Results 81 to 90 of about 57,622 (148)

Functional Characterization of the P‐Type ATPases ATP13A3 and ATP13A4 as Plasma Membrane Polyamine Transporters

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
ATP13A3 and ATP13A4 mediate the plasma membrane uptake of the polyamines, putrescine and spermidine, in an ATP‐dependent manner. ATP13A3 is broadly expressed across human tissues, whereas ATP13A4 is expressed at relatively high levels in the brain and lung.
Haruka Morimoto, Tomoya Yasujima, Mione Yamasaki, Takahiro Yamashiro, Hiroaki Yuasa   +4 more
wiley   +1 more source

Heterologous expression and biochemical characterization of a polyamine oxidase from Arabidopsis involved in polyamine back conversion

, 2006
Polyamine oxidase (PAO) is a flavin adenine dinucleotide-dependent enzyme involved in polyamine catabolism. Animal PAOs oxidize spermine (Spm), spermidine (Spd), and/or their acetyl derivatives to produce H2O2, an aminoaldehyde, and Spd or putrescine ...
ROSSI M. N, FEDERICO R., PEREZ AMADOR M. A, SACCUTI G, ANGELINI, Riccardo, ROSSI MN, Angelini R, TAVLADORAKI, Paraskevi, PEREZ AMADOR MA, POLTICELLI, Fabio   +9 more
core   +1 more source

Inhibition of Polyamine Catabolism Reduces Cellular Senescence. [PDF]

Int J Mol Sci, 2023
Uemura T, Matsunaga M, Yokota Y, Takao K, Furuchi T.   +4 more
europepmc   +1 more source

Investigating effects of polyamine catabolism on epidermal differentiation

, 2019
Human skin has three layers: the epidermis, dermis and hypodermis. The epidermis in turn consists of four layers of increasingly-differentiated keratinocytes.
Ling, Blysse
core  

Genome-wide analysis of the polyamine oxidase gene family in wheat (Triticum aestivum L.) reveals involvement in temperature stress response.

PLoS ONE, 2020
Amine oxidases (AOs) including copper containing amine oxidases (CuAOs) and FAD-dependent polyamine oxidases (PAOs) are associated with polyamine catabolism in the peroxisome, apoplast and cytoplasm and play an essential role in growth and developmental ...
Fatemeh Gholizadeh, Ghader Mirzaghaderi
doaj   +1 more source

Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism

, 2007
Peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha) is an attractive candidate gene for type 2 diabetes, as genes of the oxidative phosphorylation (OXPHOS) pathway are coordinatively downregulated by reduced expression of ...
Tusa, M., Virkamaki, A., Fatrai, S., Yla-Herttuala, S., Hohtola, E., Heikkinen, S., Janne, J., Laakso, M., Koota, S., Levonen, A. L., Kuulasmaa, T., Boman, S., Parkkinen, J., Pietila, M., Pirinen, E., Kettunen, M., Niiranen, K., Kansanen, E., Smith, Ulf,, Skommer, J., Alhonen, L., Itkonen, P., Hiltunen, J. K.   +22 more
core   +1 more source

Evolution and Expression Analysis of PAO Gene Family in Cotton: Focusing on Fiber Development and Stress Response

Plants
Polyamines, a class of low-molecular-weight nitrogen-containing bases with high biological activity, are ubiquitous in organisms and play protective roles in plants under stress.
Huixin Gao, Xin Zhou, Fei Wang, Shandang Shi, Manhong Wang, Liping Zhu, Hongbin Li   +6 more
doaj   +1 more source

Nitrogen Degradation Pathways in Actinomycetes: Key Components of Primary Metabolism Ensuring Survival in the Environment

Nitrogen
Nitrogen is an essential element required for bacterial homeostasis. It serves as a building block for the biosynthesis of macromolecules and provides precursors for secondary metabolites.
Sergii Krysenko
doaj   +1 more source

POLYAMINE CATABOLISM IN ARABIDOPSIS THALIANA

, 2008
The until now characterised plant polyamine oxidases (PAO), such as the apoplastic maize PAO (ZmPAO), are involved in the terminal catabolism of spermine (Spm) and spermidine (Spd), contrary to the animal PAOs which oxidise Spm and Spd through a ...
SPEDALETTI, VALENTINA, RICCI MARIA ELENA, TAVAZZA RAFFAELA, ANGELINI, Riccardo, POMETTINI LUCIA, LEONE MARCO, FEDERICO, Rodolfo, TAVLADORAKI, Paraskevi   +7 more
core  

Polyamine-Based Pt(IV) Prodrugs as Substrates for Polyamine Transporters Preferentially Accumulate in Cancer Metastases as DNA and Polyamine Metabolism Dual-Targeted Antimetastatic Agents

, 2019
Diverse platinum drug candidates have been designed to improve inhibitory potency and overcome resistance for orthotopic tumors. However, the antimetastatic properties have rarely been reported.
Sitong Liu (3750979), Shudi Guo (8118854), Yingguang Li, Peng George Wang (256049), Hanfang Liu (5775875), Jing Ma, Kexin Yue (8118851), Peng George Wang, Xiao Zhang (152326), Songqiang Xie, Yingguang Li (5775884), Zhuoqing Xi (5775878), Xiao Zhang, Kai Feng, Songqiang Xie (1750744), Kai Feng (502124), Jianing Liu, Chaojie Wang (2175530), Chaojie Wang, Zhuoqing Xi, Sitong Liu, Jing Ma (24574), Qi Ma (141685), Hanfang Liu, Kexin Yue, Linrong Li, Qi Ma, Shudi Guo, Linrong Li (7464398), Jianing Liu (140090)   +29 more
core   +2 more sources