Results 61 to 70 of about 3,386 (182)
Virological Characterization of Pigs with Erythema Multiforme
Microorganisms, 2022 Erythema multiforme in pigs is an acute, self-limiting disease characterized by red skin areas and often associated with anorexia, fever and respiratory problems. The cause of the disease remains unknown.
Sabrina Halecker +5 more
doaj +1 more source
Evidence for Microchimerism in Baboon Recipients of Pig Hearts
Viruses, 2023 Xenotransplantation, like allotransplantation, is usually associated with microchimerism, i.e., the presence of cells from the donor in the recipient.
Hina Jhelum +10 more
doaj +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Xenotransplantation, EarlyView., 2020 Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Determinants of High Titer in Recombinant Porcine Endogenous Retroviruses [PDF]
Journal of Virology, 2004 ABSTRACT Porcine endogenous retroviruses (PERVs) pose a potential stumbling block for therapeutic xenotransplantation, with the greatest threat coming from viruses generated by recombination between members of the PERV subgroup A (PERV-A) and PERV-C families (PERV-A/C recombinants).
Ian, Harrison +3 more
openaire +2 more sources
Genome-wide inactivation of porcine endogenous retroviruses (PERVs) [PDF]
Science, 2015 Virally cleansing the pig genome Transplants from pigs could be a solution to a shortage of human organs for transplantation. Unfortunately, porcine endogenous retroviruses (PERVs) are rife in pigs and can be transmitted to humans, risking disease. L. Yang et al.
Yang, Luhan +13 more
openaire +4 more sources
Transmission of Porcine Endogenous Retrovirus Produced from Different Recipient Cells In Vivo. [PDF]
PLoS ONE, 2016 Humanized pigs have been developed to reduce the incidence of immune rejection in xenotransplantation, but significant concerns remain, such as transmission of viral zoonosis. Porcine endogenous retroviruses (PERV), which exist in the genome of pigs, are
Nayoung Kim +7 more
doaj +1 more source
Journal of Virology, 2023 Yucatan SLAD/D haplotype miniature swine are candidates as organ donors for xenotransplantation. A full-length replication-competent PERV-C provirus was characterized. The provirus was chromosomally mapped in the pig genome.
Michael Rodrigues Costa +5 more
semanticscholar +1 more source
Journal of the Korea Academia-Industrial cooperation Society, 2023 Pigs are widely considered donor animals for xenotransplantation to solve the critical issue of human donor organ shortage. However, the risk of zoonosis needs to be overcome during xenotransplantation.
Sang-Eun Kim +4 more
semanticscholar +1 more source
Viruses, 2016 Transspecies transmission of retroviruses is a frequent event, and the human immunodeficiency virus-1 (HIV-1) is a well-known example. The gibbon ape leukaemia virus (GaLV) and koala retrovirus (KoRV), two gammaretroviruses, are also the result of a ...
Joachim Denner
doaj +1 more source
The prevention strategies of swine viruses related to xenotransplantation
Virology Journal, 2023 Xenotransplantation is considered a solution for the shortage of organs, and pigs play an indispensable role as donors in xenotransplantation. The biosecurity of pigs, especially the zoonotic viruses carried by pigs, has attracted attention.
Hongzhen Mao +5 more
doaj +1 more source