, Olga R. Borodulina, Nikita S. Vassetzky, Dmitri A. Kramerov   +4 more
doaj   +1 more source

A tail of translational regulation

eLife, 2017
An RNA-binding protein called PABPC1 has an important role in determining protein synthesis rates and hypertrophy in the heart.
Gillian A Gray, Nicola K Gray
doaj   +1 more source

Full‐length transcriptome profiling of true bug mitochondrial genomes reveals the unique transcriptional regulation during insect evolution

Insect Science, EarlyView.
The mitogenome was transcribed into complete primary polycistrons on both strands. The heteropteran mitochondrial transcription termination factor (HmTTF) functions as a bidirectional attenuator rather than a terminator, and co‐evolution of HmTTF and the binding sites was observed.
Shiwen Xu, Yuange Duan, Ling Ma, Qiaoqiao Liu, Fan Song, Wanzhi Cai, Hu Li   +6 more
wiley   +1 more source

Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors

Frontiers in Cellular Neuroscience, 2019
Alternative polyadenylation (APA) is a widespread mechanism involving about half of the expressed genes, resulting in varying lengths of the 3′ untranslated region (3′UTR).
Elena Grassi, Roberto Santoro, Alessandro Umbach, Anna Grosso, Salvatore Oliviero, Salvatore Oliviero, Francesco Neri, Francesco Neri, Luciano Conti, Ugo Ala, Paolo Provero, Ferdinando DiCunto, Ferdinando DiCunto, Giorgio R. Merlo   +13 more
doaj   +1 more source

Activity-dependent polyadenylation in neurons

, 2009
Activity-dependent changes in protein synthesis modify synaptic efficacy. One mechanism that regulates mRNA translation in the synapto-dendritic compartment is cytoplasmic polyadenylation, a process controlled by CPEB, the cytoplasmic polyadenylation ...
Richter, Joel D., Du, Ling
core   +1 more source

Analysis of RNA Transcribed by RNA Polymerase III from B2 SINEs in Mouse Cells

Non-Coding RNA
Background/Objectives: SINEs (short interspersed elements) are eukaryotic non-autonomous retrotransposons. They are transcribed by RNA polymerase III (pol III) and generate non-coding RNAs.
Olga R. Borodulina, Sergey A. Kosushkin, Ilia G. Ustyantsev, Nikita S. Vassetzky, Dmitri A. Kramerov   +4 more
doaj   +1 more source

PABPC1 in Cancer: From a Translational Housekeeper to a Stress‐Responsive Regulatory Hub

Cancer Science, EarlyView.
PABPC1 shifts from a translational housekeeper to a stress‐responsive oncogenic hub via phase separation, PTMs, and non‐coding RNA crosstalk, selectively driving oncogene translation and therapy resistance in cancer. ABSTRACT PABPC1, long recognized as a constitutive translational housekeeper, has emerged as a stress‐responsive translational ...
Cuiwei Zhang, Ye Zhu, Wenbo Long
wiley   +1 more source

Aedes aegypti ferritin heavy chain homologue: feeding of iron or blood influences message levels, lengths and subunit abundance

Journal of Insect Science, 2002
Secreted ferritin in the mosquito, Aedes aegypti, has several subunits that are the products of at least two genes, one encoding a homologue of the vertebrate heavy chain (HCH) and the other the light chain homologue (LCH).
Boris C. Dunkov, Teodora Georgieva, Toyoshi Yoshiga, Martin Hall, John H. Law   +4 more
doaj  

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Position-dependent inhibition of the cleavage step of pre-mRNA 3'-end processing by U1 snRNP [PDF]

, 2000
The 3' ends of most eukaryotic pre-mRNAs are generated by 3' endonucleolytic cleavage and subsequent polyadenylation. 3'-end formation can be influenced positively or negatively by various factors.
Gunderson, S. I., Mattaj, I. W., Rüegsegger, U., Keller, W., Vagner, S.   +4 more
core