Results 71 to 80 of about 239,644 (300)

Higher risk of zinc deficiency in New Zealand Pacific school children compared with their Māori and European counterparts: a New Zealand national survey. [PDF]

, 2010
Few multi-ethnic national surveys have examined Zn nutriture, despite its importance for optimal growth and development during childhood. We assessed the Zn status of urban and semi-urban children aged 5-15 years from three ethnic groups in New Zealand ...
Karl B. Bailey, Noela Wilson, Wilson, Noela, Parnell, Winsome R, Rosalind S. Gibson, Gibson, Rosalind S, Bailey, Karl B, Elaine L. Ferguson, Ferguson, Elaine L, Winsome R. Parnell   +9 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Prevalence and risk factors for self-reported diabetes among adult men and women in India: findings from a national cross-sectional survey. [PDF]

, 2011
OBJECTIVE: We examined the distribution of diabetes and modifiable risk factors to provide data to aid diabetes prevention programmes in India. DESIGN: Population-based cross-sectional survey of men and women included in India's third National Family ...
Agrawal, Sutapa, Agrawal, S, Shah Ebrahim, Ebrahim, Shah, Ebrahim, S, Sutapa Agrawal   +5 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Dietary intake and anthropometric reference values in population studies

, 2015
In nutritional epidemiology it is essential to have reference values for nutrition and anthropometry in order to compare individual and population data.With respect to reference nutritional intake, the new concept of Dietary Reference Intakes is ...
Ribas, Lourdes, Serra-Majem, Luis, Rodrigo, Carmen Pérez, Arija, Victoria, de Vitoria, Emilio Martínez, Ortega, Rosa M., Aranceta, Javier   +6 more
core   +1 more source

Alcohol intake and risk of colorectal cancer: results from the UK Dietary Cohort Consortium. [PDF]

, 2010
BACKGROUND: Epidemiological studies have suggested that excessive alcohol intake increases colorectal cancer (CRC) risk. However, findings regarding tumour subsites and sex differences have been inconsistent.
Khaw, K-T, Keogh, R. H., Park, J. Y., R H Keogh, Greenwood, DC, Burley, V. J., D Kuh, Rodwell, SA, Kuh, D., R N Luben, A A Mulligan, Fentiman, I. S., Fentiman, Ian, Dahm, C. C., Mishra, GD, I R White, Shipley, MJ, Shipley, M. J., Mishra, G. D., J Y Park, Cade, J. E., M J Shipley, Brunner, E. J., Luben, RN, Cairns, Benjamin, Dahm, CC, K-T Khaw, Rodwell, S. A., Stephen, AM, S A Rodwell, Mitrou, PN, Burley, VJ, Fentiman, IS, Khaw, K. T., P N Mitrou, Greenwood, D. C., Keogh, RH, Luben, R. N., E J Brunner, Cairns, BJ, Mulligan, AA, Mitrou, P. N., Park, JY, Spencer, Elizabeth, I S Fentiman, D C Greenwood, B J Cairns, Cade, JE, Brunner, EJ, V J Burley, Stephen, A. M., White, IR, A M Stephen, Mulligan, A. A., Kuh, D, E A Spencer, J E Cade, C C Dahm, G D Mishra, Cairns, B. J., Spencer, E. A., Khaw, KT, White, I. R., Spencer, EA   +63 more
core   +1 more source

Historical intake and elimination of polychlorinated biphenyls and organochlorine pesticides by the Australian population reconstructed from biomonitoring data

Environment International, 2015
Quantifying the competing rates of intake and elimination of persistent organic pollutants (POPs) in the human body is necessary to understand the levels and trends of POPs at a population level.
Qingwei Bu, Matthew MacLeod, Fiona Wong, Leisa-Maree L. Toms, Jochen F. Mueller, Gang Yu   +5 more
doaj   +1 more source

A Statistical Approach for Estimating the Distribution of Usual Dietary Intake to Assess Nutritionally At-Risk Populations Based on the New Japanese Dietary Reference Intakes (DRIs)

Journal of Nutritional Science and Vitaminology, 2007
The health of individuals is not markedly affected by the nutrients ingested in a single day; rather it is influenced by dietary habits over a long period of time. However, it is impossible to survey usual intake directly because recording diet over a long period of time is burdensome for the subjects, so usual dietary intake is rarely measured ...
ISHIWAKI, Asako, YOKOYAMA, Tetsuji, FUJII, Hiroko, SAITO, Kyoko, NOZUE, Miho, YOSHITA, Katsushi, YOSHIIKE, Nobuo   +6 more
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source