Results 21 to 30 of about 975 (147)
Inventive activity of the Department of Molecular Immunology of the Palladin Institute of Biochemistry of NAS of Ukraine [PDF]
The Ukrainian Biochemical Journal, 2016 The article is devoted to the inventive activity of the Department of Molecular Immunology of the Palladin Institute of Biochemistry of NAS of Ukraine in the context of the history of its inception, development and in the context of scholarly and ...
V. M. Danilova +2 more
doaj +1 more source
Natural polyreactive secretory immunoglobulin A autoantibodies as a possible barrier to infection in humans [PDF]
Infection and Immunity, 1997 Secretory immunoglobulin A (S-IgA) was investigated in human secretions for the presence of natural antibodies (Abs) acting as the first "immune barrier" to infection before induction or boosting of specific responses. These molecules could be the secretory counterpart of the natural Abs in serum that were previously shown by our laboratory to be ...
C P, Quan +4 more
openaire +2 more sources
Development of simple detection method of polyreactive secretory immunoglobulin A in saliva
The Journal of Physical Fitness and Sports Medicine, 2022 The level of secretory immunoglobulin A (SIgA) in saliva is associated with the risk of upper respiratory infection and has been identified as a condition indicator for athletes and an indicator of mucosal immune function in the elderly. In addition, it has been suggested that non-specific polyreactive SIgA is present in human saliva and colostrum. The
Sun, Ziyue +5 more
openaire +2 more sources
About the Department of Molecular Immunology, or why it is important to study immunological processes at the molecular level [PDF]
The Ukrainian Biochemical JournalThis review summarizes the scientific accomplishments of the Department of Molecular Immunology at the Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine over the period 1975–2025.
S. V. Komisarenko, S. I. Romaniuk
doaj +1 more source
Natural antibodies – facts known and unknown
Central European Journal of Immunology, 2018 In contrast to adaptive antibodies, natural antibodies are present in a non-immunised organism from birth, and they do not include anti-Gal antibodies and/or anti-Gal natural antibodies, which are developed as a result of the effect of the -Gal epitope ...
Joanna Palma +3 more
doaj +1 more source
Immunoglobulins with Non-Canonical Functions in Inflammatory and Autoimmune Disease States
, 2020 Immunoglobulins are known to combine various effector mechanisms of the adaptive and the innate immune system. Classical immunoglobulin functions are associated with antigen recognition and the initiation of innate immune responses.
Valentina N. Buneva +2 more
core +1 more source
Natural polyreactive immunoglobulin A antibodies produced in mouse Peyer’s patches
Immunology, 1999 To understand the biological function of natural immunoglobulin A (IgA) antibodies in Peyer's patches (PP), we generated IgA monoclonal antibody (mAb) clones from the PP of normal, unimmunized, specific pathogen-free BALB/c mice and examined their reactivities by enzyme-linked immunosorbent assay (ELISA). Many of these antibodies reacted with more than
M, Shimoda, Y, Inoue, N, Azuma, C, Kanno
openaire +3 more sources
British Journal of Pharmacology, EarlyView.The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley +1 more source
Medicinal Research Reviews, Volume 46, Issue 3, Page 672-712, May 2026.ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme
, 2023 International audienceIntravascular hemolysis occurs in diverse pathological conditions. Extracellular hemoglobin and heme have strong pro-oxidative and pro-inflammatory potentials that can contribute to the pathology of hemolytic diseases. However, many
Planchais, Cyril +7 more
core +1 more source