Results 81 to 90 of about 6,865 (203)

Ischemic postconditioning alters the gene expression pattern of the ischemic heart

open access: yes, 2018
To profile changes in gene expression in response to ischemic postconditioning, isolated rat hearts were subjected to 30 min of regional ischemia followed by 120 min of reperfusion with or without postconditioning.
Bencsik, Péter   +7 more
core   +1 more source

Interaction of ischaemic postconditioning and thrombectomy in patients with ST-elevation myocardial infarction

open access: yes, 2020
Objective The Third Danish Study of Optimal Acute Treatment of Patients with ST-segment Elevation Myocardial Infarction - Ischaemic Postconditioning (DANAMI-3-iPOST) did not show improved clinical outcome in patients with ST-segment elevation myocardial ...
Joshi, Francis   +20 more
core   +1 more source

Postconditioning signalling in the heart: mechanisms and translatability [PDF]

open access: yes, 2015
The protective effect of ischaemic postconditioning (short cycles of reperfusion and reocclusion of a previously occluded vessel) was identified over a decade ago commanding intense interest as an approach for modifying reperfusion injury which ...
Baxter, Gary Francis, Bice, Justin S.
core   +1 more source

A Double-Edged Sword: Volatile Anesthetic Effects on the Neonatal Brain

open access: yesBrain Sciences, 2014
The use of volatile anesthetics, a group of general anesthetics, is an exceedingly common practice. These anesthetics may have neuroprotective effects. Over the last decade, anesthetic induced neurotoxicity in pediatric populations has gained a certain ...
Sunny Chiao, Zhiyi Zuo
doaj   +1 more source

THE ROLE OF HYPOXIA-INDUCED FACTOR-1 (HIF-1) IN CYTOPROTECTION EFFECT IN ISCHEMIC AND PHARMACOLOGIC POSTCONDITIONING

open access: yesРоссийский кардиологический журнал, 2014
The review concerns on the experimental studies results of the influence of ischemic and pharmacological post conditioning of the liver, brain, myocardium and scelet muscle on the expression and activity of the hypoxia-induced factor-1α (HIF-1α) in ...
N. S. Shcherbak   +2 more
doaj   +1 more source

Combined Preconditioning and Postconditioning Provides Synergistic Protection against Liver Ischemic Reperfusion Injury

open access: yesInternational Journal of Biological Sciences, 2012
Hepatic Ischemia and Reperfusion Injury (IRI) is a major cause of liver damage during liver surgery and transplantation. Ischemic preconditioning and postconditioning are strategies that can reduce IRI. In this study, different combined types of pre- and
Xiaoyu Song, Ning Zhang, Hongde XU, Liu Cao, Haipeng Zhang
doaj  

Myocardial Opioid Receptors in Conditioning and Cytoprotection

open access: yesPharmaceuticals, 2011
Opioid compounds and G-protein coupled opioid receptors (ORs) have been studied widely in terms of central nervous system (CNS) actions relating to pain management and drug abuse.
Grant Williams-Pritchard   +2 more
doaj   +1 more source

Ischemic postconditioning: mechanisms, comorbidities, and clinical application [PDF]

open access: yes, 2014
Since ischemic heart disease (IHD) is a major cause of mortality and heart failure, novel therapeutic strategies are expected to improve the clinical outcomes of patients with acute myocardial infarction.
Gelpi, Ricardo Jorge   +3 more
core   +1 more source

Postconditioning Hormesis Put in Perspective: An Overview of Experimental and Clinical Studies

open access: yesDose-Response, 2011
A beneficial effect of applying mild stress to cells or organisms, that were initially exposed to a high dose of stress, has been referred to as ‘postconditioning hormesis'.
F.A.C. Wiegant   +2 more
doaj   +1 more source

Ischemic postconditioning reduced myocardial ischemia-reperfusion injury: The roles of melatonin and uncoupling protein 3

open access: yesAnatolian Journal of Cardiology, 2019
Objective: Protective effects of ischemic postconditioning (PostC) decrease/disappear with age and chronic heart diseases. Similarly, low serum melatonin levels have been reported in the same risk groups.
Gülnur Aslan   +3 more
doaj   +1 more source

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