Results 11 to 20 of about 886,795 (250)

The epidemiology of premature aging and associated comorbidities [PDF]

Clinical Interventions in Aging, 2013
Fabio Coppedè Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy Abstract: Hutchinson–Gilford Progeria Syndrome and Werner syndrome, also known as childhood- and adulthood ...
Coppedè F
doaj   +2 more sources

Testicular aging, male fertility and beyond

Frontiers in Endocrinology, 2022
Normal spermatogenesis and sperm function are crucial for male fertility. The effects of healthy testicular aging and testicular premature aging on spermatogenesis, sperm function, and the spermatogenesis microenvironment cannot be ignored. Compared with
Shijue Dong, Chen Chen, Jiali Zhang, Yuan Gao, Xuhui Zeng, Xiaoning Zhang   +5 more
doaj   +1 more source

Impact of age, antiretroviral therapy, and cancer on epigenetic aging in people living with HIV

Cancer Medicine, 2023
Background Premature aging has been identified as a global risk factor for cancer. Causes of premature aging are multifactorial, including inflammation, infection, chronic stress, and lifestyle factors.
Yulan Qing, Ricky Chan, Pingfu Fu, Jennifer Cullen, Alexander Miron, Jeffrey M. Jacobson, John Pink, Stanton L. Gerson   +7 more
doaj   +1 more source

Increased Brain Age Gap Estimate (BrainAGE) in Young Adults After Premature Birth

Frontiers in Aging Neuroscience, 2021
Recent evidence suggests increased metabolic and physiologic aging rates in premature-born adults. While the lasting consequences of premature birth on human brain development are known, its impact on brain aging remains unclear.
Dennis M. Hedderich, Dennis M. Hedderich, Aurore Menegaux, Aurore Menegaux, Benita Schmitz-Koep, Benita Schmitz-Koep, Rachel Nuttall, Rachel Nuttall, Rachel Nuttall, Juliana Zimmermann, Juliana Zimmermann, Sebastian C. Schneider, Sebastian C. Schneider, Josef G. Bäuml, Marcel Daamen, Marcel Daamen, Henning Boecker, Marko Wilke, Claus Zimmer, Claus Zimmer, Dieter Wolke, Dieter Wolke, Peter Bartmann, Christian Sorg, Christian Sorg, Christian Sorg, Christian Gaser, Christian Gaser   +27 more
doaj   +1 more source

Benign prostatic hyperplasia in a 23 year old man with progeroid syndrome

African Journal of Urology, 2018
Introduction: Progeroid syndromes are characterized by accelerated aging and early development of diseases typically associated with aging. Premature development of tumors including BPH, maybe observed in these patients, which can lead to significant ...
M. Ahmed, A.T. Lawal, A. Bello, A. Abubakar, H.Y. Maitama   +4 more
doaj   +1 more source

Impact papers on aging in 2009 [PDF]

, 2010
The editorial board of Aging reviews research papers published in 2009,which they believe have or will have a significant impact on aging research.Among many others, the topics include genes that accelerate aging or incontrast promote longevity in model ...
Sassone-Corsi, Paolo, Skulachev, Vladimir P., Tilly, Jonathan L., Hall, Michael N., Nussenzweig, Andre, Brunet, Anne, Blagosklonny, Mikhail V., Karlseder, Jan, Osiewacz, Heinz D., Jr, Robert M. Brosh, Blasco, Maria A., Gudkov, Andrei V., Rando, Thomas A., Serrano, Manuel, Peeper, Daniel S., Gorospe, Myriam, Donehower, Lawrence A, Tilly, Jonathan Lee, Brosh, Robert M, Jr, Robert M Brosh, Helfand, Stephen L, Brosh, Robert M., Finch, Caleb E., Osiewacz, Heinz D, Tower, John, Helfand, Stephen L., Sinclair, David A, Rudolph, K Lenhard, Campisi, Judy, Bohr, Vilhelm A, Skulachev, Vladimir P, Bohr, Vilhelm A., Gudkov, Andrei V, DePinho, Ronald A., Verdin, Eric, Bartke, Andrzej, Depinho, Ronald A, Kroemer, Guido, Rudolph, K. Lenhard, Peeper, Daniel S, Vijg, Jan, Rando, Thomas A, Tilly, Jonathan L, Bonner, William M., Kenyon, Cynthia, Finkel, Toren, Sinclair, David A., Hekimi, Siegfried, Hall, Michael N, Bonner, William M, Longo, Valter, Sinclair, David, Sharpless, Norman E, Sharpless, Norman E., Blagosklonny, Mikhail V, Finch, Caleb E, Donehower, Lawrence A., Blasco, Maria A   +57 more
core   +2 more sources

Premature CD4+ T cell aging and its contribution to lymphopenia-induced proliferation of memory cells in autoimmune-prone non-obese diabetic mice.

PLoS ONE, 2014
Lymphopenia-induced proliferation (LIP), a mechanism to maintain a constant number of T cells in circulation, occurs in both normal aging and autoimmune disease.
Ting-Ting Sheu, Bor-Luen Chiang, Jui-Hung Yen, Wen-Chi Lin   +3 more
doaj   +1 more source

PREMATURE AGING MARKERS IN WOMEN OF REPRODUCTIVE AGE WITH HYPOPITUITARISM

Alʹmanah Kliničeskoj Mediciny, 2016
Background: Premature aging reduces quality of human life, leads to development of “old age diseases” in younger age, and also shortens life expectancy.
D. S. Mikhaylova, I. A. Ilovayskaya
doaj   +1 more source

Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome

Protein & Cell, 2018
Hutchinson-Gilford progeria syndrome (HGPS) and Werner syndrome (WS) are two of the best characterized human progeroid syndromes. HGPS is caused by a point mutation in lamin A (LMNA) gene, resulting in the production of a truncated protein product ...
Zeming Wu, Weiqi Zhang, Moshi Song, Wei Wang, Gang Wei, Wei Li, Jinghui Lei, Yu Huang, Yanmei Sang, Piu Chan, Chang Chen, Jing Qu, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte, Guang-Hui Liu   +14 more
doaj   +1 more source

Specific premature epigenetic aging of cartilage in osteoarthritis [PDF]

, 2016
Osteoarthritis (OA) is a disease affecting multiple tissues of the joints in the elderly, but most notably articular cartilage. Premature biological aging has been described in this tissue and in blood cells, suggesting a systemic component of premature ...
Rego Pérez, Ignacio, Real, Álvaro del, Gómez Reino, JJ, Zhang, Yuhua, Horvath, S, Mera Varela, A, Blanco García, Francisco J, Gómez-Reino, Juan J., López Golán, Y, Horvath, Steve, Zhang, Y, Zhai, G, López-Golán, Yolanda, González, A, González, Antonio, Riancho Moral, José Antonio, Blanco, FJ, Vidal-Bravo, Laura, Rego-Pérez, Ignacio, Riancho, José A., Zhai, Guangju, Mera-Varela, Antonio, Vidal Bralo, L, Real Bolt, Álvaro del   +23 more
core   +1 more source