Results 91 to 100 of about 179,797 (233)

Influence of POMC-derived peptides on the adrenal gland

, 2007
Einleitung: Die normale Funktion der Nebenniere ist abhängig von der Anwesenheit von Proopiomelanokortin (POMC) und dessen Derivaten. Während die Funktion von ACTH schon lange bekannt ist, gibt es deutliche Hinweise darauf, dass auch noch andere Peptide ...
Klammer, Steffen
core   +1 more source

High indirect bilirubin levels as an independent predictor of postoperative myasthenic crisis: a single-center, retrospective study

Frontiers in Neurology
BackgroundThymectomy is an efficient and standard treatment strategy for patients with myasthenia gravis (MG), postoperative myasthenic crisis (POMC) is the major complication related to thymectomy and has a strongly life-threatening effect.
Chao Sun, Zhe Ruan, Yu Zhang, Rongjing Guo, Huanhuan Li, Tantan Wang, Ting Gao, Yonglan Tang, Na Song, Sijia Hao, Xiaoxi Huang, Shuang Li, Fan Ning, Yue Su, Qiang Lu, Qingqing Wang, Xiangqi Cao, Zhuyi Li, Ting Chang   +18 more
doaj   +1 more source

Multidisciplinary Therapy to Target Obesity and Its Complications in Adult Population: A Narrative Review

Obesity Reviews, Volume 27, Issue 7, July 2026.
ABSTRACT Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling.
Ana Raimunda Dâmaso, Flávia Campos Corgosinho, Deborah Cristina Landi Masquio, Nayra Figueiredo, Fabiana Kattah, Cintia Cercato, Lian Tock, Raquel Munhoz da Silveira Campos   +7 more
wiley   +1 more source

mTORC1-dependent increase in oxidative metabolism in POMC neurons regulates food intake and action of leptin

Molecular Metabolism, 2018
Objective: Nutrient availability modulates reactive oxygen species (ROS) production in the hypothalamus. In turn, ROS regulate hypothalamic neuronal activity and feeding behavior.
Magalie Haissaguerre, Amandine Ferrière, Vincent Simon, Nicolas Saucisse, Nathalie Dupuy, Caroline André, Samantha Clark, Omar Guzman-Quevedo, Antoine Tabarin, Daniela Cota   +9 more
doaj   +1 more source

The Role of Gene Flow in the Diversification of the Monkey Treefrog Complex Across the South American Dry Diagonal

Zoologica Scripta, Volume 55, Issue 4, Page 568-588, July 2026.
ABSTRACT Understanding Neotropical megadiversity remains challenging due to fundamental taxonomic issues, including identifying and describing cryptic species and their distribution, and the limited knowledge of key factors driving biological diversification. Such challenges are especially prominent in diverse clades with high levels of cryptic species,
Felipe Camurugi, Vinícius A. São Pedro, Felipe Magalhães, Marcelo Gehara, Eliana F. Oliveira, Gabriel C. Costa, Frank T. Burbrink, Edward A. Myers, Guarino R. Colli, Miguel T. Rodrigues, Adrian A. Garda   +10 more
wiley   +1 more source

Development of a Brain‐Penetrant Nurr1 Agonist Tool

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
Nuclear receptor‐related 1 (Nurr1) is a ligand‐activated transcription factor with neuroprotective properties, thought to hold therapeutic potential in neurodegeneration. Here, we developed a potent, brain‐penetrant Nurr1 agonist to study the effects of pharmacological Nurr1 activation in the CNS in vivo. The ligand‐sensing transcription factor nuclear
Jan Vietor, Tanja Stiller, Christian Gege, Wael Saeb, Úrsula López‐García, Hella Kohlhof, Daniel Vitt, Daniel Merk   +7 more
wiley   +1 more source

Differential contribution of POMC and AgRP neurons to the regulation of regional autonomic nerve activity by leptin

Molecular Metabolism, 2018
Objectives: The autonomic nervous system is critically involved in mediating the control by leptin of many physiological processes. Here, we examined the role of the leptin receptor (LepR) in proopiomelanocortin (POMC) and agouti-related peptide (AgRP ...
Balyssa B. Bell, Shannon M. Harlan, Donald A. Morgan, Deng-Fu Guo, Kamal Rahmouni   +4 more
doaj   +1 more source

ASIP Variants in Livestock: It's Not Black and White

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Fur and feather pigmentation play an important role in the survival and reproduction of many species, as well as in selective breeding and agriculture. The synthesis of pigment molecules, eumelanin and pheomelanin, is partially regulated by the agouti signalling protein (ASIP) encoded by the ASIP gene.
Isabella M. Brown, Kylie A. Munyard
wiley   +1 more source

POMC及UCP3基因多形性與台灣學童肥胖相關性之研究

, 2012
[[abstract]]Background: Human Uncoupling Protein 3 (UCP3) is a new candidate gene for human obesity. UCPJ has been shown to be regulated by thyroid hormone, 3-adrenergic agonists, leptin, and fat feeding in rodents. Mutations in exon 3 (V1O2I) and exon 4
Chen, Chih-Mei; Liu, Chiu-Shong; Wang, Nancy M. ; Lin, Cheng-Chieh
core  

POMC gene expression in mouse and hamster melanoma cells

, 1991
Expression of mRNA hybridizable to murine POMC cDNA, and immunoreactivity specific for POMC derived peptide, β-endorphin, are reported for the first time in one murine and two hamster melanoma lines. The apparent sizes of POMC mRNA transcript were 3.5, 1.
Andrzej Slominski, Slominski, Andrzej
core   +1 more source