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Special Issue: Molecular Research on Mental Disorders 2.0. [PDF]
Int J Mol SciSowa-Kućma M.
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Homogenization Reveals Large-Scale Dynamics in the Spread of Chronic Wasting Disease. [PDF]
Bull Math BiolMcClure J, Powell J.
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Metallothioneins in Prion- and Amyloid-Related Diseases
Journal of Alzheimer's Disease, 2016Prion and other amyloid-forming diseases represent a group of neurodegenerative disorders that affect both animals and humans. The role of metal ions, especially copper and zinc is studied intensively in connection with these diseases. Their involvement in protein misfolding and aggregation and their role in creation of reactive oxygen species have ...
Pavlína, Adam +8 more
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Molecular and chemical basis of prion-related diseases
Chemical Society Reviews, 1997Prion-related diseases include scrapie in sheep, bovine spongiform encephalopathy in cattle and Creutzfeldt-Jakob disease in humans. The infectious agent for these diseases surprisingly contains no nucleic acid, but is a protein(PrP) which exists in two conformations, PrPC and PrPSc.
Sheila B. L. Ng, Andrew J. Doig
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Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases [PDF]
Biochemical Journal, 2013 Genetic Creutzfeldt–Jakob disease, Gerstmann–Sträussler–Scheinker syndrome, fatal familial insomnia and prion protein cerebral amyloid angiopathy are clinically and neuropathologically distinct neurodegenerative diseases linked to mutations in the PRNP gene encoding the cellular prion protein (PrPC). How sequence variants of PRNP encode the information
Tapella, Laura +5 more
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Amyloid in alzheimer's disease and prion-related encephalopathies: Studies with synthetic peptides
Progress in Neurobiology, 1996Deposition of amyloid-beta protein (beta A) in brain parenchyma and vessel walls is a major pathological feature of Alzheimer's disease (AD). In prion-related encephalopathies (PRE), too, an altered form of prion protein (PrPsc) forms amyloid fibrils and accumulates in the brain.
G, Forloni +3 more
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Rejuvenation Research, 2008
Prion diseases, Alzheimer's disease, and Parkinson's disease are age-related neurodegenerative diseases that are characterized by the formation of protein aggregates during the progress of the disease. Although it is still not known whether these aggregates are causative for, or symptoms of, the disease.
Eva, Birkmann +5 more
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Prion diseases, Alzheimer's disease, and Parkinson's disease are age-related neurodegenerative diseases that are characterized by the formation of protein aggregates during the progress of the disease. Although it is still not known whether these aggregates are causative for, or symptoms of, the disease.
Eva, Birkmann +5 more
openaire +2 more sources