Construction of polyomavirus-derived pseudotype virus-like particles displaying a functionally active neutralizing antibody against hepatitis B virus surface antigen [PDF]
, 2015 Background: Virus-like particles (VLPs) can be efficiently produced by heterologous expression of viral structural proteins in yeast. Due to their repetitive structure, VLPs are extensively used for protein engineering and generation of chimeric VLPs ...
Alma Gedvilaite +5 more
core +1 more source
Efficacy and Safety of Ciprofloxacin for Prophylaxis of Polyomavirus BK Virus–Associated Hemorrhagic Cystitis in Allogeneic Hematopoietic Stem Cell Transplantation Recipients [PDF]
, 2010 Polyoma virus BK–induced hemorrhagic cystitis is an important cause of morbidity after hematopoietic stem cell transplantation (HSCT). Fluoroquinolones have been shown in vitro to inhibit BK viral replication by direct inhibition of the BK-encoded DNA ...
Bowd, Kathryn +9 more
core +2 more sources
Human Polyomavirus Infection in Renal Allograft Recipients [PDF]
BMJ, 1973 Cytological and virological studies on 74 patients with functioning renal allografts were undertaken to detect polyomavirus infection of the renal tract. Ten patients (13.5%) were excreting polyomavirus. Virus particles were seen in the electron microscope in urine samples from eight patients. B.K.
D V, Coleman, S D, Gardner, A M, Field
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Journal of Cutaneous Pathology, EarlyView.Case report of a 30‐year‐old female. Asymptomatic, red‐purple hyperplastic lesion extending from teeth 21 to 25, with bleeding upon manipulation. Differential diagnosis included: inflammatory gingival hyperplasia, plasma cell gingivitis, leukemia, and Wegener's granulomatosis.
Pedro Vinícius Santos de Jesus +8 more
wiley +1 more source
Human polyomaviruses and cancer: an overview
Clinics, 2018 The name of the family Polyomaviridae, derives from the early observation that cells infected with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised mice. Subsequent studies showed that many members of this family exhibit the
José Carlos Mann Prado +5 more
doaj +1 more source
Structural Basis and Evolution of Glycan Receptor Specificities within the Polyomavirus Family
mBio, 2020 Asymptomatic infections with polyomaviruses in humans are common, but these small viruses can cause severe diseases in immunocompromised hosts. New Jersey polyomavirus (NJPyV) was identified via a muscle biopsy in an organ transplant recipient with ...
Luisa J. Ströh +8 more
doaj +1 more source
Human polyomavirus infection: Cytological and molecular diagnosis [PDF]
Revista da Associação Médica Brasileira, 2017 Summary Few studies directly compare urinary cytology with molecular methods for detecting BK and JC polyomaviruses. Reactivation of BKV infection is the main risk factor for the development of nephropathy in immunocompromised individuals. The limitation of the cytological method can be attributed to the stage where the infected cell does not have ...
Assis, Patricia Gioia de +1 more
openaire +4 more sources
Neoadjuvant therapy in skin cancer: current evidence and future perspectives
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary The development of immune checkpoint inhibitors and targeted therapies has fundamentally changed the treatment of cutaneous malignancies, especially in squamous cell carcinoma, melanoma, and Merkel cell carcinoma. The latest neoadjuvant approaches have shown promising results in locally advanced stages.
Lea Daniello +2 more
wiley +1 more source
Viral hijacking of cellular metabolism. [PDF]
, 2019 This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James +2 more
core
Serum IgG antibodies from pregnant women reacting to mimotopes of simian virus 40 large T antigen, the viral oncoprotein [PDF]
, 2017 Simian virus 40 (SV40) large T antigen (LT) coding sequences were revealed in different human samples, whereas SV40 antibodies (Ab) were detected in human sera of cancer patients and healthy individuals, although with a lower prevalence. Previous studies
Casali, Maria V. +11 more
core +2 more sources