Results 21 to 30 of about 19,303 (227)

JC Polyomavirus Infections in Transplant Patients [PDF]

open access: yesJournal of Transplantation Technologies & Research, 2012
The polyomavirus JC virus (JCV) is a small nonenveloped DNA virus that asymptomatically infects about 80% of healthy adults and establishes latency in the kidney tissue. In case of immunodeficient hosts, JCV can lytically infect the oligodendrocytes, causing a fatal demyelinating disease, known as Progressive Multifocal Leukoencephalopathy (PML ...
S. Delbue, M. Ferraresso
openaire   +1 more source

Diagnostic Methods for and Clinical Pictures of Polyomavirus Primary Infections in Children, Finland

open access: yesEmerging Infectious Diseases, 2014
We used comprehensive serodiagnostic methods (IgM, IgG, and IgG avidity) and PCR to study Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus infections in children observed from infancy to adolescence. Comparing seroconversion
Tingting Chen   +13 more
doaj   +1 more source

Economic Evaluation of Screening for Polyomavirus Infection in Kidney Transplant Recipients: A Cost-Utility Analysis

open access: yesTransplantation Direct, 2022
Background:. Screening for polyomavirus infection after kidney transplantation is recommended by clinical practice guidelines, but cost-effectiveness of this strategy is uncertain.
Germaine Wong, PhD   +5 more
doaj   +1 more source

EFFICIENT PROPAGATION OF ARCHETYPE JC POLYOMAVIRUS IN COS-7 CELLS: EVALUATION OF REARRANGEMENTS WITHIN NCCR STRUCTURAL ORGANIZATION DURING TRANSFECTION. [PDF]

open access: yes, 2017
John Cunningham virus (JCPyV) is an ubiqui-tous human pathogen that causes disease in immunocom-promised patients. The JCPyV genome is composed of an early region and a late region, which are physically sepa-rated by the ...
Anzivino, Elena   +7 more
core   +1 more source

Polyomavirus nephropathy: Risk analysis in paired renal Transplant recipients

open access: yesBrazilian Journal of Transplantation, 2016
Polyomavirus allograft nephropathy (PVAN) has a negative impact on allograft function and survival. Analysis of paired kidneys from same donor can help to understand the role of recipient risk factors for PVAN. This analysis can also define donor related
André Barros Albuquerque Esteves   +5 more
doaj   +1 more source

Mining for viral fragments in methylation enriched sequencing data [PDF]

open access: yes, 2015
Most next generation sequencing experiments generate more data than is required for the experimental set up. For example, methyl-CpG binding domain (MBD) affinity purification based sequencing is often used for DNA-methylation profiling, but up to 30% of
Ed eSchuuring   +7 more
core   +4 more sources

Polyomavirus infections and its clinical relevance in cancer patients: A Prospective Study

open access: yesJournal of Infection and Public Health, 2017
Summary: BK and JC polyomaviruses (PyV) have been demonstrated to be associated with the pathogenesis of various human cancers. We aimed to investigate the impact of BK and JC polyomavirus infections on several clinical parameters in different human ...
Samah A. Loutfy   +6 more
doaj   +1 more source

Adverse reactions of biological therapies in patients with psoriasis [PDF]

open access: yes, 2017
Psoriasis is a chronic, immune-mediated disorder characterized by well demarcated, erythematous plaques covered by thick, silvery-white scales, most often located on the knees, elbows, sacral area and scalp.
Georgescu, Simona R.   +5 more
core   +4 more sources

Merkel Cell Polyomavirus Infection and Detection [PDF]

open access: yesJournal of Visualized Experiments, 2019
Merkel cell polyomavirus (MCPyV) infection can lead to Merkel cell carcinoma (MCC), a highly aggressive form of skin cancer. Mechanistic studies to fully investigate MCPyV molecular biology and oncogenic mechanisms have been hampered by a lack of adequate cell culture models.
Wei, Liu   +3 more
openaire   +2 more sources

Unraveling the Role of Allo-Antibodies and Transplant Injury. [PDF]

open access: yes, 2016
Alloimmunity driving rejection in the context of solid organ transplantation can be grossly divided into mechanisms predominantly driven by either T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR), though the co-existence of both ...
Matsuda, Yoshiko, Sarwal, Minnie M
core   +2 more sources

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