Results 31 to 40 of about 3,663 (218)

A heteromeric cis-prenyltransferase is responsible for the biosynthesis of glycosyl carrier lipids in Methanosarcina mazei [PDF]

, 2019
Cis-prenyltransferases are enzymes responsible for the biosynthesis of glycosyl carrier lipids, natural rubber, and some secondary metabolites. Certain organisms, including some archaeal species, possess multiple genes encoding cis-prenyltransferase ...
Sompiyachoke, Kitty, Emi, Koh-ichi, Hemmi, Hisashi, Okada, Miyako   +3 more
core   +1 more source

‐Prenyltransferase

, 2021
International audience: Cyanobactins comprise a widespread group of peptide metabolites produced by cyanobacteria that are often diversified by post-translational prenylation. Several enzymes have been identified in cyanobactin biosynthetic pathways that
Maho Morita, Morinaka, Brandon, I, Eric W. Schmidt, Schmidt, Eric, W, Sarkar, Snigdha, Mugilarasi Purushothaman, Muriel Gugger, Morita, Maho, Brandon I. Morinaka, Gugger, Muriel, Snigdha Sarkar, Purushothaman, Mugilarasi   +11 more
core   +1 more source

Type 1 polyisoprenoid diphosphate phosphatase modulates geranylgeranyl-mediated control of HMG CoA reductase and UBIAD1

eLife, 2021
UbiA prenyltransferase domain-containing protein-1 (UBIAD1) utilizes geranylgeranyl pyrophosphate (GGpp) to synthesize the vitamin K2 subtype menaquinone-4. The prenyltransferase has emerged as a key regulator of sterol-accelerated, endoplasmic reticulum
Rania Elsabrouty, Youngah Jo, Seonghwan Hwang, Dong-Jae Jun, Russell A DeBose-Boyd   +4 more
doaj   +1 more source

Transient Prenyltransferase–Cyclase Association in Fusicoccadiene Synthase, an Assembly-Line Terpene Synthase

, 2022
Fusicoccadiene synthase from the fungus Phomopsis amygdali (PaFS) is an assembly-line terpene synthase that catalyzes the first two steps in the biosynthesis of Fusiccocin A, a diterpene glycoside.
Jacque L. Faylo (13954626), Kushol Gupta (1435129), Kenji Murakami (1903816), Trevor van Eeuwen (13954629), David W. Christianson (1294293)   +4 more
core   +1 more source

Human geranylgeranyl diphosphate synthase: isolation of the cDNA, chromosomal mapping and tissue expression

Journal of Lipid Research, 1998
We report the nucleotide sequence of human geranylgeranyl diphosphate (GGPP) synthase cDNA isolated from a fetal heart library. The 2.5 kb cDNA encodes a protein of 34 kDa.
Johan Ericsson, John M. Greene, Kenneth C. Carter, Brenda K. Shell, D. Roxanne Duan, Charles Florence, Peter A. Edwards   +6 more
doaj   +1 more source

Crystal Structure of Geranylgeranyl Pyrophosphate Synthase (CrtE) Involved in Cyanobacterial Terpenoid Biosynthesis

Frontiers in Plant Science, 2020
Cyanobacteria are photosynthetic prokaryotes that perform oxygenic photosynthesis. Due to their ability to use the photon energy of sunlight to fix carbon dioxide into biomass, cyanobacteria are promising hosts for the sustainable production of ...
Yuchi Feng, R. Marc L. Morgan, Paul D. Fraser, Klaus Hellgardt, Peter J. Nixon   +4 more
doaj   +1 more source

Enhancing flavonoid production by promiscuous activity of prenyltransferase, BrPT2 from Boesenbergia rotunda [PDF]

PeerJ, 2020
Flavonoids and prenylated flavonoids are active components in medicinal plant extracts which exhibit beneficial effects on human health. Prenylated flavonoids consist of a flavonoid core with a prenyl group attached to it.
Yvonne Jing Mei Liew, Yean Kee Lee, Norzulaani Khalid, Noorsaadah Abd Rahman, Boon Chin Tan   +4 more
doaj   +2 more sources

Enzymatic studies on aromatic prenyltransferases [PDF]

Journal of Natural Medicines, 2020
AbstractAromatic prenyltransferases (PTases), including ABBA-type and dimethylallyl tryptophan synthase (DMATS)-type enzymes from bacteria and fungi, play important role for diversification of the natural products and improvement of the biological activities.
openaire   +2 more sources

Characterization of an Isoflavonoid-Specific Prenyltransferase from Lupinus albus [PDF]

, 2012
Article on the characterization of an isoflavonoid-specific prenyltransferase from Lupinus ...
Huhman, David, Shen, Guoan, Snyder, John, Sumner, Lloyd W., Dixon, R. A., Lei, Zhentian   +5 more
core   +1 more source

Molecular basis for the plasticity of aromatic prenyltransferases in hapalindole biosynthesis

Beilstein Journal of Organic Chemistry, 2019
Aromatic prenyltransferases (PTases) are enzymes that catalyze Friedel–Crafts reactions between aromatic compounds and isoprenoid diphosphates. In hapalindole biosynthesis, the aromatic PTases AmbP1 and AmbP3 exhibit surprisingly plastic selectivities ...
Takayoshi Awakawa, Ikuro Abe
doaj   +1 more source