Results 91 to 100 of about 57,622 (148)

Copper Amine Oxidase (CuAO)-Mediated Polyamine Catabolism Plays Potential Roles in Sweet Cherry (Prunus avium L.) Fruit Development and Ripening. [PDF]

Int J Mol Sci, 2022
Cao X, Wen Z, Shang C, Cai X, Hou Q, Qiao G.   +5 more
europepmc   +1 more source

Mathematical modelling of polyamine metabolism in bloodstream-form trypanosoma brucei: An application to drug target identification [PDF]

, 2013
© 2013 Gu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Desmond J Higham, Xu Gu (276054), Gilbert, D, Gu, X, David Reid (276055), Desmond J. Higham (261142), Reid, D, David Gilbert, David Reid, Gilbert David, Gu Xu, David Gilbert (276056), Reid David, Desmond J. Higham, Xu Gu, Higham, DJ, Higham Desmond J.   +16 more
core   +2 more sources

Polyamines at the crossroad between cell metabolism and epigenetic regulation in acute leukemias

Cell Death Discovery
Polyamines, namely putrescine, spermidine and spermine, are involved in multiple molecular pathways through their ability to bind nucleic acids and modulate protein stability.
Francesca Pirini, Anna Ferrari, Mouna Jandoubi, Irene Azzali, Davide Angeli, Rossana Mondrone, Chiara Bracci, Francesca Ruggieri, Giovanni Martinelli, Giorgia Simonetti   +9 more
doaj   +1 more source

Subtype‐Specific Transcription Factors Affect Polyamine Metabolism and the Tumor Microenvironment in Breast Cancer

Cancer Innovation
Background Polyamines play important roles in cell growth and proliferation. Polyamine metabolism genes are dysregulated in various tumors. Some polyamine metabolism genes are regulated by transcription factors.
Qi Song, Yixuan Wang, Sen Liu
doaj   +1 more source

Functions of polyamine acetylation

, 1987
Acetylation is a means to decrease the net positive charge of the plyamines and thus liberate polyamines from anionic binding sites. The acetyl derivatives can be removed from the cells by transport and catabolism. Intracellular polyamine metabolism can
Nikolaus Seiler
core   +1 more source

Role of polyamine metabolism in plant pathogen interactions

, 2017
Polyamines are aliphatic amines found in all living cells, and they are necessary for several fundamental cell processes. Their protective role against various abiotic stress factors has been reported in different plant species, while the mechanism by ...
Magda Pal*, Tibor Janda, Pal M
core   +1 more source

Polyamine Drug Discovery: Synthetic Approaches to Therapeutic Modulators of Polyamine Metabolism

, 2011
Numerous synthetic compounds have been described that either act as inhibitors of enzymes involved in polyamine metabolism or otherwise modulate these pathways.
Patrick M. Woster
core   +1 more source

Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy. [PDF]

Nat Commun, 2020
Affronti HC, Rowsam AM, Pellerite AJ, Rosario SR, Long MD, Jacobi JJ, Bianchi-Smiraglia A, Boerlin CS, Gillard BM, Karasik E, Foster BA, Moser M, Wilton JH, Attwood K, Nikiforov MA, Azabdaftari G, Pili R, Phillips JG, Casero RA, Smiraglia DJ.   +19 more
europepmc   +1 more source

Polyamine-Induced Hormonal Changes in eds5 and sid2 Mutant Arabidopsis Plants

, 2019
Polyamines are multifaceted compounds which play a role in regulating plant growth and stress tolerance in interactions with plant hormones. The aim of the present study was to reveal how exogenous polyamines influence the synthesis of salicylic acid ...
Imre Majláth, Tibor Janda, Judit Tajti, Edit Németh, Kamirán Áron Hamow, Krisztián Gierczik, Magda Pál   +6 more
core   +1 more source

Comparative genomics and evidence for an unusual polyamine oxidation pathway in aquatic duckweed (Spirodela polyrhiza L.)

Current Plant Biology
Polyamines (PA) cellular levels are maintained through a balance between synthesis and catabolism, achieved by two classes of enzymes polyamine oxidases (PAOs) and copper amine oxidases (CuAO). Here we investigated the occurrence, molecular evolution and
Rakesh K. Upadhyay, Jonathan Shao, Grace E. Roberts, Autar K. Mattoo   +3 more
doaj   +1 more source