Results 171 to 180 of about 16,662 (259)

Yeast Prions: Discovery, Nature, Cellular Manipulation and Implication. [PDF]

J Microbiol Biotechnol
Son M.
europepmc   +1 more source

Intracellular trafficking SNARE protein, syntaxin-6, modifies prion cellular phenotypes and risk of disease development in vivo. [PDF]

Acta Neuropathol
Hill E, Patel M, Ribes JM, Linehan J, Zhang F, Jakubcova T, Hamdan S, Tomlinson A, Ercolani T, Schmidt C, Ahmed P, Thirlway G, Argentina F, Marinho AT, Jones E, Kaye N, Fitzhugh C, Jackson GS, Brandner S, Kloehn P, Collinge J, Cunningham TJ, Mead S.   +22 more
europepmc   +1 more source

Beyond prion-like spreading in neurodegenerative disease. [PDF]

Alzheimers Dement
Meisl G, Rowe JB, Klenerman D.
europepmc   +1 more source

Characterization of the prion protein in relation to normal cellular function and in disease

, 2012
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a group of rare and fatal neurodegenerative disorders that can affect both human and animals. Evidence indicates that the key event in prion disease pathogenesis is the conformational conversion of the normal cellular prion protein (PrPC) into an aggregated isoform ...
openaire   +1 more source

Infecting human brain organoids with FFI or sCJD preserves prion traits regardless of host genotype. [PDF]

NPJ Dement
Groveman BR, Foliaki ST, Williams K, Orrù CD, Race B, Zanusso G, Haigh CL.   +6 more
europepmc   +1 more source

Parkinson\u27s disease and multiple system atrophy have distinct α-synuclein seed characteristics [PDF]

, 2019
Cairns, Nigel J., Dhavale, Dhruva D., Diamond, Marc I., Furman, Jennifer L., Holmes, Brandon B., Kotzbauer, Paul T., Song, Eun-Suk, Su, Bryant W., Yamasaki, Tritia R.   +8 more
core   +1 more source

The Strain Properties of Korean and North American Chronic Wasting Disease Prions Are Indistinguishable. [PDF]

J Infect Dis
Sohn HJ, DeFranco JP, Park HC, Park KJ, Bian J, Crowell J, Kim S, Webster BK, Kang HE, Telling GC.   +9 more
europepmc   +1 more source

NMR structure of the human prion protein with the pathological Q212P mutation reveals unique structural features. [PDF]

, 2010
Giachin, G, Jaremko, Mariusz, Jaremko, Łukasz, Legname, G   +3 more
core   +1 more source

Prions and protein aggregates as pathogens, self-propagating structures, biomarkers, and therapeutic targets. [PDF]

Microbiol Mol Biol Rev
Caughey B, Artikis E, Shoup D, Orrú CD, Alam P, Parveen S, King S, Soukup J, Hughson AG, Priola SA.   +9 more
europepmc   +1 more source

Prion 2024 conference: from two decades of growth to a new journey forward. [PDF]

Prion
Kong Y, Huang P, Shi Q, Wang Y, Li M, Ma J, Dong XP, Hong D, Zou WQ.   +8 more
europepmc   +1 more source