Results 91 to 100 of about 189,310 (233)

High indirect bilirubin levels as an independent predictor of postoperative myasthenic crisis: a single-center, retrospective study

Frontiers in Neurology
BackgroundThymectomy is an efficient and standard treatment strategy for patients with myasthenia gravis (MG), postoperative myasthenic crisis (POMC) is the major complication related to thymectomy and has a strongly life-threatening effect.
Chao Sun, Zhe Ruan, Yu Zhang, Rongjing Guo, Huanhuan Li, Tantan Wang, Ting Gao, Yonglan Tang, Na Song, Sijia Hao, Xiaoxi Huang, Shuang Li, Fan Ning, Yue Su, Qiang Lu, Qingqing Wang, Xiangqi Cao, Zhuyi Li, Ting Chang   +18 more
doaj   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

CTB labels many non-POMC cells and few POMC cells.

, 2013
(A & B) Example images after CTB injection into the SON. (A) Low-power image in the arcuate nucleus shows POMC neurons (red) and CTB-containing neurons (green). The side of the arcuate corresponding to the side of injection (ipsilateral) has more intense
Shane T. Hentges (342798), Connie M. King (342796)   +1 more
core   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Influence of POMC-derived peptides on the adrenal gland

, 2007
Einleitung: Die normale Funktion der Nebenniere ist abhängig von der Anwesenheit von Proopiomelanokortin (POMC) und dessen Derivaten. Während die Funktion von ACTH schon lange bekannt ist, gibt es deutliche Hinweise darauf, dass auch noch andere Peptide ...
Klammer, Steffen
core   +1 more source

mTORC1-dependent increase in oxidative metabolism in POMC neurons regulates food intake and action of leptin

Molecular Metabolism, 2018
Objective: Nutrient availability modulates reactive oxygen species (ROS) production in the hypothalamus. In turn, ROS regulate hypothalamic neuronal activity and feeding behavior.
Magalie Haissaguerre, Amandine Ferrière, Vincent Simon, Nicolas Saucisse, Nathalie Dupuy, Caroline André, Samantha Clark, Omar Guzman-Quevedo, Antoine Tabarin, Daniela Cota   +9 more
doaj   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2280-2291, November 2026.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Differential contribution of POMC and AgRP neurons to the regulation of regional autonomic nerve activity by leptin

Molecular Metabolism, 2018
Objectives: The autonomic nervous system is critically involved in mediating the control by leptin of many physiological processes. Here, we examined the role of the leptin receptor (LepR) in proopiomelanocortin (POMC) and agouti-related peptide (AgRP ...
Balyssa B. Bell, Shannon M. Harlan, Donald A. Morgan, Deng-Fu Guo, Kamal Rahmouni   +4 more
doaj   +1 more source

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno, Laura Cinque, Viviana Cetrangolo, Chiara De Leonibus   +3 more
wiley   +1 more source

Effects of 6‐OHDA‐Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10459-10474, November 2026.
ABSTRACT Aims White adipose tissue (WAT) innervation by sensory and sympathetic axons contributes to tissue functions, but the consequences of selectively disrupting sympathetic input to WAT remain incompletely defined. Materials and Methods We utilised 6‐hydroxydopamine (6‐OHDA) as a validated approach to achieve bilateral sympathetic denervation of ...
Gilian Gunsch, Gargi Mishra, Magdalena Blaszkiewicz, Erica de Sousa, Jake W. Willows, Katharine W. Alltop, Annemarie Towle, Shawn Collins, Andre Khalil, Isabel F. Snodgrass, Lara Agha, Kiran Prakash, Rashmika Maganuru, Sugasini Dhavamani, John W. Newman, Kristy L. Townsend   +15 more
wiley   +1 more source