Results 101 to 110 of about 179,797 (233)

Integrating Bone‐Brain Axis Modulation and Tea Consumption for Enhancing Neurovascular Resilience and Patient Rehabilitation Education

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This figure illustrates how tea consumption and exercise metabolites may synergistically support neurovascular protection related to hemorrhagic risk. (A) Pathological mechanisms such as vascular injury, small‐vessel fragility, and impaired cerebral perfusion increase cerebrovascular vulnerability.
Yazhen Zhang, Yisheng Chen, Zhaoyuan Huang, Shizhong Zheng, Chengwan Shen, Qiangqiang Wang, Hua Chen, Shiwei He, Qing Yang, Zemin Ou, Zijin Sun, Yuzhen Xu, Guanghui Wu, Lei Huang, John H. Zhang, Zui Zou, Wangzheqi Zhang, Shaocong Zhao   +17 more
wiley   +1 more source

POMC overexpression in the ventral tegmental area ameliorates dietary obesity

, 2011
The activation of proopiomelanocortin (POMC) neurons in different regions of the brain, including the arcuate nucleus of the hypothalamus (ARC) and the nucleus of the solitary tract curtails feeding and attenuates body weight.
Daniel J Ryder, K Y Cheng, Nihal Tümer, Melanie K Judge, Alexandra Shapiro, Michael K Matheny, Yi Zhang, Lourdes M Andino, Philip J Scarpace   +8 more
core   +1 more source

Cutaneous Squamous Cell Carcinoma Amongst Solid Organ Transplant Recipients: A Systematic Review of Molecular Alterations

JEADV Clinical Practice, Volume 5, Issue 2, Page 433-457, June 2026.
ABSTRACT Background As solid organ transplantation becomes more prevalent, more patients are living on long‐term immunosuppression, greatly increasing the risk of cutaneous squamous cell carcinoma (cSCC). Although significant improvements have been achieved in the treatment of cSCC, further studies are needed to identify the specific protein expression
William Murray, Robin Caird, Michael O'Connor, Ciara Drumm, Emma O'Hora, Franklin Crossen, Aoife Lally, Aurelie Fabre, Roisin Dolan   +8 more
wiley   +1 more source

Reduced Pomc and unaltered Npy neuron number in adult Pomc^–Foxo1 mice.

, 2012
Number of Pomc-expressing (A) and Npy-expressing (B) cells per ARC hemisection in Pomc–Foxo1 mice (black bars, n = 7–9) and WT controls (white bars, n = 7–9) at the age of 15 weeks. Exemplary Pomc FISH pictures of two WT and Pomc–Foxo1 mice (C).
Domenico Accili (185429), Yitian Liu (185427), Kumiko S. Aizawa (185425), Leona Plum (27116), Hua V. Lin (185423)   +4 more
core   +1 more source

Cilia in Nervous System Development, Function, and Disease

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley   +1 more source

Uncoupling of proopiomelanocortin (POMC) fragments is related to self-injury [PDF]

, 2000
Proopiomelanocortin (POMC) contains several interesting, behaviorally active peptides. Release patterns of these fragments have been related to bizarre episodes of self-injurious behavior (SIB) among autistic individuals.
Hetrick, William, Marion, Sarah, Chicz–DeMet, Aleksandra, Talyor, Derek, Sandman, Curt A   +4 more
core   +1 more source

Effects of chronic high fat diet on mediobasal hypothalamic satiety neuron function in POMC-Cre mice

Molecular Metabolism
Objective: The prevalence of obesity has increased over the past three decades. Proopiomelanocortin (POMC) neurons in the hypothalamic arcuate nucleus (ARC) play a vital role in induction of satiety.
Özge Başer, Yavuz Yavuz, Deniz Öykü Özen, Hüseyin Buğra Özgün, Sami Ağuş, Cihan Civan Civaş, Deniz Atasoy, Bayram Yılmaz   +7 more
doaj   +1 more source

Next‐Generation Strategies for Neural Repair and Regeneration: Neural Organoid Transplantation in the CNS

Cell Proliferation, Volume 59, Issue 6, June 2026.
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang, Jinrui Li, Xingjia Mao, Wanyu Wang, Yansong Li, Xuefei Hu, Jinjie Zhong, Fengdong Zhao, Linlin Wang   +8 more
wiley   +1 more source

Electrical inhibition of identified anorexigenic POMC neurons by orexin/hypocretin.

, 2007
Proopiomelanocortin (POMC) neurons of the hypothalamic arcuate nucleus (ARC) suppress appetite, and lack of POMC-derived peptides or electrical silencing of POMC neurons causes obesity.
Ashcroft, FM, Brüning, JC, Burdakov, D, Zubcevic, L, Ma, X, Ashcroft, Frances   +5 more
core   +1 more source

Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing

Molecular Metabolism, 2017
Objective: Arcuate proopiomelanocortin (POMC) neurons are critical nodes in the control of body weight. Often characterized simply as direct targets for leptin, recent data suggest a more complex architecture.
Brian Y.H. Lam, Irene Cimino, Joseph Polex-Wolf, Sara Nicole Kohnke, Debra Rimmington, Valentine Iyemere, Nicholas Heeley, Chiara Cossetti, Reiner Schulte, Luis R. Saraiva, Darren W. Logan, Clemence Blouet, Stephen O'Rahilly, Anthony P. Coll, Giles S.H. Yeo   +14 more
doaj   +1 more source