Results 41 to 50 of about 10,231,702 (322)
Random Walks for Spike-Timing Dependent Plasticity
, 2003 Random walk methods are used to calculate the moments of negative image equilibrium distributions in synaptic weight dynamics governed by spike-timing dependent plasticity (STDP).
Alan Williams +15 more
core +1 more source
Neuromorphic Learning towards Nano Second Precision [PDF]
, 2013 Temporal coding is one approach to representing information in spiking neural networks. An example of its application is the location of sounds by barn owls that requires especially precise temporal coding. Dependent upon the azimuthal angle, the arrival
Meier, Karlheinz +3 more
core +1 more source
Synaptic actions of amyotrophic-lateral-sclerosis-associated G85R-SOD1 in the squid giant synapse [PDF]
, 2020 © The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Song, Y.
Song, Yuyu
core +1 more source
Rethinking the Role of Normalization and Residual Blocks for Spiking Neural Networks
Sensors, 2022 Biologically inspired spiking neural networks (SNNs) are widely used to realize ultralow-power energy consumption. However, deep SNNs are not easy to train due to the excessive firing of spiking neurons in the hidden layers.
Shin-ichi Ikegawa +3 more
doaj +1 more source
Activity-dependent refinement of axonal projections forms one-to-one connection pattern in the developing chick ciliary ganglion. [PDF]
Front Cell NeurosciAlthough it is well established that initially overproduced synaptic connections are extensively remodeled through activity-dependent competition for postsynaptic innervation, the mechanisms determining the final number of postsynaptic targets per axon ...
Egawa R, Yawo H, Kuba H.
europepmc +2 more sources
Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse [PDF]
, 2017 Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. We found that these channels can be activated in neurons of the medial nucleus of the trapezoid body (MNTB) of the auditory system in ...
Di Guilmi, Mariano Nicolás +3 more
core +1 more source
Preparation of Pre- and Post-synaptic Density Fraction from Mouse Cortex
Bio-Protocol, 2013 The understanding of the organization of postsynaptic signaling systems at excitatory synapses has been aided by the identification of proteins in the postsynaptic density (PSD) fraction, a subcellular fraction enriched in structures with the morphology ...
Chengyong Shen, Yong-Jun Chen
doaj +1 more source
Frontiers in Cellular Neuroscience, 2020 Non-evoked miniature release of neurotransmitters is increasingly recognized as playing an important role in neural function and is implicated in synaptic plasticity, metaplasticity, and homeostasis.
Henry B. C. Taylor +4 more
doaj +1 more source
Molecular Brain, 2021 The SH3 and multiple ankyrin repeat domains 3 (Shank3) protein is a core organizer of the macromolecular complex in excitatory postsynapses, and its defects cause numerous synaptopathies, including autism spectrum disorders.
Chunmei Jin +13 more
doaj +1 more source
Targeting the post-synaptic proteome has therapeutic potential for psychosis in Alzheimer Disease
Communications Biology, 2023 Individuals with Alzheimer Disease who develop psychotic symptoms (AD + P) experience more rapid cognitive decline and have reduced indices of synaptic integrity relative to those without psychosis (AD-P).
J. M. Krivinko +9 more
doaj +1 more source