Results 91 to 100 of about 6,865 (203)

Delayed postconditioning with a series of ipsilateral CCA occlusion and reperfusion reduced infarction.

, 2013
A. Comparative timelines for delayed postconditioning, in which postconditioning was conducted by occluding or releasing the ipsilateral CCA alone. Delayed postconditioning was performed by 6 cycles of occluding or releasing the left CCA alone; each ...
Chuancheng Ren (333501), Heng Zhao (333503), Xuwen Gao (375540), Zhimin Yan (375541), Xiaoyuan Chen (322516), Gang Niu (133768)   +5 more
core   +1 more source

Sevoflurane postconditioning enhanced hippocampal neuron resistance to global cerebral ischemia induced by cardiac arrest in rats through PI3K/Akt survival pathway

Frontiers in Cellular Neuroscience, 2016
The purpose of this current study is to evaluate whether improvement of mitochondrial dysfunction was involved in the therapeutic effect of sevoflurane postconditioning in global cerebral ischemia after cardiac arrest (CA) via the PI3K/Akt pathway.
Zhihua Wang, Zhi Ye, Guoqing Huang, Na Wang, E Wang, Qulian Guo   +5 more
doaj   +1 more source

Nanotoxicology of Dendrimers in the Mammalian Heart: ex vivo and in vivo Administration of G6 PAMAM Nanoparticles Impairs Recovery of Cardiac Function Following Ischemia-Reperfusion Injury

International Journal of Nanomedicine, 2020
Fawzi Babiker,1 Ibrahim F Benter,2 Saghir Akhtar3 1Department of Physiology, Faculty of Medicine, Health Science Center, Kuwait University, Kuwait City, Kuwait; 2Faculty of Medicine, Eastern Mediterranean University, Famagusta, North Cyprus, Republic of ...
Babiker F, Benter IF, Akhtar S
doaj  

Histone deacetylases exert class specific roles in conditioning the brain and heart against acute ischemic injury.

Frontiers in Neurology, 2015
Ischemia-reperfusion (IR) injury comprises a significant portion of morbidity and mortality from heart and brain diseases worldwide. This enduring clinical problem has inspired myriad reports in the scientific literature of experimental interventions ...
Sverre Erik Aune, Daniel J Herr, Craig J Kutz, Donald R Menick   +3 more
doaj   +1 more source

Effects of sevoflurane and ischemic postconditioning on apoptosis expressed as a percent of total nuclei in tissue sections from rat hearts exposed to ischemia-reperfusion (TUNEL staining, 400×).

, 2013
TUNEL-positive nuclei (brown nuclei) was indicated by the arrow. a normocholesterolemic ischemia reperfusion group (IR), b normocholesterolemic sevoflurane postconditioning group (IR + SPO), c normocholesterolemic ischemic postconditioning group (IR ...
Can-Can Wang (466786), Chen Zhou (466781), Fei-Jiang Zhang (466782), Jian-An Wang (466788), Lei-Lei Ma (466780), Ling-Bo Qian (466785), Fei-Juan Kong (466783), Min Yan (119568), Yong Xu (17491), Xian-Bao Liu (466787), Wen-Na Wang (466784)   +10 more
core   +1 more source

Delayed postconditioning with a series of bilateral CCA occlusion and reperfusion reduced infarction.

, 2013
A. The diagram shows the protocols to compare the protective effects of rapid and delayed postconditioning, in which postconditioning was carried out by occluding or releasing the bilateral CCA.
Chuancheng Ren (333501), Heng Zhao (333503), Xuwen Gao (375540), Zhimin Yan (375541), Xiaoyuan Chen (322516), Gang Niu (133768)   +5 more
core   +1 more source

Ischemic Postconditioning Protects Neuronal Death Caused by Cerebral Ischemia and Reperfusion via Attenuating Protein Aggregation

International Journal of Medical Sciences, 2012
Objective: To investigate the effect of ischemic postconditioning on protein aggregation caused by transient ischemia and reperfusion and to clarify its underlying mechanism.Methods: Two-vessel-occluded transient global ischemia rat model was used.
Jianmin Liang, Jihang Yao, Guangming Wang, Ying Wang, Boyu Wang, Pengfei Ge
doaj  

Temporal Exercise Conditioning Confers Dual-Phase Cardioprotection Against Isoproterenol-Induced Injury in a Rat Model

Antioxidants
Exercise training has demonstrated potential benefits in addressing the adverse effects of cardiovascular diseases, particularly myocardial infarction (MI). This study analyzed the cardioprotective effects of moderate exercise before and after MI in rats
Krisztina Kupai, Zsolt Murlasits, Hsu Lin Kang, Eszter Regős, Ákos Várkonyi, Csaba Lengyel, Imre Pávó, Zsolt Radák, Béla Juhász, Dániel Priksz, Anikó Pósa   +10 more
doaj   +1 more source

A novel perspective in stroke neuroprotection: Leveraging hypoxic pocket insights for studying preconditioning and postconditioning

Neuroprotection
This perspective article delineates the significant role of hypoxic pockets—localized, transient reductions in cerebral oxygenation—and their implications for stroke neuroprotection strategies. It posits that preconditioning and postconditioning, through
Heng Zhao, Yan Meng, Sijie Li, Guiyou Liu, Xunming Ji   +4 more
doaj   +1 more source

In vivo and in vitro characterization of a novel neuroprotective strategy for stroke: ischemic postconditioning

, 2008
As clinical trials of pharmacological neuroprotective strategies in stroke have been disappointing, attention has turned to the brain's own endogenous strategies for neuroprotection.
Ordonez AN, Gala R, Xiong Z, Simon RP, PIGNATARO, GIUSEPPE, Meller R, Inoue K, Ashley MD   +7 more
core   +1 more source