Results 91 to 100 of about 191,601 (231)

Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons

Molecular Metabolism, 2016
Objective: Obesity is one of the primary healthcare challenges of the 21st century. Signals relaying information regarding energy needs are integrated within the brain to influence body weight.
Luke K. Burke, Barbora Doslikova, Giuseppe D'Agostino, Megan Greenwald-Yarnell, Teodora Georgescu, Raffaella Chianese, Pablo B. Martinez de Morentin, Emmanuel Ogunnowo-Bada, Celine Cansell, Lourdes Valencia-Torres, Alastair S. Garfield, John Apergis-Schoute, Daniel D. Lam, John R. Speakman, Marcelo Rubinstein, Malcolm J. Low, Justin J. Rochford, Martin G. Myers, Mark L. Evans, Lora K. Heisler   +19 more
doaj   +1 more source

The Role of Gene Flow in the Diversification of the Monkey Treefrog Complex Across the South American Dry Diagonal

Zoologica Scripta, EarlyView.
ABSTRACT Understanding Neotropical megadiversity remains challenging due to fundamental taxonomic issues, including identifying and describing cryptic species and their distribution, and the limited knowledge of key factors driving biological diversification. Such challenges are especially prominent in diverse clades with high levels of cryptic species,
Felipe Camurugi, Vinícius A. São Pedro, Felipe Magalhães, Marcelo Gehara, Eliana F. Oliveira, Gabriel C. Costa, Frank T. Burbrink, Edward A. Myers, Guarino R. Colli, Miguel T. Rodrigues, Adrian A. Garda   +10 more
wiley   +1 more source

Duzhong Fang Attenuates the POMC-Derived Neuroinflammation in Parkinsonian Mice

Journal of Inflammation Research, 2021
Lili Li,1,* Shanshan Fan,1,* Wenqi Zhang,1 Dongna Li,1 Zhen Yang,1,2 Pengwei Zhuang,1,2 Juan Han,3 Hong Guo,1 Yanjun Zhang1 1State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin ...
Li L, Fan S, Zhang W, Li D, Yang Z, Zhuang P, Han J, Guo H, Zhang Y   +8 more
doaj  

Local Approximation Schemes for Ad Hoc and Sensor Networks [PDF]

, 2005
We present two local approaches that yield polynomial-time approximation schemes (PTAS) for the Maximum Independent Set and Minimum Dominating Set problem in unit disk graphs.
Kuhn, F., Moscibroda, T., Nieberg, T., Wattenhofer, R.   +3 more
core   +4 more sources

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

IL-17A produced by POMC neurons regulates diet-induced obesity

iScience
Summary: Overeating leads to obesity, a low-grade inflammatory condition involving interleukin-17A (IL-17A). While pro-opiomelanocortin (POMC) neurons regulate feeding, their connection with IL-17A is not well understood.
Rosa Gallo, Ana Teijeiro, Mariana Angulo-Aguado, Nabil Djouder   +3 more
doaj   +1 more source

Glycometabolic Alterations in Secondary Adrenal Insufficiency: Does Replacement Therapy Play a Role? [PDF]

, 2018
Secondary adrenal insufficiency (SAI) is a potentially life-threatening endocrine disorder due to an impairment of corticotropin (ACTH) secretion from any process affecting the hypothalamus or pituitary gland.
Gianfrilli, Daniele, Graziadio, Chiara, Hasenmajer, Valeria, Isidori, Andrea M., Sbardella, Emilia, Venneri, Mary A.   +5 more
core   +2 more sources

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

High indirect bilirubin levels as an independent predictor of postoperative myasthenic crisis: a single-center, retrospective study

Frontiers in Neurology
BackgroundThymectomy is an efficient and standard treatment strategy for patients with myasthenia gravis (MG), postoperative myasthenic crisis (POMC) is the major complication related to thymectomy and has a strongly life-threatening effect.
Chao Sun, Zhe Ruan, Yu Zhang, Rongjing Guo, Huanhuan Li, Tantan Wang, Ting Gao, Yonglan Tang, Na Song, Sijia Hao, Xiaoxi Huang, Shuang Li, Fan Ning, Yue Su, Qiang Lu, Qingqing Wang, Xiangqi Cao, Zhuyi Li, Ting Chang   +18 more
doaj   +1 more source

Bovine serum albumin as the dominant form of dietary protein reduces subcutaneous fat mass, plasma leptin and plasma corticosterone in high fat-fed C57/BL6J mice [PDF]

, 2015
Acknowledgements The authors thank Harriett Schellekens from the University College Cork and Paula O’Connor from Teagasc Moorepark Food Research Centre for their assistance in procuring laboratory space and equipment.
Cotter, Paul D., Cryan, John F., Korpela, Riitta, McManus, Bettina L., Nilaweera, Kanishka N., Speakman, John R.   +5 more
core   +1 more source