Results 121 to 130 of about 52,072 (220)
Journal of Inflammation ResearchWenjuan Yi,1 Qionglin Bao,2 Dingkun Xu,3 Chenyu Long,1 Ruixin Fang,1 Wenlin Cheng,4 Jiquan Song,1 Huiting Feng1 1Department of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan, People’s Republic of China; 2Wound Repair Center, Chronic Wound and ...
Yi W +7 more
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Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers
eLife, 2014 During M phase, Endosulfine (Endos) family proteins are phosphorylated by Greatwall kinase (Gwl), and the resultant pEndos inhibits the phosphatase PP2A-B55, which would otherwise prematurely reverse many CDK-driven phosphorylations.
Byron C Williams +6 more
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Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by α4 Protein in HEK293 Cells
International Journal of Biological Sciences, 2011 Protein phosphatase 2A (PP2A) is a major protein phosphatase with important cell functions. Known and utilized as a potent inhibitor of PP2A, microcystin-LR (MCLR) targets PP2A as a core element that affects numerous cellular mechanisms.
Tan Li, Pu Huang, Jing Liang, Wenyu Fu, Zonglou Guo, Lihong Xu
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Altering phosphorylation in cancer through PP2A modifiers
Cancer Cell InternationalProtein phosphatase 2A (PP2A) is a serine/threonine phosphatase integral to the regulation of many cellular processes. Due to the deregulation of PP2A in cancer, many of these processes are turned toward promoting tumor progression. Considerable research
Hannah Johnson +2 more
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Regular ternary triangular forms
, 2019 An integer of the form $T_x=\frac{x(x+1)}2$ for some positive integer $x$ is called a triangular number. A ternary triangular form $aT_{x}+bT_{y}+cT_{z}$ for positive integers $a,b$ and $c$ is called regular if it represents every positive integer that ...
Kim, Mingyu, Oh, Byeong-Kweon
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Protein foszfatáz 2A szerepe a human endothelium barrier funkciójának szabályozásában = Role of protein phosphatase 2A in the regulation of human endothelial barrier function [PDF]
, 2008 Tüdő artéria endothel modell rendszerben tanulmányoztuk a protein foszfatáz 2A (PP2A) szerepét. Eredményeink arra utalnak, hogy a PP2A aktívan részt vesz az endothelium barrier funkciójának citoszkeletális fehérjéken keresztül történő regulációjában ...
Csortos, Csilla +2 more
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GABA(A) receptor phospho-dependent modulation is regulated by phospholipase C-related inactive protein type 1, a novel protein phosphatase 1 anchoring protein [PDF]
, 2004 GABA(A) receptors are critical in controlling neuronal activity. Here, we examined the role for phospholipase C-related inactive protein type 1 (PRIP-1), which binds and inactivates protein phosphatase 1alpha (PP1alpha) in facilitating GABA(A) receptor ...
Akaike, N +10 more
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Journal of Biological ChemistryDysregulation of phosphorylation-dependent signaling is a hallmark of tumorigenesis. Protein phosphatase 2 (PP2A) is an essential regulator of cell growth. One scaffold subunit (A) binds to a catalytic subunit (C) to form a core AC heterodimer, which together with one of many regulatory (B) subunits forms the active trimeric enzyme.
Franziska Wachter +4 more
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Scientific ReportsAlveolar capillary barrier disruption induces local edema and inflammation that impairs pulmonary function and promotes alveolar destruction in COPD. This study aimed to determine how cigarette smoke modulated the serine-threonine phosphatase protein ...
Abdoulaye J. Dabo +7 more
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