Results 61 to 70 of about 239,644 (300)

Semi-supervised learning for genomic prediction of novel traits with small reference populations: an application to residual feed intake in dairy cattle [PDF]

Genetics Selection Evolution, 2016
Genomic prediction for novel traits, which can be costly and labor-intensive to measure, is often hampered by low accuracy due to the limited size of the reference population. As an option to improve prediction accuracy, we introduced a semi-supervised learning strategy known as the self-training model, and applied this method to genomic prediction of ...
Yao, Chen, Zhu, Xiaojin, Weigel, Kent A.
openaire   +2 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Scientific Opinion on Dietary Reference Values for biotin [PDF]

EFSA Journal, 2014
Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies (NDA) derived Dietary Reference Values (DRVs) for biotin.
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Dietary Intake of Vitamin D in the Czech Population: A Comparison with Dietary Reference Values, Main Food Sources Identified by a Total Diet Study [PDF]

Nutrients, 2018
The usual dietary intake of vitamin D was studied in 10 subgroups of the Czech population. Food consumption data was collected using repeated 24 h recall in a national cross-sectional survey (the Study of Individual Food Consumption, SISP04), and the vitamin D content in marketed foods was quantified within the national Total Diet Study (2014–2015 ...
Svatava Bischofova, Marcela Dofkova, Jitka Blahova, Radek Kavrik, Jana Nevrla, Irena Rehurkova, Jiri Ruprich   +6 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Predicting urinary creatinine excretion and its usefulness to identify incomplete 24h urine collections

, 2012
Studies using 24 h urine collections need to incorporate ways to validate the completeness of the urine samples. Models to predict urinary creatinine excretion (UCE) have been developed for this purpose; however, information on their usefulness to ...
Dekkers, A.L.M., Rehurkova, I., Veer, P., van 't, de Boer, E., Keyzer, W., de, de Henauw, S., Crispim, S.P., de Keyzer, W., van 't Veer, P., Maele, G., van, Volatier, J.L., Slimani, N., Boer, E., de, Huybrechts, I., Ruprich, J., Hulshof, P.J.M., Andersen, L.F., van Maele, G., Geelen, A., Henauw, S., de   +19 more
core   +1 more source

Simulation of the fruit and vegetable intakes meeting the dietary reference intakes of Japanese adults from the National Health and Nutrition Survey

Scientific Reports
Fruit and vegetable intake has been associated with a reduced risk of noncommunicable diseases, however, few studies have assessed the necessary intake of fruits and vegetables to meet nutrient reference values for the dietary reference intake.
Mai Matsumoto, Emiko Okada, Xiaoyi Yuan, Chika Okada, Mayu Kikukawa, Mieko Nakamura, Hidemi Takimoto   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Discussion on protein recommendations for supporting muscle and bone health in older adults: a mini review

Frontiers in Nutrition
Muscle and bone tissues are interconnected, and both rely on an adequate protein intake. Recommendations for protein intake for older adults specifically vary across countries.
Inge Groenendijk, Lisette C. P. G. M. de Groot, Inge Tetens, Pol Grootswagers   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source