Results 21 to 30 of about 2,679,159 (249)
Calcitonin gene-related peptide is a stimulator of renin secretion [PDF]
, 1988 Calcitonin gene-related peptide (CGRP) was found to stimulate renin secretion in vivo in normal human volunteers. Moreover, CGRP stimulated the release of renin in vitro from isolated rat renal juxtaglomerular cells (half-maximal effective concentration [
Fischer, J. A. +19 more
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Disparate effects of calcium channel blockers on pressure dependence of renin secretion and flow in the isolated perfused rat kidney [PDF]
, 1992 Using the model of isolated perfused rat kidneys this study was performed to investigate whether or not voltage-operated calcium channels are essentially involved in the pressure control of renin secretion from the kidneys. At a perfusion pressure of 100
Scholz, Holger, Kurtz, Armin
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International Journal of Nephrology, 2019 Objective. The nephron (pro)renin receptor may play a pathophysiological role in renal disorders in hypertension or diabetes. The aim of this study was to determine the relationship of (pro)renin receptors and transdifferentiation between the renin ...
Zsolt Razga +4 more
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Calmodulin antagonists stimulate renin secretion and inhibit renin synthesis in vitro [PDF]
, 1992 To find out whether calmodulin activity could be a common denominator for the cellular control of renin secretion and synthesis, we have examined the effects of calmodulin antagonists on the secretion and the synthesis of renin in primary cultures of ...
Kurtz, Armin +7 more
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PLoS ONE, 2018 Antithyroid drugs are generally selected as the first-line treatment for Graves' Disease (GD); however, the existence of patients showing resistance or severe side effects to these drugs is an important issue to be solved. The (pro)renin receptor [(P)RR]
Yuki Mizuguchi +11 more
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Expression of renin–angiotensin system (RAS) components in endometrial cancer
Endocrine Connections, 2017 A dysfunctional endometrial renin–angiotensin system (RAS) could aid the growth and spread of endometrial cancer. To determine if the RAS is altered in endometrial cancer, we measured RAS gene expression and protein levels in 30 human formalin-fixed ...
Sarah J Delforce +9 more
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Endocrine Regulations, 2016 Adipose tissue expresses all the renin-angiotensin system (RAS) components that play an important role in the adipogenesis, lipid and glucose metabolism regulation in an auto/paracrine manner.
Slamkova M, Zorad S, Krskova K
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Role of Nonclassical Renin-angiotensin system Axis In Renal Fibrosis
Frontiers in Physiology, 2015 The renin–angiotensin system (RAS) is a major regulator of renal fibrosis. Besides the classical renin/Angiotensin-converting enzyme 2 (ACE2)/angiotensin II (Ang II)/AT1 and AT2 axis, multiple new axes have been recently described.
Linli eLv, Bi-Cheng eLiu
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The role of (pro)renin receptor and its soluble form in cardiovascular diseases
Frontiers in Cardiovascular Medicine, 2023 The renin-angiotensin system (RAS) is a major classic therapeutic target for cardiovascular diseases. In addition to the circulating RAS, local tissue RAS has been identified in various tissues and plays roles in tissue inflammation and tissue fibrosis. (
Boyang Wang +9 more
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Is (Pro)Renin Receptor a Multifunctional Receptor? [PDF]
Hypertension, 2010 The existence of various components of the renin-angiotensin system in the eye has been known for more than a decade, and the importance of this system in ocular pathophysiology is a subject of active investigation.1 It has long been recognized that prorenin, an inactive precursor of renin, is elevated in the ocular fluids of patients with diabetic ...
Qiuhong Li, Mohan K. Raizada
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