Results 151 to 160 of about 39,295 (245)
New Phytologist, Volume 251, Issue 1, Page 424-437, July 2026.Summary Jasmonates (JAs)‐mediated pathways are central signaling hubs in plant defense responses. However, the identification of mobile and nonmobile signals involved in downstream systemic signaling is still less studied. Here, we investigate the role of the jasmonic acid‐isoleucine (JA‐Ile) conjugating enzyme, JAR1, in shifting wound‐induced local ...
Ming Zeng, Axel Mithöfer
wiley +1 more source
DISSECTING COMPLEX POLYKETIDE BIOSYNTHESIS
Computational and Structural Biotechnology Journal, 2012 Numerous bioactive natural products are synthesised by modular polyketide synthases. These compounds can be made in high yield by native multienzyme assembly lines. However, formation of analogues by genetically engineered systems is often considerably less efficient.
openaire +4 more sources
Plant Pathology, Volume 75, Issue 4, July‐August 2026.Three Ramularia collo‐cygni strains, differing in rubellin D production, varied in virulence on two barley cultivars, with symptom development correlating with rubellin D biosynthesis in the most susceptible cultivar. The role of this phytotoxin in fungal aggressivity and possible involvement of other secondary metabolites is discussed.
Emilio Balducci +7 more
wiley +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 24, 23 June 2026.The intramolecular nitrile oxide olefin [3 + 2]‐cycloaddition offers a reliable entry toward 2‐aza‐bicyclo[4.3.0]‐nonanes, a substructure found in several bioactive piperidine alkaloids. The required oxime precursors were prepared in non‐racemic form by Ir‐catalyzed asymmetric allylation and ring‐closing metathesis.
Alicia Köcher +5 more
wiley +1 more source
A General Strategy for the Synthesis of Jerangolids Enabled by π‐allyl Stille Coupling
Chemistry – A European Journal, Volume 32, Issue 23, 16 June 2026.A general strategy for the synthesis of jerangolids is established, featuring a late‐stage π‐allyl Stille coupling of two advanced, highly customizable building blocks to form the skipped diene core. The approach provides access to all naturally occurring jerangolids, including jerangolid H, whose configuration is confirmed by NMR analysis.
Janick Schug +2 more
wiley +1 more source
Synthesis and Biosynthesis of Polyketide Natural Products [PDF]
, 2011 Traditionally separate disciplines of a large and broad chemical spectrum, synthetic organic chemistry and biochemistry have found in the last two decades a fertile common ground in the area pertaining to the biosynthesis of natural products.
Pinto, Atahualpa
core +1 more source
Rational Design of Polyketide Natural Products [PDF]
, 2005 Compounds of polyketide origin possess a wealth of pharmacological effects, including antibacterial, antifungal, antiparasitic, anticancer and immunosuppressive activities.
Kuščer, Enej +5 more
core +1 more source
Discovery and Biosynthesis of Sesquiterpene Polyketide Ester from an Atypical Terpene and Highly Reducing Polyketide Pathway. [PDF]
JACS AuChen JL, Yuan GY, Zou Y.
europepmc +1 more source
Investigating the versatility of cytochalasan cytochrome P450 monooxygenases using combinatorial biosynthesis reveals stereochemical restrictions. [PDF]
Fungal Biol BiotechnolLi L +7 more
europepmc +1 more source
Investigation of Domain-Domain Interaction between Acyl Carrier Protein and Thioesterase in Modular Polyketide Synthases. [PDF]
JACS AuXie S, Xiang C, Shin-Ya K, Zhang L.
europepmc +1 more source