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Production of a novel polyketide through the construction of a hybrid polyketide synthase
Gene, 1996The lactone rings of the polyketides platenolide and tylactone are synthesized by condensation of acetate-, proprionate-, and butyrate-derived precursors. A hybrid tylactone/platenolide synthase was constructed to determine if the choice of substrate is programmed by the polyketide synthase and to ascertain if a substrate different than that normally ...
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Catalytic Control of Spiroketal Formation in Rubromycin Polyketide Biosynthesis
Angewandte Chemie - International Edition, 2021Robin Teufel, Jörn Piel, Marina Toplak
exaly
Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms
Current Opinion in Chemical Biology, 2003Ben Shen
exaly
Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13
Cell, 2017Eric Rubin +2 more
exaly
Reconstitution of a Type II Polyketide Synthase that Catalyzes Polyene Formation
Angewandte Chemie - International Edition, 2018Yasuo Ohnishi, Kazuo Shin-ya, Danyao Du
exaly
Plant Polyketide Synthases: A fascinating group of enzymes
Plant Physiology and Biochemistry, 2009Rob Verpoorte
exaly