Results 31 to 40 of about 189,310 (233)

Central Dicer-miR-103/107 controls developmental switch of POMC progenitors into NPY neurons and impacts glucose homeostasis

eLife, 2018
Proopiomelanocortin (POMC) neurons are major negative regulators of energy balance. A distinct developmental property of POMC neurons is that they can adopt an orexigenic neuropeptide Y (NPY) phenotype.
Sophie Croizier, Soyoung Park, Julien Maillard, Sebastien G Bouret   +3 more
doaj   +1 more source

Growing Up POMC: Pro-opiomelanocortin in the Developing Brain [PDF]

, 2011
Neurons in the arcuate nucleus of the hypothalamus (ARH) play a central role in the regulation of body weight and energy homeostasis. ARH neurons directly sense nutrient and hormonal signals of energy availability from the periphery and relay this ...
Padilla, Stephanie Louise
core   +1 more source

60 YEARS OF POMC: N-terminal POMC peptides and adrenal growth [PDF]

Journal of Molecular Endocrinology, 2016
The peptide hormones contained within the sequence of proopiomelanocortin (POMC) have diverse roles ranging from pigmentation to regulation of adrenal function to control of our appetite. It is generally acknowledged to be the archetypal hormone precursor, and as its biology has been unravelled, so too have many of the basic principles of hormone ...
openaire   +2 more sources

Stocking density affects transcriptome changes in the hypothalamic-pituitary-gonadal axis and reproductive performance in ducks

Italian Journal of Animal Science, 2022
The hypothalamic-pituitary-adrenal (HPA) axis and hypothalamic-pituitary-gonadal (HPG) axis plays a central role in mediating physiological responses related to the reproductive system under any stressful condition.
Hehe Liu, Xia Xiong, Fajun Pu, Jianmei Wang, Yanying Li, Yang Xi, Shengchao Ma, Lili Bai, Rongping Zhang, Li Liang, Chaowu Yang   +10 more
doaj   +1 more source

Epigenetic Alterations of the Promoter Region of the POMC Gene in Adolescent Depressive Disorder Patients with Nonsuicidal Self-injury Behaviors

Psychology Research and Behavior Management, 2020
Doudou Zheng,1,* Xiaojiao Bi,2,* Tianliang Zhang,3 Chao Han,3 Tantan Ma,3 Lina Wang,2 Mengmeng Sun,3 Kaiyan Cui,3 Limin Yang,3 Lanfen Liu3 1Department of Psychiatry, School of Clinical Medicine, Cheeloo College of Medicine, Shandong University, Jinan ...
Zheng D, Bi X, Zhang T, Han C, Ma T, Wang L, Sun M, Cui K, Yang L, Liu L   +9 more
doaj  

Whole-brain Mapping of the Direct Inputs and Axonal Projections of Pro-opiomelanocortin(POMC) and Agouti-related peptide(AgRP) Neurons

Frontiers in Neuroanatomy, 2015
Pro-opiomelanocortin (POMC) neurons in the arcuate nucleus (ARC) of the hypothalamus and nucleus tractus solitarius (NTS) of the brainstem play important roles in suppressing food intake and maintaining energy homeostasis.
Daqing ewang, Daqing ewang, Xiaobing eHe, Xiaobing eHe, Zhe ezhao, Qiru eFeng, Rui eLin, Yue eSun, Ting eDing, Fuqiang eXu, Fuqiang eXu, Fuqiang eXu, Minmin eLuo, Minmin eLuo, Cheng eZhan   +14 more
doaj   +1 more source

60 YEARS OF POMC: Transcriptional and epigenetic regulation of POMC gene expression [PDF]

Journal of Molecular Endocrinology, 2016
Expression of the pro-opiomelanocortin ( POMC ) gene integrates numerous inputs that reflect the developmental history of POMC-expressing cells of the pituitary and hypothalamus, as well as their critical role in the endocrine system.
openaire   +2 more sources

Proopiomelanocortin (POMC)–β‐Endorphin System in the Rat Colon: Expression, Up Regulation by Stress, and Correlation With Stress‐Induced Visceral Analgesia [PDF]

Neurogastroenterol Motil
This study identified a functional proopiomelanocortin–β‐endorphin system in the rat colon. Peripheral CRF and repeated water avoidance stress increased colonic POMC expression, which was associated with reduced visceral pain. These findings suggest that, outside the pituitary, a CRF‐ and stress‐sensitive enteric POMC–β‐endorphin system may help ...
Yuan P, Larauche M, Wu V, Taché Y.
europepmc   +2 more sources

Defining POMC Neurons Using Transgenic Reagents: Impact of Transient Pomc Expression in Diverse Immature Neuronal Populations

, 2012
Melanocortin signaling plays a central role in the regulation of phenotypes related to body weight and energy homeostasis. To specifically target and study the function of proopiomelanocortin (POMC) neurons, Pomc promoter elements have been utilized to ...
Lori M. Zeltser, Daniel Reef, Stephanie L. Padilla   +2 more
core   +1 more source

Expression of pituitary POMC gene and release of pituitary POMC-derived peptides in cell lines HaCaT and Colo 679 [PDF]

, 2006
Über die Expression des hypophysären POMC-Gens und die Bildung und Freisetzung von hypophysären POMC-Derivaten in der Hypophyse des Menschen liegen viele Informationen vor.
Tschischka, Marcus
core   +1 more source