Results 51 to 60 of about 179,797 (233)

POMC. Toward a model checking tool for operator precedence languages [PDF]

, 2020
LAUREA MAGISTRALEUn importante contributo da parte del campo dei metodi formali è quello di fornire agli ingegneri del software strumenti sempre più potenti ed efficienti per modellare, analizzare e verificare le proprietà ed il comportamento dei ...
Bergamaschi, Davide
core  

Selecting Promising Soil Quality Indicators for Monitoring Soil Management Effects Based on 10 European Long‐Term Field Experiments

Journal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Background: Soil quality can be measured through soil quality indicators that reflect soil processes. Aim: The aim of this study was to (1) identify a limited set of soil quality indicators that are most sensitive to agricultural soil management and that are widely applicable regardless of pedo‐climatic conditions, and (2) link common ...
Giulia Bongiorno, Marie Wesselink, Wim van den Berg, Zhanguo Bai, Ron de Goede, Carla Sofia Santos Ferreira, Luuk Fleskens, Matjaz Glavan, Wiepie Haagsma, Paul Mäder, Alicia Morugan‐Coronado, Harry Verstegen, Zoltan Toth, Wijnand Sukkel, Else K. Bünemann   +14 more
wiley   +1 more source

Defining POMC Neurons Using Transgenic Reagents: Impact of Transient Pomc Expression in Diverse Immature Neuronal Populations

, 2012
Melanocortin signaling plays a central role in the regulation of phenotypes related to body weight and energy homeostasis. To specifically target and study the function of proopiomelanocortin (POMC) neurons, Pomc promoter elements have been utilized to ...
Lori M. Zeltser, Daniel Reef, Stephanie L. Padilla   +2 more
core   +1 more source

Fetal alcohol exposure alters proopiomelanocortin gene expression and hypothalamic-pituitary-adrenal axis function via increasing MeCP2 expression in the hypothalamus. [PDF]

PLoS ONE, 2014
Proopiomelanocortin (POMC) is a precursor gene of the neuropeptide β-endorphin in the hypothalamus and is known to regulate various physiological functions including stress response.
Omkaram Gangisetty, Rola Bekdash, George Maglakelidze, Dipak K Sarkar   +3 more
doaj   +1 more source

Cutaneous Pigmentary Changes During Setmelanotide Therapy: Dermoscopic and Confocal Findings in Two Patients

JEADV Clinical Practice, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4 receptor agonist approved for the treatment of rare forms of genetic obesity. Through off‐target activation of the melanocortin‐1 receptor, it may induce cutaneous pigmentation changes; however, data regarding its effects on melanocytic nevi remain limited.
Martina Cavicchi, Claudia Lasagni, Silvana Ciardo, Francesca Giusti, Albino Eccher, Caterina Longo   +5 more
wiley   +1 more source

Myasthenia Gravis and Thymoma

Muscle &Nerve, EarlyView.
ABSTRACT Thymoma is the most common tumor of the anterior mediastinum. Approximately 20%–30% of patients with a thymoma develop myasthenia gravis (MG), and an additional one third may possess positive acetylcholine receptor (AChR) antibodies without MG.
Benjamin Claytor, Lukas Delasos, Daniel P. Raymond, Erik Seroogy, Jason Lempel, Yuebing Li   +5 more
wiley   +1 more source

Effectiveness and Safety of Setmelanotide in a Patient With a Heterozygous PCSK1 Deficiency

Obesity, EarlyView.
ABSTRACT Setmelanotide, a melanocortin 4 receptor (MC4R) agonist, is a promising pharmacological treatment option for people with rare monogenic obesity conditions affecting the leptin‐melanocortin signaling pathway, including proprotein convertase subtilisin/kexin type 1 (PCSK1) gene mutations.
Ellina Lytvyak, Arshdeep Rattol, Eduardo Grunvald   +2 more
wiley   +1 more source

Conditional expression of Pomc in the Lepr-positive subpopulation of POMC neurons is sufficient for normal energy homeostasis and metabolism [PDF]

, 2015
Peptides derived from the proopiomelanocortin (POMC) precursor are critical for the normal regulation of many physiological parameters, and POMC deficiency results in severe obesity and metabolic dysfunction.
Rubinstein, Marcelo, Myers Jr, Martin G., Mercer, Aaron J., Lam, Daniel D., Low, Malcolm J., Attard, Courtney A.   +5 more
core   +1 more source

Genetic features of hormonal regulation of energy metabolism (literature review)

Актуальні проблеми сучасної медицини, 2019
Summary: Many chronic diseases are associated with impaired human energy metabolism and its hormonal regulation. According to the WHO, there are more than 300 million people with obesity in the world, 24.1% of the population are suffering from obesity in
Taisiia, Olena, Olena
doaj  

Age-Dependent Changes in the mRNA Levels of Neuropeptide Y, Proopiomelanocortin, and Corticotropin-Releasing Factor in the Hypothalamus in Growing Broiler Chicks

The Journal of Poultry Science, 2013
Lines of evidence suggest that hypothalamic neuropeptides have a physiological role in the regulation of food intake in mammals. However, little is known about the age-dependent change of hypothalamic neuropeptides in chicks.
Takaoki Saneyasu, Kiwako Nakanishi, Hiroyuki Atsuta, Atsushi Ikura, Hiroshi Kamisoyama, Shin Hasegawa, Kazuhisa Honda   +6 more
doaj   +1 more source