Results 41 to 50 of about 10,942,539 (365)
Neuromodulation of Chemical Synaptic Transmission Driven by THz Photons
Research, 2022 Postsynaptic currents of chemical synapse are modulated by multitudinous neurotransmitters, such as acetylcholine, dopamine, glutamate, and γ-aminobutyric acid, many of which have been used in the treatment of neurological diseases.
Xiaoxuan Tan +3 more
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Human synapses show a wide temporal window for spike-timing-dependent plasticity
Frontiers in Synaptic Neuroscience, 2010 Throughout our lifetime, activity-dependent changes in neuronal connection strength enable the brain to refine neural circuits and learn based on experience.
Guilherme T Silva +7 more
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Rethinking the Role of Normalization and Residual Blocks for Spiking Neural Networks
Sensors, 2022 Biologically inspired spiking neural networks (SNNs) are widely used to realize ultralow-power energy consumption. However, deep SNNs are not easy to train due to the excessive firing of spiking neurons in the hidden layers.
Shin-ichi Ikegawa +3 more
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Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4. [PDF]
, 2014 Lrp4, the muscle receptor for neuronal Agrin, is expressed in the hippocampus and areas involved in cognition. The function of Lrp4 in the brain, however, is unknown, as Lrp4-/- mice fail to form neuromuscular synapses and die at birth.
Burden, Steven J +2 more
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Preparation of Pre- and Post-synaptic Density Fraction from Mouse Cortex
Bio-Protocol, 2013 The understanding of the organization of postsynaptic signaling systems at excitatory synapses has been aided by the identification of proteins in the postsynaptic density (PSD) fraction, a subcellular fraction enriched in structures with the morphology ...
Chengyong Shen, Yong-Jun Chen
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Cell Reports, 2022 Summary: Neurexins (NRXNs) are key presynaptic cell adhesion molecules that regulate synapse formation and function via trans-synaptic interaction with postsynaptic ligands.
Takeshi Uemura +13 more
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eLife, 2020 In the cerebellar cortex, molecular layer interneurons use chemical and electrical synapses to form subnetworks that fine-tune the spiking output of the cerebellum.
Andreas Hoehne +2 more
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Targeting the post-synaptic proteome has therapeutic potential for psychosis in Alzheimer Disease
Communications Biology, 2023 Individuals with Alzheimer Disease who develop psychotic symptoms (AD + P) experience more rapid cognitive decline and have reduced indices of synaptic integrity relative to those without psychosis (AD-P).
J. M. Krivinko +9 more
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Effects of guanidine on synaptic transmission in the spinal cord of the frog [PDF]
, 1977 The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
A. K�hner +19 more
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Computational and Structural Biotechnology JournalThe relationship between oxidative stress and glycine receptors is complex, involving multiple mechanisms through which reactive oxygen species can modify glycine receptor function. Understanding these interactions is essential for developing therapeutic
Sanung Eom +9 more
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