Results 51 to 60 of about 3,960 (214)

Evolutionary Developments in Plant Specialized Metabolism, Exemplified by Two Transferase Families

open access: yesFrontiers in Plant Science, 2019
Plant specialized metabolism emerged from the land colonization by ancient plants, becoming diversified along with plant evolution. To date, more than 1 million metabolites have been predicted to exist in the plant kingdom, and their metabolic processes ...
Hiroaki Kusano   +5 more
doaj   +1 more source

Structure of a membrane-embedded prenyltransferase homologous to UBIAD1. [PDF]

open access: yesPLoS Biology, 2014
Membrane-embedded prenyltransferases from the UbiA family catalyze the Mg2+-dependent transfer of a hydrophobic polyprenyl chain onto a variety of acceptor molecules and are involved in the synthesis of molecules that mediate electron transport ...
Hua Huang   +5 more
doaj   +1 more source

Microbial soluble aromatic prenyltransferases for engineered biosynthesis

open access: yesSynthetic and Systems Biotechnology, 2021
Prenyltransferase (PTase) enzymes play crucial roles in natural product biosynthesis by transferring isoprene unit(s) to target substrates, thereby generating prenylated compounds.
He-Ping Chen, Ikuro Abe
doaj   +1 more source

Metabolic Labeling and Visualization of Isoprenoids Using Alkyne‐Modified DMAPP Analogs in Bacillus subtilis

open access: yesAngewandte Chemie, Volume 138, Issue 35, 24 August 2026.
Fluorescence‐based visualization and targeted mass–spectrometric enrichment of membrane‐embedded isoprenoids in Bacillus subtilis via cell‐permeant, alkynylated DMAPP analogs. ABSTRACT Isoprenoids are a chemically and functionally diverse class of metabolites that underlie essential bacterial physiology including respiration and cell envelope ...
Zackary N. Hulsey   +7 more
wiley   +2 more sources

Structure, catalysis, and inhibition mechanism of prenyltransferase [PDF]

open access: yesIUBMB Life, 2020
AbstractIsoprenoids, also known as terpenes or terpenoids, represent a large family of natural products composed of five‐carbon isopentenyl diphosphate or its isomer dimethylallyl diphosphate as the building blocks. Isoprenoids are structurally and functionally diverse and include dolichols, steroid hormones, carotenoids, retinoids, aromatic ...
Hsin‐Yang Chang   +2 more
openaire   +2 more sources

Human UBIAD1 Prenyltransferase Activity.

open access: yes, 2015
(A) Effect of DTT on prenyltransferase activity of human UbiA prenyltransferase domain-containing protein 1 (UBIAD1). (B) pH dependence of prenyltransferase activity of human UBIAD1.
Naoko Okuda (724165)   +10 more
core   +1 more source

Identification and reconstitution of the rubber biosynthetic machinery on rubber particles from Hevea brasiliensis

open access: yeseLife, 2016
Natural rubber (NR) is stored in latex as rubber particles (RPs), rubber molecules surrounded by a lipid monolayer. Rubber transferase (RTase), the enzyme responsible for NR biosynthesis, is believed to be a member of the cis-prenyltransferase (cPT ...
Satoshi Yamashita   +12 more
doaj   +1 more source

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase

open access: yeseLife, 2015
Schnyder corneal dystrophy (SCD) is an autosomal dominant disorder in humans characterized by abnormal accumulation of cholesterol in the cornea.
Marc M Schumacher   +4 more
doaj   +1 more source

Identification of the new prenyltransferase Ubi-297 from marine bacteria and elucidation of its substrate specificity

open access: yesBeilstein Journal of Organic Chemistry, 2022
Aromatic prenylated metabolites have important biological roles and activities in all living organisms. Compared to their importance in all domains of life, we know relatively little about their substrate scopes and metabolic functions. Here, we describe
Jamshid Amiri Moghaddam   +4 more
doaj   +1 more source

A novel prenyltransferase, farnesylgeranyl diphosphate synthase, from the haloalkaliphilic archaeon, Natronobacterium pharaonis [PDF]

open access: yes, 1994
A novel prenyltransferase, farnesylgeranyl diphosphate (FGPP) synthase (EC 2.5.1.X), which synthesizes C25-prenyl diphosphate, was found in the haloalkaliphilic archaeon Natronobacterium pharaonis.
Akira Tachibana, Tachibana, Akira
core   +1 more source

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