Results 11 to 20 of about 3,663 (218)

Genome-Wide Analysis of the Cis-Prenyltransferase (CPT) Gene Family in Taraxacum kok-saghyz Provides Insights into Its Expression Patterns in Response to Hormonal Treatments [PDF]

Plants
Taraxacum kok-saghyz (TKS) is a natural rubber (NR)-producing plant with great development prospects. Accurately understanding the molecular mechanism of natural rubber biosynthesis is of great significance.
Liyu Zhang, Huan He, Jiayin Wang, Pingping Du, Lili Wang, Guangzhi Jiang, Lele Liu, Lu Yang, Xiang Jin, Hongbin Li, Quanliang Xie   +10 more
doaj   +2 more sources

Biosynthesis of novel cannabigerolic acid derivatives by engineering the substrate specificity of aromatic prenyltransferase [PDF]

Frontiers in Bioengineering and Biotechnology
IntroductionCannabinoids possess significant therapeutic potential, but their natural chemical diversity derived from plant biosynthesis is limited. Efficient biotransformation processes are required to expand the range of accessible cannabinoids.
Hoe-Suk Lee, Jisu Park, Jisu Park, Taejung Kim, Taejung Kim, Huitae Min, Seongsu Na, Seongsu Na, Soon Young Park, Young-Tae Park, Young-Tae Park, Young Joo Yeon, Jungyeob Ham, Jungyeob Ham, Jungyeob Ham   +14 more
doaj   +2 more sources

A novel prenyltransferase, farnesylgeranyl diphosphate synthase, from the haloalkaliphilic archaeon,Natronobacterium pharaonis

FEBS Letters, 1994
A novel prenyltransferase, farnesylgeranyl diphosphate (FGPP) synthase (EC 2.5.1.X), which synthesizes C25-prenyl diphosphate, was found in the haloalkaliphilic archaeon Natronobacterium pharaonis.
Akira Tachibana, Tachibana, Akira
exaly   +2 more sources

Structural mechanisms of allosteric regulation in the human cis-prenyltransferase complex [PDF]

Nature Communications
Human cis-prenyltransferase (hcis-PT) synthesizes long-chain isoprenoids essential for N-linked protein glycosylation. This heteromeric complex comprises the catalytic subunit DHDDS and the regulatory Nogo-B receptor (NgBR).
Moshe Giladi, Shiri Kredi, Carlo Guardiani, Lyr Aviram, Pavla Vaňková, Yarin Gaizinger, Petr Man, Alberto Giacomello, Yoni Haitin   +8 more
doaj   +2 more sources

Candida albicans cis-prenyltransferase Rer2 is required for protein glycosylation, cell wall integrity and hypha formation

Fungal Genetics and Biology, 2014
Cis-prenyltransferase is the first enzyme of the mevalonate pathway committed to the biosynthesis of dolichol in eukaryotes. The RER2 gene encoding cis-prenyltransferase (Rer2p) in the human fungal pathogen Candida albicans was characterized. In addition,
Katarzyna Gawarecka, Ewa Swiezewska, Joachim F Ernst   +2 more
exaly   +2 more sources

Prenylation of Flavanones by an Aromatic Prenyltransferase from Fusarium globosum [PDF]

Molecules
Prenylation increases the structural diversity and biological activity of flavonoids. In this study, an aromatic prenyltransferase, FgPT1, was identified from Fusarium globosum.
Dingtao Tang, Jiajie Quan, Zhengjiao Gao, Bingfeng He, Yu Hou, Peipei Fan, Meidong Pan, Jiali Yang   +7 more
doaj   +2 more sources

Structure and specificity of a permissive bacterial C-prenyltransferase [PDF]

Nature Chemical Biology, 2017
This study highlights the biochemical and structural characterization of the L-tryptophan C6 C-prenyltransferase (C-PT) PriB from Streptomyces sp. RM-5-8.
Subramanian, Thangaiah, Thorson, Jon S., Khaled A Shaaban, Shanteri Singh, H Peter Spielmann, George N Phillips, Spielmann, H.Peter, Shaaban, Khaled A., Mark L Farman, Singh, Shanteri, Ponomareva, Larissa V., Spielmann, H Peter, Larissa V Ponomareva, Sherif I Elshahawi, Hongnan Cao, Phillips, George N.Jr., Elshahawi, Sherif, Jon S Thorson, Phillips, George N., Jr., Spielmann, H. Peter, Thangaiah Subramanian, Cao, Hongnan, Elshahawi, Sherif I., Farman, Mark L, Farman, Mark L.   +24 more
core   +4 more sources

Reconstitution of prenyltransferase activity on nanodiscs by components of the rubber synthesis machinery of the Para rubber tree and guayule

Scientific Reports, 2022
Natural rubber of the Para rubber tree (Hevea brasiliensis) is synthesized as a result of prenyltransferase activity. The proteins HRT1, HRT2, and HRBP have been identified as candidate components of the rubber biosynthetic machinery.
Fu Kuroiwa, Akira Nishino, Yasuko Mandal, Masataka Honzawa, Miki Suenaga-Hiromori, Kakeru Suzuki, Yukie Takani, Yukino Miyagi-Inoue, Haruhiko Yamaguchi, Satoshi Yamashita, Seiji Takahashi, Yuzuru Tozawa   +11 more
doaj   +1 more source

Heterologous biosynthesis of isobavachalcone in tobacco based on in planta screening of prenyltransferases

Frontiers in Plant Science, 2022
Isobavachalcone (IBC) is a prenylated chalcone mainly distributed in some Fabaceae and Moraceae species. IBC exhibits a wide range of pharmacological properties, including anti-bacterial, anti-viral, anti-inflammatory, and anti-cancer activities. In this
Lirong Guo, Wei Zhao, Yan Wang, Yu Yang, Cuimei Wei, Jian Guo, Jianye Dai, Masami Yokota Hirai, Aike Bao, Zhigang Yang, Haijuan Chen, Yimeng Li, Yimeng Li, Yimeng Li   +13 more
doaj   +1 more source

Protein prenyltransferases [PDF]

Genome Biology, 2003
Three different protein prenyltransferases (farnesyltransferase and geranylgeranyltransferases I and II) catalyze the attachment of prenyl lipid anchors 15 or 20 carbons long to the carboxyl termini of a variety of eukaryotic proteins. Farnesyltransferase and geranylgeranyltransferase I both recognize a 'Ca1a2X' motif on their protein substrates ...
Maurer-Stroh, Sebastian, Washietl, Stefan, Eisenhaber, Frank   +2 more
openaire   +3 more sources