Results 41 to 50 of about 517,815 (166)
The porcine virome and xenotransplantation
Virology Journal, 2017 The composition of the porcine virome includes viruses that infect pig cells, ancient virus-derived elements including endogenous retroviruses inserted in the pig chromosomes, and bacteriophages that infect a broad array of bacteria that inhabit pigs ...
Joachim Denner
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The detection and role of human endogenous retroviruses in multiple sclerosis and other neurological diseases [PDF]
, 2009 A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Master of PhilosophyHuman endogenous retroviruses (HERVs) are estimated to form approximately 5% of the human genome.
Smith, Richard G.
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Transmission of Porcine Endogenous Retrovirus Produced from Different Recipient Cells In Vivo. [PDF]
PLoS ONE, 2016 Humanized pigs have been developed to reduce the incidence of immune rejection in xenotransplantation, but significant concerns remain, such as transmission of viral zoonosis. Porcine endogenous retroviruses (PERV), which exist in the genome of pigs, are
Nayoung Kim +7 more
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Complex evolution of porcine endogenous retroviruses [PDF]
, 2019 Abstract Background: Porcine endogenous retroviruses (PERVs) are proviruses that can replicate in human cells. However, the evolutionary process leading to the generation of modern PERVs is not well understood.Results: We mined 14 pig genomes and other available 304 mammalian genomes in silico, which led to the documentation of 185 full-length ...
Yicong Chen +3 more
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Genome-wide inactivation of porcine endogenous retroviruses (PERVs) [PDF]
Science, 2015 Virally cleansing the pig genome Transplants from pigs could be a solution to a shortage of human organs for transplantation. Unfortunately, porcine endogenous retroviruses (PERVs) are rife in pigs and can be transmitted to humans, risking disease. L. Yang et al.
Yang, Luhan +13 more
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Epigenetic marking and repression of porcine endogenous retroviruses
Journal of General Virology, 2013 Endogenous retroviruses (ERVs) are remnants of retroviral germ line infections and have been identified in all mammals investigated so far. Although the majority of ERVs are degenerated, some mammalian species, such as mice and pigs, carry replication-competent ERVs capable of forming infectious viral particles.
Wolf, Gernot +3 more
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Evolutionary Spread and Recombination of Porcine Endogenous Retroviruses in the Suiformes [PDF]
Journal of Virology, 2005 ABSTRACT Different Suiformes with increasing phylogenetic distance to the common pig ( Sus scrofa ) were assayed for the presence of porcine endogenous retroviruses (PERV) in general ( pol gene), while the distribution of long terminal repeat (LTR) types ...
Niebert, Marcus, Tonjes, Ralf R.
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Viruses, 2016 Transspecies transmission of retroviruses is a frequent event, and the human immunodeficiency virus-1 (HIV-1) is a well-known example. The gibbon ape leukaemia virus (GaLV) and koala retrovirus (KoRV), two gammaretroviruses, are also the result of a ...
Joachim Denner
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The prevention strategies of swine viruses related to xenotransplantation
Virology Journal, 2023 Xenotransplantation is considered a solution for the shortage of organs, and pigs play an indispensable role as donors in xenotransplantation. The biosecurity of pigs, especially the zoonotic viruses carried by pigs, has attracted attention.
Hongzhen Mao +5 more
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Endogenous betaretroviruses of sheep: teaching new lessons in retroviral interference and adaptation [PDF]
, 2004 The endogenous betaretroviruses of small ruminants offer an excellent model to investigate the biological relevance of endogenous retroviruses (ERVs). Approximately twenty copies of endogenous betaretroviruses (enJSRVs) are present in the genome of sheep
Palmarini, M., Mura, M., Spencer, T.E.
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