Uncoupled Packaging of Amyloid Precursor Protein and Presenilin 1 into Coat Protein Complex II Vesicles [PDF]
, 2004 Jin Oh Kim +4 more
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Navigating the treatment landscape of Alzheimer's disease: Current strategies and future directions
IbrainAlzheimer's disease (AD), a neurodegenerative disease leading to dementia, lacks a single definitive diagnosis. While current medications only manage symptoms, the ideal treatment would restore cognition.
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PRESENILIN 1 mutations causing early-onset familial Alzheimer’s disease or familial acne inversa differ in their effects on genes facilitating energy metabolism and signal transduction [PDF]
, 2021 Karissa Barthelson +3 more
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Familial Frontotemporal Dementia-Associated Presenilin-1 c.548G>T Mutation Causes Decreased mRNA Expression and Reduced Presenilin Function in Knock-In Mice [PDF]
, 2012 Hirotaka Watanabe +4 more
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C-Terminal Maturation Fragments of Presenilin 1 and 2 Control Secretion of APPα and Aβ by Human Cells and Are Degraded by Proteasome [PDF]
, 1999 Cristine Alvès da Costa +2 more
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Identify the Binding Interface between Calsenilin and Presenilin 1 C-Terminal Fragment [PDF]
, 2015 Khoa Pham, Jaroslava Mikšovská
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Mutations, associated with early-onset Alzheimer’s disease, discovered in Asian countries
Clinical Interventions in Aging, 2016 Eva Bagyinszky,1,* Young Chul Youn,2 Seong Soo A An,1 SangYun Kim3,* 1Department of BioNano Technology, Gachon University, Gyeonggi-do, 2Department of Neurology, College of Medicine, Chung-Ang University, Seoul, 3Department of Neurology, Seoul National ...
Bagyinszky E, Youn YC, An SSA, Kim S
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Presenilin 1 transgene addition to amyloid precursor protein overexpressing transgenic rats increases amyloid beta 42 levels and results in loss of memory retention [PDF]
, 2016 Cansu Agca +5 more
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Molecular characterization and temporal expression profiling of presenilins in the developing porcine brain [PDF]
, 2007 Lone Bruhn Madsen +7 more
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