Premature Aging in Young Cancer Survivors
Journal of the National Cancer Institute, 2019 Advances in early detection, treatment, and supportive care have resulted in an estimated 16 million cancer survivors who are alive in the United States today.
Šaro H Armenian +2 more
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PREMATURE AGING MARKERS IN WOMEN OF REPRODUCTIVE AGE WITH HYPOPITUITARISM
Alʹmanah Kliničeskoj Mediciny, 2016 Background: Premature aging reduces quality of human life, leads to development of “old age diseases” in younger age, and also shortens life expectancy.
D. S. Mikhaylova, I. A. Ilovayskaya
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Premature aging disorders: A clinical and genetic compendium
Clinical Genetics, 2020 Progeroid disorders make up a heterogeneous group of very rare hereditary diseases characterized by clinical signs that often mimic physiological aging in a premature manner.
Wollnik, Bernd +5 more
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The epidemiology of premature aging and associated comorbidities [PDF]
Clinical Interventions in Aging, 2013 Hutchinson-Gilford Progeria Syndrome and Werner syndrome, also known as childhood- and adulthood-progeria, respectively, represent two of the best characterized human progeroid diseases with clinical features mimicking physiological aging at an early age.
COPPEDE', FABIO, Coppedè F
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Repression of the Antioxidant NRF2 Pathway in Premature Aging
Cell, 2016 Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare, invariably fatal premature aging disorder. The disease is caused by constitutive production of progerin, a mutant form of the nuclear architectural protein lamin A, leading, through unknown ...
Nard Kubben, Weiqi Zhang, Jiping Yang
exaly +2 more sources
Sirtuin 1 and Skin: Implications in Intrinsic and Extrinsic Aging—A Systematic Review
Cells, 2021 Skin, as the outermost organ of the body, is constantly exposed to both intrinsic and extrinsic causative factors of aging. Intrinsic aging is related to compromised cellular proliferative capacity, and may be accelerated by harmful environmental ...
Katarzyna Kakareko +6 more
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Epigenetic Regulation of Skin Cells in Natural Aging and Premature Aging Diseases
Cells, 2018 Skin undergoes continuous renewal throughout an individual’s lifetime relying on stem cell functionality. However, a decline of the skin regenerative potential occurs with age.
Donata Orioli, Elena Dellambra
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IgG1 glycosylation highlights premature aging in Down syndrome. [PDF]
Aging CellDown syndrome (DS) is characterized by lowered immune competence and premature aging. We previously showed decreased antibody response following SARS-CoV-2 vaccination in adults with DS.
Streng BMM +13 more
europepmc +4 more sources
Dietary phytochemicals alleviate the premature skin aging: A comprehensive review
Experimental GerontologySkin aging, often called as premature skin aging, is the hastened deterioration of the skin resulting from multiple factors, including UV radiation, environmental contaminants, inadequate nutrition, stress, etc. Dietary phytochemicals, present in fruits,
Himanshu Gupta +11 more
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PML Nuclear Bodies and Cellular Senescence: A Comparative Study of Healthy and Premature Aging Syndrome Donors' Cells. [PDF]
CellsNatural aging and age-related diseases involve the acceleration of replicative aging, or senescence. Multiple proteins are known to participate in these processes, including the promyelocytic leukemia (PML) protein, which serves as a core component of ...
Smirnov EY +10 more
europepmc +2 more sources